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Glyoxylic acid

CAS 298-12-4C2H2O3MW 74.04

Glyoxylic acid (CAS 298-12-4) — formula C2H2O3, molecular weight 74.04; category organic chemicals.

Product Overview

CAS Number298-12-4
Molecular FormulaC2H2O3
Molecular Weight74.04
Melting Point98
LogPlog Kow= -0.07
ApplicationsUses: Found in unripe fruit, young green leaves, and very young sugar beets, [Merck Index] Used to make flavorings, perfumes, cosmetics, pharmaceuticals, dyes, plastics, agricultural chemicals, and vanillin, Also used as a cleaning agent for a variety of industrial applications, [HSDB], INTERMEDIATE FOR FLAVORINGS, PERFUMES, PHARMACEUTICALS, DYES, PLASTICS, AGRICULTURAL CHEMICALS., Cleaning agent for a variety of industrial applications, as a speciality chemical and biodegradable copolymer feedstock., Ingredient in cosmetics, CHEM INT FOR ITS ESTERS-EG, METHYL ESTER (PESTICIDE INT), CHEM INT FOR VANILLIN, Use Classification: Cosmetics -> Buffering, Industry Uses: Other, Intermediate, Corrosion inhibitor, Not Known or Reasonably Ascertainable, Consumer Uses: Not Known or Reasonably Ascertainable, Household Products: Information on 3 consumer products that contain Glyoxylic Acid in the following categories is provided:, • Personal Care, Methods of Manufacturing: Prepd by heating dibromoacetic acid with some water, by electrolytic reduction of oxalic acid, by action of Aspergillus niger on calcium acetate, malonic or citric acid., Formulations, Preparations: SUPPLIED AS A 50% SOLN ... ., U.S. Production: 2023: 1, 000, 000 - <5, 000 lb, 2022: 5, 000 - <10, 2021: 10, 000 - <50, 2020: 5, (1977) NO EVIDENCE OF COMMERCIAL PRODN IN U.S., (1981) NO EVIDENCE OF COMMERCIAL PRODN IN U.S., General Manufacturing Information: Not Known or Reasonably Ascertainable, All Other Basic Organic Chemical Manufacturing, Oil and Gas Drilling, Extraction, and Support activities, Acetic acid, 2-oxo-: ACTIVE, PATIENTS SUFFERING FROM PRIMARY HYPEROXALURIA SHOW ELEVATED PLASMA CONCN OF OXALIC ACID & GLYOXYLIC ACID. IN VITRO ADSORPTION OF THESE CMPD INTO VARIOUS SUBSTANCES WAS INVESTIGATED. HYDROUS ZIRCONIUM OXIDE WAS MOST EFFECTIVE SORBENT STUDIED FOR REMOVAL OF OXALIC ACID & GLYOXYLIC ACID. IN BATCH EXPT, ZIRCONIUM OXIDE WAS CAPABLE OF BINDING 5.5 UMOL OXALIC ACID & 8 UMOL OF GLYOXYLIC ACID, G SORBENT USING 0.5 G SORBENT, L & IONIC COMPOSITION RESEMBLING THAT OF PLASMA. RECIRCULATION OF 2 L OF THE SAME SOLN THROUGH 12 G OF MIXT OF HYDROUS ZIRCONIUM OXIDE & ALUMINA FOR 6 HR AT FLOW RATE OF 12 ML, MIN, RESULTED IN FINAL CONCN OF 70 UMOL, L OF OXALIC ACID & 50 UMOL, L OF GLYOXYLIC ACID.
CategoryOrganic Chemicals

