(S)-2-氨基-3-(4-羟基苯基)丙酸

Description

(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid · CAS 25619-78-7 · C9H11NO3. UNII 42HK56048U. Melting Point: 343; Melting Point: 344 °C; Melting Point: 343 °C.

Identification

CAS Registry Number	25619-78-7
PubChem CID	6057
Molecular formula	C9H11NO3
IUPAC name	(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid
UNII (FDA)	42HK56048U
FEMA number	3736
JECFA number	1434

Computed Descriptors

Molecular Weight	181.19
XLogP3	-2.3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	181.07389321
Monoisotopic Mass	181.07389321
Topological Polar Surface Area	83.6
Heavy Atom Count	13
Formal Charge	0

Physical & Chemical Properties

Melting Point	343
Melting Point	344 °C
Melting Point	343 °C
Solubility	479
Solubility	0.479 mg/mL
LogP	-2.26
LogP	log Kow= 2.26
Ionization Efficiency	2.51
Ionization Efficiency	2.7
Ionization Efficiency	MeCN (80%)

Physical description & handling notes

• Large Crystals
• Solid; [Merck Index] White fine crystals and fragments; [Sigma-Aldrich MSDS]
• Solid
• Colourless silky needles or white crystalline powder; odourless
• FINE SILKY NEEDLES
• White crystals

Regulatory Status

Regulatory & Food Contact	EU Flavoring substances FDA Substance added to food: FLAVORING AGENT OR ADJUVANT, NUTRIENT SUPPLEMENT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent No safety concern at current levels of intake when used as a flavouring agent TRS 928-JECFA 63/98
GHS notification summary	84.3% (226 / 268)

GHS Hazard Classification

GHS notification summary	84.3% (226 / 268)
Reported hazard statements	H315 (14.9%), H319 (14.9%), H335 (14.6%)

Documented Uses

• Non-essential amino acid; Used in biochemical research; [Merck Index] Used as a flavoring agent and nutritional supplement; [FDA]
• NUTRIENT &/OR DIETARY SUPPLEMENT
• Use (kg; approx.) in Germany (2009): >750
• Consumption (g per capita; approx.) in Germany (2009): 0.00916
• Tyrosine is claimed to act as an effective antidepressant, however results are mixed. Tyrosine has also been claimed to reduce stress and combat narcolepsy and chronic fatigue, however these claims have been refuted by some studies.
• Flavoring Agents -> JECFA Flavorings Index

Synonyms

L-tyrosine; tyrosine; 60-18-4; (S)-Tyrosine; (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid; p-Tyrosine; L-p-Tyrosine; 4-Hydroxy-L-phenylalanine; tirosina; Tyrosinum; L-Phenylalanine, 4-hydroxy-; beta-(p-Hydroxyphenyl)alanine; (-)-alpha-Amino-p-hydroxyhydrocinnamic acid; FEMA No. 3736; (S)-alpha-Amino-4-hydroxybenzenepropanoic acid; (S)-(-)-Tyrosine

Frequently Asked Questions

What are the CAS number and molecular formula of (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid?

CAS 25619-78-7; molecular formula C9H11NO3; molecular weight — g/mol.

What other names is (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid known by?

L-tyrosine, tyrosine, 60-18-4, (S)-Tyrosine, (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid, p-Tyrosine.

What is the regulatory status of (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid?

Documented regulatory listings: EU Flavoring substances; FDA Substance added to food: FLAVORING AGENT OR ADJUVANT, NUTRIENT SUPPLEMENT; Flavoring Agents.

Is (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid classified as hazardous?

84.3% of GHS notifications report no hazard classification (226 of 268).

What are the key physical properties of (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid?

Melting Point: 343; Melting Point: 344 °C; Melting Point: 343 °C; Solubility: 479.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.