Triethylene glycol

Description

Triethylene glycol · CAS 112-27-6 · C6H14O4. UNII 3P5SU53360. Boiling Point: 545 °F at 760 mmHg (NTP, 1992); Boiling Point: 285 °C; 165 °C at 14 mm Hg; Boiling Point: 285 °C.

Identification

CAS Registry Number	112-27-6
PubChem CID	8172
Molecular formula	C6H14O4
IUPAC name	2-[2-(2-hydroxyethoxy)ethoxy]ethanol
UNII (FDA)	3P5SU53360

Computed Descriptors

Molecular Weight	150.17
XLogP3	-1.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	150.08920892
Monoisotopic Mass	150.08920892
Topological Polar Surface Area	58.9
Heavy Atom Count	10
Formal Charge	0

Physical & Chemical Properties

Boiling Point	545 °F at 760 mmHg (NTP, 1992)
Boiling Point	285 °C; 165 °C at 14 mm Hg
Boiling Point	285 °C
Boiling Point	285 °C @760 [mm Hg]
Melting Point	24.3 °F (NTP, 1992)
Melting Point	-7 °C
Melting Point	-5 - -7 °C
Melting Point	-4.3 °C
Flash Point	330 °F (NTP, 1992)
Flash Point	165 °C

Physical description & handling notes

• Triethylene glycol is a colorless liquid with a mild odor. Dense than water. (USCG, 1999)
• CBI; Liquid
• Colorless, hygroscopic liquid that is nearly odorless; [Merck Index] Colorless clear viscous liquid with no odor; [MSDSonline]
• COLOURLESS HYGROSCOPIC LIQUID.
• Colorless liquid
• Practically odorless

Regulatory Status

Regulatory & Food Contact	FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS CIR / INCI: Cosmetic ingredients (Triethylene Glycol) -> CIR (Cosmetic Ingredient Review)
GHS notification summary	97.2% (2397 / 2467)

GHS Hazard Classification

GHS notification summary	97.2% (2397 / 2467)
Reported hazard statements	H335

Documented Uses

• CIR ingredient: Triethylene Glycol
• Using Disinfectants or Biocides [Category: Clean]
• Textiles (Printing, Dyeing, or Finishing) [Category: Industry]
• Triethylene glycol is approved by the Food and Drug Administration (FDA) as a preservative for food packaging adhesives ... . Currently, however, there are no EPA registered products for this use. Triethylene glycol /is also approved as/ an indirect food additive for its use as a plasticizer in cellophane.
• For more Uses (Complete) data for TRIETHYLENE GLYCOL (12 total), please visit the HSDB record page.
• EPA Safer Chemical Functional Use Classes -> Solvents

Synonyms

TRIETHYLENE GLYCOL; 112-27-6; Triglycol; 2,2'-(Ethane-1,2-diylbis(oxy))diethanol; 2,2'-Ethylenedioxydiethanol; 2-[2-(2-Hydroxyethoxy)ethoxy]ethanol; Trigen; Triethylenglykol; Triethyleneglycol; 1,2-Bis(2-hydroxyethoxy)ethane; 2,2'-Ethylenedioxybis(ethanol); 3,6-Dioxaoctane-1,8-diol; 2,2'-(Ethylenedioxy)diethanol; 2,2'-Ethylenedioxyethanol; Di-beta-hydroxyethoxyethane; Glycol bis(hydroxyethyl) ether

Frequently Asked Questions

What are the CAS number and molecular formula of Triethylene glycol?

CAS 112-27-6; molecular formula C6H14O4; molecular weight — g/mol.

What other names is Triethylene glycol known by?

TRIETHYLENE GLYCOL, 112-27-6, Triglycol, 2,2'-(Ethane-1,2-diylbis(oxy))diethanol, 2,2'-Ethylenedioxydiethanol, 2-[2-(2-Hydroxyethoxy)ethoxy]ethanol.

What is the regulatory status of Triethylene glycol?

Documented regulatory listings: FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS; CIR / INCI: Cosmetic ingredients (Triethylene Glycol) -> CIR (Cosmetic Ingredient Review).

Is Triethylene glycol classified as hazardous?

97.2% of GHS notifications report no hazard classification (2397 of 2467).

What are the key physical properties of Triethylene glycol?

Boiling Point: 545 °F at 760 mmHg (NTP, 1992); Boiling Point: 285 °C; 165 °C at 14 mm Hg; Boiling Point: 285 °C; Boiling Point: 285 °C @760 [mm Hg].

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.