Cromoglycic Acid

Description

Cromoglycic Acid · CAS 16110-51-3 · C23H16O11. UNII Y0TK0FS77W. Melting Point: 241; Melting Point: 241-242 °C (decomposes); Melting Point: 241 - 242 °C.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Solid
• Colorless crystals from ethanol + ether
• WHITE OR CREAMY-WHITE POWDER; MP: 241-242 °C (DECOMPOSES)
• ODORLESS; HYGROSCOPIC; TASTELESS BUT WITH SLIGHTLY BITTER AFTERTASTE; MELTS @ ABOUT 261 °C; INSOL IN ORG SOLVENTS; DOES NOT EXHIBIT POLYMORPHISM; PKA DIFFICULT TO MEASURE BUT BELIEVED BY ANALOGY WITH SIMILAR MONOCHROMES TO BE ABOUT 1.5 TO 2; SOME DEGRADATION PRODUCTS CAN BE DETECTED AFTER PROLONGED EXPOSURE TO UV LIGHT; UNSTABLE IN ALKALINE SOLN /CROMOLYN DISODIUM/
• 100 MG SOL IN 1 ML WATER @ 20 °C; PRACTICALLY INSOL IN CHLOROFORM & ALCOHOL /CROMOLYN DISODIUM/
• VERY STABLE WITH NO DEGRADATION UNDER NORMAL STORAGE CONDITIONS EXCEPT FOR MOISTURE GAIN /DISODIUM/

Documented Uses

• Use (kg; approx.) in Germany (2009): >750
• Consumption (g per capita; approx.) in Germany (2009): 0.00916
• 2,6-DIHYDROXYACETOPHENONE /REACTS/ WITH EPICHLOROHYDRIN IN PRESENCE OF BASIC CATALYST TO YIELD... 2'2'''-((2-HYDROXYTRIMETHYLENE)DIOXY)BIS(6'-HYDROXYACETOPHENONE). REACTION WITH DIETHYL OXALATE EFFECTS DEHYDRATION & DEETHANOLATION OF EACH HYDROXYACETOPHENONE PORTION.../ETHYL ESTERS ARE/...SAPONIFIED WITH NAOH. /2NA/
• 2,6-Dihydroxyacetaphenone + epichlorohydrin + diethyl oxalate (epoxidation/ether formation/condensation/saponification)
• US PATENT 3,419,578. /CROMOLYN DISODIUM/
• Available commercially as the disodium salt.

Synonyms

cromolyn; Cromoglicic acid; 16110-51-3; Cromoglycic acid; Cromoglicate; Acido cromoglicico; Acide cromoglicique; Acidum cromoglicicum; Cromo-Comod; 5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylic acid; Y0TK0FS77W; 1,3-Bis(2-carboxychromon-5-yloxy)-2-hydroxypropane; R03BC01; DTXSID4022860; CHEBI:59773; 1,3-Di(2-carboxy-4-oxochromen-5-yloxy)propan-2-ol

Frequently Asked Questions

What are the CAS number and molecular formula of Cromoglycic Acid?

CAS 16110-51-3; molecular formula C23H16O11; molecular weight — g/mol.

What other names is Cromoglycic Acid known by?

cromolyn, Cromoglicic acid, 16110-51-3, Cromoglycic acid, Cromoglicate, Acido cromoglicico.

What are the key physical properties of Cromoglycic Acid?

Melting Point: 241; Melting Point: 241-242 °C (decomposes); Melting Point: 241 - 242 °C; Solubility: 210.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.