Gepotidacin

Description

Gepotidacin · CAS 1075236-89-3 · C24H28N6O3. UNII DVF0PR037D.

Identification

CAS Registry Number	1075236-89-3
PubChem CID	25101874
Molecular formula	C24H28N6O3
IUPAC name	(3R)-3-[[4-(3,4-dihydro-2H-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.04,12]dodeca-6,8(12),9-triene-5,11-dione
UNII (FDA)	DVF0PR037D

Computed Descriptors

Molecular Weight	448.5
XLogP3	0.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	5
Exact Mass	448.22228878
Monoisotopic Mass	448.22228878
Topological Polar Surface Area	90.4
Heavy Atom Count	33
Formal Charge	0

GHS Hazard Classification

Reported hazard statements	H373 (100%)

Documented Uses

• Gepotidacin is a unique and recently approved antibiotic used for oral treatment of uncomplicated urinary tract infections and urogenital gonorrhea. Gepotidacin therapy is given in short courses of 1 or 5 days and has not been associated with elevations in serum aminotransferase levels or clinically apparent liver injury.
• Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents, Urinary; Antibacterial Agents
• Antibiotics, Triazaacenaphthylene
• Take with food. Gepotidacin should be administered after a meal to mitigate gastrointestinal intolerance.
• Compounds that inhibit the activity of DNA TOPOISOMERASES.
• Established Pharmacologic Class [EPC] - Triazaacenaphthylene Bacterial Type II Topoisomerase Inhibitor

Synonyms

Gepotidacin; 1075236-89-3; GSK-2140944; Gepotidacina; Gepotidacine; DVF0PR037D; DTXSID501028208; gepotidacinum; RefChem:639850; DTXCID501513790; GSK2140944; GSK 2140944; Blujepa; Gepotidacin [USAN:INN]; UNII-DVF0PR037D; Gepotidacin [INN]

Frequently Asked Questions

What are the CAS number and molecular formula of Gepotidacin?

CAS 1075236-89-3; molecular formula C24H28N6O3; molecular weight — g/mol.

What other names is Gepotidacin known by?

Gepotidacin, 1075236-89-3, GSK-2140944, Gepotidacina, Gepotidacine, DVF0PR037D.

Is Gepotidacin classified as hazardous?

Hazard statements reported: H373.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.