estradiol 3-acetate

Independent reference data for estradiol 3-acetate (CAS 4245-41-4), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

Femring is indicated for the treatment of vasomotor and urogenital symptoms associated with menopause. Use of Femring (estradiol acetate) has been shown to improve symptoms caused by atrophy of the vagina (such as dryness, burning, pruritus and dyspareunia) and/or the lower urinary tract (urinary urgency and dysuria).Exercise caution with grapefruit products. Grapefruit inhibits CYP3A4 metabolism, which may increase the serum concentration of estradiol acetate.

Synonyms and trade names

Estradiol acetate; 4245-41-4; Femring; Femtrace; Estradiol 3-acetate; Estradiol-3-acetate; Menoring; 3-O-Acetylestradiol; 17beta-Estradiol 3-acetate; Estradiol, 3-acetate; DTXSID7045867; beta-Estradiol 3-acetate; UNII-5R97F5H93P; E 3A; 5R97F5H93P; DTXCID5025867

GHS hazard classification

Reported hazard statements	H351 (96.2%), H360 (100%), H362 (96.2%)

H351 (96.2%): Suspected of causing cancer [Warning Carcinogenicity]

H360 (100%): May damage fertility or the unborn child [Danger Reproductive toxicity]

What the public record says

estradiol 3-acetate · CAS 4245-41-4 · C20H26O3. UNII 5R97F5H93P. Collision Cross Section: 185.16 Ų [M-H]-.

Source: PubChem / Wikidata; the batch COA governs where values differ.