N-(2-diethylaminopropyl)-phenothiazine hydrochloride

Independent reference data for N-(2-diethylaminopropyl)-phenothiazine hydrochloride (CAS 1094-08-2), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

Profenamine is indicated in the symptomatic treatment of drug-induced extrapyramidal reactions and of the manifestations (rigidity, akinesia, sialorrhea, oculogyric crisis, tremor, etc.) of Parkinson's disease of encephalitic, arteriosclerotic or idiopathic origin. It is also used to control severe reactions to certain medicines such as reserpine.Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only.

Synonyms and trade names

ethopropazine; Profenamine; Ethopromazine; 522-00-9; Profenaminum; Profenamina; 2-Diethylamino-1-propyl-N-dibenzoparathiazine; N,N-Diethyl-alpha-methyl-10H-phenothiazine-10-ethanamine; W-483; RP-3356; SC-2538; 7WI4P02YN1; (+-)-Ethopropazine; 10-[2-(Diethylamino)propyl]phenothiazine; 10-[2-(Diethylamino)-1-Propyl]phenothiazine; 10H-Phenothiazine-10-ethanamine, N,N-diethyl-alpha-methyl-

What the public record says

ethopropazine hydrochloride · CAS 1094-08-2 · C19H24N2S. UNII 7WI4P02YN1. Melting Point: 166-168; Melting Point: 64.5 °C; Solubility: 0.693.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.