Applications

Documented applications: Uses: Found in unripe fruit, young green leaves, and very young sugar beets, [Merck Index] Used to make flavorings, perfumes, cosmetics, pharmaceuticals, dyes, plastics, agricultural chemicals, and vanillin, Also used as a cleaning agent for a variety of industrial applications, [HSDB], INTERMEDIATE FOR FLAVORINGS, PERFUMES, PHARMACEUTICALS, DYES, PLASTICS, AGRICULTURAL CHEMICALS., Cleaning agent for a variety of industrial applications, as a speciality chemical and biodegradable copolymer feedstock., Ingredient in cosmetics, CHEM INT FOR ITS ESTERS-EG, METHYL ESTER (PESTICIDE INT), CHEM INT FOR VANILLIN, Use Classification: Cosmetics -> Buffering, Industry Uses: Other, Intermediate, Corrosion inhibitor, Not Known or Reasonably Ascertainable, Consumer Uses: Not Known or Reasonably Ascertainable, Household Products: Information on 3 consumer products that contain Glyoxylic Acid in the following categories is provided:, • Personal Care, Methods of Manufacturing: Prepd by heating dibromoacetic acid with some water, by electrolytic reduction of oxalic acid, by action of Aspergillus niger on calcium acetate, malonic or citric acid., Formulations, Preparations: SUPPLIED AS A 50% SOLN ... ., U.S. Production: 2023: 1, 000, 000 - <5, 000 lb, 2022: 5, 000 - <10, 2021: 10, 000 - <50, 2020: 5, (1977) NO EVIDENCE OF COMMERCIAL PRODN IN U.S., (1981) NO EVIDENCE OF COMMERCIAL PRODN IN U.S., General Manufacturing Information: Not Known or Reasonably Ascertainable, All Other Basic Organic Chemical Manufacturing, Oil and Gas Drilling, Extraction, and Support activities, Acetic acid, 2-oxo-: ACTIVE, PATIENTS SUFFERING FROM PRIMARY HYPEROXALURIA SHOW ELEVATED PLASMA CONCN OF OXALIC ACID & GLYOXYLIC ACID. IN VITRO ADSORPTION OF THESE CMPD INTO VARIOUS SUBSTANCES WAS INVESTIGATED. HYDROUS ZIRCONIUM OXIDE WAS MOST EFFECTIVE SORBENT STUDIED FOR REMOVAL OF OXALIC ACID & GLYOXYLIC ACID. IN BATCH EXPT, ZIRCONIUM OXIDE WAS CAPABLE OF BINDING 5.5 UMOL OXALIC ACID & 8 UMOL OF GLYOXYLIC ACID, G SORBENT USING 0.5 G SORBENT, L & IONIC COMPOSITION RESEMBLING THAT OF PLASMA. RECIRCULATION OF 2 L OF THE SAME SOLN THROUGH 12 G OF MIXT OF HYDROUS ZIRCONIUM OXIDE & ALUMINA FOR 6 HR AT FLOW RATE OF 12 ML, MIN, RESULTED IN FINAL CONCN OF 70 UMOL, L OF OXALIC ACID & 50 UMOL, L OF GLYOXYLIC ACID..

Technical Profile

What this product is

Glyoxylic acid is a carbon-based organic compound with CAS registry number 298-12-4 and molecular formula C2H2O3 (molecular weight 74.04), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 298-12-4

Its molecular formula C2H2O3 comprises 2 C, 2 H, 3 O atoms.

Also known as: Glyoxylic acid · 乙醛酸

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of Glyoxylic acid?

The CAS registry number of Glyoxylic acid is 298-12-4.

What is the molecular formula and molecular weight of Glyoxylic acid?

Molecular formula C2H2O3, molecular weight 74.04.

What other names is Glyoxylic acid known by?

It is also registered under: Glyoxylic acid, 乙醛酸.

What are the documented applications of Glyoxylic acid?

