Calcium gluconate monohydrate (CAS 18016-24-5) — formula C12H22CaO14, molecular weight 430.37; category inorganic chemicals.
| CAS Number | 18016-24-5 |
|---|---|
| Molecular Formula | C12H22CaO14 |
| Molecular Weight | 430.37 |
| Melting Point | 120 °C |
| Applications | Uses: CIR ingredient: Calcium Gluconate, Used in sewage purification, coffee processing (anti-caking agent), and food and drugs (sequestering, buffering, and gelling agent), Also has veterinary use for hypocalcemic conditions, [HSDB] Used for industrial cleaning, metal surface treatment, textile bleach stabilizing, aluminum processing, and as a chelating agent in cement set retarding, cleaning products, personal care products, pharmaceuticals, and foods, Also used as a calcium supplement in injection solutions, [OECD SIDS: Gluconic acid and its derivatives - 2004], Aluminum Producing [Category: Industry], Acid and Alkali Cleaning of Metals [Category: Clean], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Sewer and Wastewater Treatment [Category: Industry], Cement Producing [Category: Industry], In sewage purification, in coffee powders to prevent caking, A sequestering agent, food additive, as buffer, in vitamin tablets, Gelling agent in foods, sequestrant in foods, misc uses as a food additive, THERAP CAT (vet): In hypocalcemic states, including bovine milk fever, For more Uses (Complete) data for CALCIUM GLUCONATE (7 total), please visit the HSDB record page., Use Classification: EPA Safer Chemical Functional Use Classes -> Skin Conditioning Agents, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Food Additives -> ACIDITY_REGULATOR, FIRMING_AGENT, NUTRIENT_SUPPLEMENT, SEQUESTRANT -> JECFA Functional Classes, Cosmetics -> Oral care, Humectant, Household Products: Information on 6 consumer products that contain Calcium Gluconate in the following categories is provided:, • Personal Care, Methods of Manufacturing: Neutralization of gluconic acid with lime or calcium carbonate., D-Glucose is oxidized to gluconic acid in the presence of calcium carbonate. The oxidation may be effected by certain molds, eg, Aspergillus niger, or by bromine., Formulations, Preparations: Calcium gluconate, USP ... contains 9% calcium ... Available as calcium gluconate tablets, USP, containing 325, 500, 650, or 1000 mg of the salt ... for im and iv injection, calcium gluconate injection, admin as 10% soln (0.45 mEq Ca++, mL)., Grades: technical, FCC, special for ampules., Due to its limited solubility, calcium gluconate must frequently be suspended in liquid mixtures and tragacanth is useful as a suspending agent., Calcium gluconate injection:a 10% soln, 9.3 mg of Ca+2, mL ... 10-mL vial, U.S. Production: (1971) 2.97X10+8 grams (sales), (1975) Probably greater than 4.54X10+5 grams, U.S. Imports: (1972) 8.13X10+8 grams (Gluconic acid compounds), (1975) 3.24X10+6 g (Gluconic acid compounds), U.S. Exports: (1972) No Data, (1975) No Data, General Manufacturing Information: D-Gluconic acid, calcium salt (2:1): ACTIVE, More concn (20 to 30%) aq soln...obtained by addn of boric acid or similar complex-forming acids. .., ca d-saccharate is used in, prepn of supersaturated injectable soln of calcium gluconate... injectable soln of calcium gluconate containing sodium ascorbate...described...British patent 495, 675 and German 702, 185., Incompatibilities - sol calcium salts are pptd by borates, carbonates, citrates, oxalates, sulfates, and tartrates., Calcium chloride, Incompatibilities of iv additives: cephalothin sodium, magnesium sulfate, novobiocin (albamycin) sodium, prochlorperazine (compazine) edisylate, sodium bicarbonate (dependent on concn of sodium bicarbonate, and calcium). |
| Category | Inorganic Chemicals |
Documented applications: Uses: CIR ingredient: Calcium Gluconate, Used in sewage purification, coffee processing (anti-caking agent), and food and drugs (sequestering, buffering, and gelling agent), Also has veterinary use for hypocalcemic conditions, [HSDB] Used for industrial cleaning, metal surface treatment, textile bleach stabilizing, aluminum processing, and as a chelating agent in cement set retarding, cleaning products, personal care products, pharmaceuticals, and foods, Also used as a calcium supplement in injection solutions, [OECD SIDS: Gluconic acid and its derivatives - 2004], Aluminum Producing [Category: Industry], Acid and Alkali Cleaning of Metals [Category: Clean], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Sewer and Wastewater Treatment [Category: Industry], Cement Producing [Category: Industry], In sewage purification, in coffee powders to prevent caking, A sequestering agent, food additive, as buffer, in vitamin tablets, Gelling agent in foods, sequestrant in foods, misc uses as a food additive, THERAP CAT (vet): In hypocalcemic states, including bovine milk fever, For more Uses (Complete) data for CALCIUM GLUCONATE (7 total), please visit the HSDB record page., Use Classification: EPA Safer Chemical