碘克沙醇

Description

Iodixanol · CAS 92339-11-2 · C35H44I6N6O15. UNII HW8W27HTXX. Melting Point: 240-250 °C; Solubility: 1.85e-01 g/L; Density: 1.266.

Identification

CAS Registry Number	92339-11-2
PubChem CID	3724
Molecular formula	C35H44I6N6O15
IUPAC name	5-[acetyl-[3-[N-acetyl-3,5-bis(2,3-dihydroxypropylcarbamoyl)-2,4,6-triiodoanilino]-2-hydroxypropyl]amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
UNII (FDA)	HW8W27HTXX

Computed Descriptors

Molecular Weight	1550.2
XLogP3	-3.4
Hydrogen Bond Donor Count	13
Hydrogen Bond Acceptor Count	15
Rotatable Bond Count	22
Exact Mass	1549.7133
Monoisotopic Mass	1549.7133
Topological Polar Surface Area	339
Heavy Atom Count	62
Formal Charge	0

Physical & Chemical Properties

Melting Point	240-250 °C
Solubility	1.85e-01 g/L
Density	1.266
LogP	0.5
Viscosity	11.1 mPa at 37 °C
pH	7.2-7.6 (c = 320 mg I/L)

Physical description & handling notes

• Solid
• Soluble in water
• Osmolality 290 mOsm/kg H2O
• Iodixanol is a contrast agent commonly used during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents. It is an imaging contrast agent with the same osmolality as blood (290mOsm/kg H20).
• Visipaque

Documented Uses

• Use (kg; approx.) in Germany (2009): >5000
• Use (kg; exact) in Germany (2009): 6842
• Consumption (g per capita; approx.) in Germany (2009): 0.0611
• Consumption (g per capita; exact) in Germany (2009): 0.0836
• Consumption (g per capita) in the USA (2002): 0.126
• Preparation: P.E. Hansen et al., EP 108638 (1984 to Nyegaard)

Synonyms

iodixanol; 92339-11-2; Visipaque; Indixanol; Iodixanolum; Visipaque 270; Visipaque 320; OptiPrep; DTXSID2045523; 2-5410-3A; NSC-760069; HW8W27HTXX; 5,5'-((2-Hydroxytrimethylene)bis(acetylimino))bis(N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide); 2-541O-3A; DTXCID0025523; CHEBI:31705

Frequently Asked Questions

What are the CAS number and molecular formula of Iodixanol?

CAS 92339-11-2; molecular formula C35H44I6N6O15; molecular weight — g/mol.

What other names is Iodixanol known by?

iodixanol, 92339-11-2, Visipaque, Indixanol, Iodixanolum, Visipaque 270.

What are the key physical properties of Iodixanol?

Melting Point: 240-250 °C; Solubility: 1.85e-01 g/L; Density: 1.266; LogP: 0.5.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.