Recorded applications: Uses: Found in unripe fruit, young green leaves, and very young sugar beets, [Merck Index] Used to make flavorings, perfumes, cosmetics, pharmaceuticals, dyes, plastics, agricultural chemicals, and vanillin, Also used as a cleaning agent for a variety of industrial applications, [HSDB], INTERMEDIATE FOR FLAVORINGS, PERFUMES, PHARMACEUTICALS, DYES, PLASTICS, AGRICULTURAL CHEMICALS., Cleaning agent for a variety of industrial applications, as a speciality chemical and biodegradable copolymer feedstock., Ingredient in cosmetics, CHEM INT FOR ITS ESTERS-EG, METHYL ESTER (PESTICIDE INT), CHEM INT FOR VANILLIN, Use Classification: Cosmetics -> Buffering, Industry Uses: Other, Intermediate, Corrosion inhibitor, Not Known or Reasonably Ascertainable, Consumer Uses: Not Known or Reasonably Ascertainable, Household Products: Information on 3 consumer products that contain Glyoxylic Acid in the following categories is provided:, • Personal Care, Methods of Manufacturing: Prepd by heating dibromoacetic acid with some water, by electrolytic reduction of oxalic acid, by action of Aspergillus niger on calcium acetate, malonic or citric acid., Formulations, Preparations: SUPPLIED AS A 50% SOLN ... ., U.S. Production: 2023: 1, 000, 000 - <5, 000 lb, 2022: 5, 000 - <10, 2021: 10, 000 - <50, 2020: 5, (1977) NO EVIDENCE OF COMMERCIAL PRODN IN U.S., (1981) NO EVIDENCE OF COMMERCIAL PRODN IN U.S., General Manufacturing Information: Not Known or Reasonably Ascertainable, All Other Basic Organic Chemical Manufacturing, Oil and Gas Drilling, Extraction, and Support activities, Acetic acid, 2-oxo-: ACTIVE, PATIENTS SUFFERING FROM PRIMARY HYPEROXALURIA SHOW ELEVATED PLASMA CONCN OF OXALIC ACID & GLYOXYLIC ACID. IN VITRO ADSORPTION OF THESE CMPD INTO VARIOUS SUBSTANCES WAS INVESTIGATED. HYDROUS ZIRCONIUM OXIDE WAS MOST EFFECTIVE SORBENT STUDIED FOR REMOVAL OF OXALIC ACID & GLYOXYLIC ACID. IN BATCH EXPT, ZIRCONIUM OXIDE WAS CAPABLE OF BINDING 5.5 UMOL OXALIC ACID & 8 UMOL OF GLYOXYLIC ACID, G SORBENT USING 0.5 G SORBENT, L & IONIC COMPOSITION RESEMBLING THAT OF PLASMA. RECIRCULATION OF 2 L OF THE SAME SOLN THROUGH 12 G OF MIXT OF HYDROUS ZIRCONIUM OXIDE & ALUMINA FOR 6 HR AT FLOW RATE OF 12 ML, MIN, RESULTED IN FINAL CONCN OF 70 UMOL, L OF OXALIC ACID & 50 UMOL, L OF GLYOXYLIC ACID..

Which category does Glyoxylic acid belong to?

Category: Organic Chemicals.

PubChem Public Data

Independent reference data for Glyoxylic acid (CAS 298-12-4), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number298-12-4
PubChem CID760
Molecular formulaC2H2O3
IUPAC nameoxaldehydic acid
UNII (FDA)JQ39C92HH6

Computed descriptors

Molecular Weight74.04
XLogP3-0.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass74.000393922
Monoisotopic Mass74.000393922
Topological Polar Surface Area54.4
Heavy Atom Count5

Physicochemical values on record

Melting Point98
Melting Point98 °C
Melting Point-93 °C
Density1.42 @ 20 °C/4 °C
Vapor Pressure1.06 [mmHg]
LogPlog Kow= -0.07
Dissociation Constants3.3 (at 25 °C)
Dissociation ConstantspKa = 3.30 @ 25 °C
Formulations/PreparationsSUPPLIED AS A 50% SOLN ... .

Documented uses on record

    Found in unripe fruit, young green leaves, and very young sugar beets; [Merck Index] Used to make flavorings, perfumes, cosmetics, pharmaceuticals, dyes, plastics, agricultural chemicals, and vanillin; Also used as a cleaning agent for a variety of industrial applications; [HSDB]INTERMEDIATE FOR FLAVORINGS, PERFUMES, PHARMACEUTICALS, DYES, PLASTICS, AGRICULTURAL CHEMICALS.

    Synonyms and trade names

    glyoxylic acid; 298-12-4; 2-Oxoacetic Acid; Glyoxalic acid; Oxoacetic acid; Oxoethanoic acid; Formylformic acid; Acetic acid, oxo-; Oxalaldehydic acid; oxaldehydic acid; glyoxylate; alpha-Ketoacetic acid; Formic acid, formyl-; glyoxalate; Kyselina glyoxylova; JQ39C92HH6

    GHS hazard classification

    Reported hazard statementsH317, H318, H290 (60.6%), H319

    H317: May cause an allergic skin reaction [Warning Sensitization, Skin]

    H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

    What the public record says

    Glyoxylic acid · CAS 298-12-4 · C2H2O3. UNII JQ39C92HH6. Melting Point: 98; Melting Point: 98 °C; Melting Point: -93 °C.

    Physical description and handling notes

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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