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Cabazitaxel

CAS 183133-96-2C45H57NO14MW 835.9

Cabazitaxel (CAS 183133-96-2) — formula C45H57NO14, molecular weight 835.9; category organic chemicals.

Product Description

Cabazitaxel (CAS 183133-96-2) is a chemical raw material in the organic chemicals category. Its molecular formula C45H57NO14 comprises 45 C, 57 H, 1 N, 14 O atoms. Its molecular weight is about 835.9. Reported physicochemical data: melting point around 170, LogP about 2.7. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number183133-96-2
Molecular FormulaC45H57NO14
Molecular Weight835.9
Melting Point170
LogP2.7
CategoryOrganic Chemicals

Technical Profile

What this product is

Cabazitaxel is a carbon-based organic compound with CAS registry number 183133-96-2 and molecular formula C45H57NO14 (molecular weight 835.9), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 183133-96-2

Its molecular formula C45H57NO14 comprises 45 C, 57 H, 1 N, 14 O atoms.

Also known as: Cabazitaxel · 卡巴他赛

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of Cabazitaxel?

The CAS registry number of Cabazitaxel is 183133-96-2.

What is the molecular formula and molecular weight of Cabazitaxel?

Molecular formula C45H57NO14, molecular weight 835.9.

What other names is Cabazitaxel known by?

It is also registered under: Cabazitaxel, 卡巴他赛.

Which category does Cabazitaxel belong to?

Category: Organic Chemicals.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Cabazitaxel (CAS 183133-96-2), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number183133-96-2
PubChem CID9854073
Molecular formulaC45H57NO14
IUPAC name[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
UNII (FDA)51F690397J

Computed descriptors

Molecular Weight835.9
XLogP32.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count14
Rotatable Bond Count15
Exact Mass835.37790549
Monoisotopic Mass835.37790549
Topological Polar Surface Area202
Heavy Atom Count60

Physicochemical values on record

Melting Point170

Documented uses on record

    Cabazitaxel is indicated, in combination with [prednisone], for the treatment of patients with metastatic castration-resistant prostate cancer previously treated with a [docetaxel]-containing treatment regimen. In Europe and Canada, it can also be used in combination with [prednisolone].Cabazitaxel is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel. Therapy with cabazitaxel has been associated with a low rate of serum enzyme elevations, but has not been linked to cases of clinically apparent acute liver injury, although it can cause severe hypersensitivity infusion reactions which in some instances can be associated with acute liver injury.

    Synonyms and trade names

    CABAZITAXEL; 183133-96-2; Jevtana; Taxoid XRP6258; Xrp6258; Cabazitaxelum; TXD 258; XRP-6258; Jevtana Kit; TXD258; Cabazitaxel Injection; XRP 6258; kabazitaxel; NSC-761432; TXD-258; 51F690397J

    GHS hazard classification

    Reported hazard statementsH302 (85.7%), H311 (42.9%), H315 (85.7%), H317 (14.3%), H318 (14.3%), H335 (14.3%), H341 (85.7%), H360 (57.1%)

    H302 (85.7%): Harmful if swallowed [Warning Acute toxicity, oral]

    H311 (42.9%): Toxic in contact with skin [Danger Acute toxicity, dermal]

    What the public record says

    Cabazitaxel · CAS 183133-96-2 · C45H57NO14. UNII 51F690397J. Melting Point: 170.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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Supplier: Jinan Shenghe Chemical Co., Ltd.

中文页面: 卡巴他赛

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