钆喷酸二葡胺

Description

Gadopentetate dimeglumine · CAS 86050-77-3 · C28H54GdN5O20. UNII RH248G8V27.

Identification

CAS Registry Number	86050-77-3
PubChem CID	55466
Molecular formula	C28H54GdN5O20
IUPAC name	2-[bis[2-[carboxylatomethyl(carboxymethyl)amino]ethyl]amino]acetate;gadolinium(3+);bis((2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol)
UNII (FDA)	RH248G8V27

Computed Descriptors

Molecular Weight	938.0
Hydrogen Bond Donor Count	14
Hydrogen Bond Acceptor Count	25
Rotatable Bond Count	25
Exact Mass	938.26033
Monoisotopic Mass	938.26033
Topological Polar Surface Area	431
Heavy Atom Count	54
Formal Charge	0
Complexity	631

Physical description & handling notes

• Freely soluble in water
• Osmolality at 37 °C = 1,960; Viscosity (cP) = 4.9 at 20 °C, 2.9 at 37 °C; Density = 1.195 at 25 °C; Specific gravity = 1.208 at 25 °C; LogPw = -5.4 at 25 °C and pH7 /Magnevist Injection/

Documented Uses

• ... Gadopentetate dimeglumine (Gd-DTPA, Magnevist..) became commercially available in 1988 and is currently marketed in 101 countries. ... Gd-DTPA has been used in more than 45 million magnetic resonance imaging procedures since 1988 and is currently used globally in more than 5 million applications annually.
• Injectable contrast medium for magnetic resonance imaging (MRI)
• Typical contrast agents are gadolinium-based compounds that possess a higher linear attenuation coefficient than soft tissues. /Contrast agents/
• Magnevist injection is indicated for use with magnetic resonance imaging (MRI) in adults, and pediatric patients (2 years of age and older) to visualize lesions with abnormal vascularity in the brain (intracranial lesions), spine and associated tissues. Magnevist injection has been shown to facilitate visualization of intracranial lesions including but not limited to tumors. /Included in US product labeling/
• Magnevist injection is indicated for use with MRI in adults and pediatric patients (2 years of age and older) to facilitate the visualization of lesions with abnormal vascularity in the head and neck. /Included in US product labeling/
• Magnevist injection is indicated for use in MRI in adults and pediatric patients (2 years of age and older) to facilitate the visualization of lesions with abnormal vascularity in the body. /Included in US product labeling/

Synonyms

Magnevist; Gadopentetic acid dimeglumine salt; Dimeglumine-gadolinium-dtpa; CHEBI:31797; DTXSID70235367; Diethylenetriaminepentaacetic acid dimeglumine salt gadolinium chelate; Diethylenetriaminepenta-acetic Acid, Gadolinium; Magnevist Enteral; Magnograf Enteral; DTPA, Gadolinium; Gd DTPA; RefChem:57348; Dimeglumine, Gadopentetate; Gadolinium DTPA Dimeglumine; Dimeglumine, Gadolinium DTPA; DTXCID70157858

Frequently Asked Questions

What are the CAS number and molecular formula of Gadopentetate dimeglumine?

CAS 86050-77-3; molecular formula C28H54GdN5O20; molecular weight — g/mol.

What other names is Gadopentetate dimeglumine known by?

Magnevist, Gadopentetic acid dimeglumine salt, Dimeglumine-gadolinium-dtpa, CHEBI:31797, DTXSID70235367, Diethylenetriaminepentaacetic acid dimeglumine salt gadolinium chelate.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.