Functional Use Classes -> Skin Conditioning Agents, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Food Additives -> ACIDITY_REGULATOR, FIRMING_AGENT, NUTRIENT_SUPPLEMENT, SEQUESTRANT -> JECFA Functional Classes, Cosmetics -> Oral care, Humectant, Household Products: Information on 6 consumer products that contain Calcium Gluconate in the following categories is provided:, • Personal Care, Methods of Manufacturing: Neutralization of gluconic acid with lime or calcium carbonate., D-Glucose is oxidized to gluconic acid in the presence of calcium carbonate. The oxidation may be effected by certain molds, eg, Aspergillus niger, or by bromine., Formulations, Preparations: Calcium gluconate, USP ... contains 9% calcium ... Available as calcium gluconate tablets, USP, containing 325, 500, 650, or 1000 mg of the salt ... for im and iv injection, calcium gluconate injection, admin as 10% soln (0.45 mEq Ca++, mL)., Grades: technical, FCC, special for ampules., Due to its limited solubility, calcium gluconate must frequently be suspended in liquid mixtures and tragacanth is useful as a suspending agent., Calcium gluconate injection:a 10% soln, 9.3 mg of Ca+2, mL ... 10-mL vial, U.S. Production: (1971) 2.97X10+8 grams (sales), (1975) Probably greater than 4.54X10+5 grams, U.S. Imports: (1972) 8.13X10+8 grams (Gluconic acid compounds), (1975) 3.24X10+6 g (Gluconic acid compounds), U.S. Exports: (1972) No Data, (1975) No Data, General Manufacturing Information: D-Gluconic acid, calcium salt (2:1): ACTIVE, More concn (20 to 30%) aq soln...obtained by addn of boric acid or similar complex-forming acids. .., ca d-saccharate is used in, prepn of supersaturated injectable soln of calcium gluconate... injectable soln of calcium gluconate containing sodium ascorbate...described...British patent 495, 675 and German 702, 185., Incompatibilities - sol calcium salts are pptd by borates, carbonates, citrates, oxalates, sulfates, and tartrates., Calcium chloride, Incompatibilities of iv additives: cephalothin sodium, magnesium sulfate, novobiocin (albamycin) sodium, prochlorperazine (compazine) edisylate, sodium bicarbonate (dependent on concn of sodium bicarbonate, and calcium)..
Calcium gluconate monohydrate is an inorganic compound with CAS registry number 18016-24-5 and molecular formula C12H22CaO14 (molecular weight 430.37), belonging to the inorganic chemicals segment of chemical raw materials.
CAS number: 18016-24-5
Its molecular formula C12H22CaO14 comprises 12 C, 22 H, 1 Ca, 14 O atoms.
Also known as: Calcium gluconate monohydrate · 一水葡萄糖酸钙
Category: inorganic chemicals
The CAS registry number of Calcium gluconate monohydrate is 18016-24-5.
Molecular formula C12H22CaO14, molecular weight 430.37.
It is also registered under: Calcium gluconate monohydrate, 一水葡萄糖酸钙.
Recorded applications: Uses: CIR ingredient: Calcium Gluconate, Used in sewage purification, coffee processing (anti-caking agent), and food and drugs (sequestering, buffering, and gelling agent), Also has veterinary use for hypocalcemic conditions, [HSDB] Used for industrial cleaning, metal surface treatment, textile bleach stabilizing, aluminum processing, and as a chelating agent in cement set retarding, cleaning products, personal care products, pharmaceuticals, and foods, Also used as a calcium supplement in injection solutions, [OECD SIDS: Gluconic acid and its derivatives - 2004], Aluminum Producing [Category: Industry], Acid and Alkali Cleaning of Metals [Category: Clean], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Sewer and Wastewater Treatment [Category: Industry], Cement Producing [Category: Industry], In sewage purification, in coffee powders to prevent caking, A sequestering agent, food additive, as buffer, in vitamin tablets, Gelling agent in foods, sequestrant in foods, misc uses as a food additive, THERAP CAT (vet): In hypocalcemic states, including bovine milk fever, For more Uses (Complete) data for CALCIUM GLUCONATE (7 total), please visit the HSDB record page., Use Classification: EPA Safer Chemical Functional Use Classes -> Skin Conditioning Agents, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Food Additives -> ACIDITY_REGULATOR, FIRMING_AGENT, NUTRIENT_SUPPLEMENT, SEQUESTRANT -> JECFA Functional Classes, Cosmetics -> Oral care, Humectant, Household Products: Information on 6 consumer products that contain Calcium Gluconate in the following categories is provided:, • Personal Care, Methods of Manufacturing: Neutralization of gluconic acid with lime or calcium carbonate., D-Glucose is oxidized to gluconic acid in the presence of calcium carbonate. The oxidation may be effected by certain molds, eg, Aspergillus niger, or by bromine., Formulations, Preparations: Calcium gluconate, USP ... contains 9% calcium ... Available as calcium gluconate tablets, USP, containing 325, 500, 650, or 1000 mg of the salt ... for im and iv injection, calcium gluconate injection, admin as 10% soln (0.45 mEq Ca++, mL)., Grades: technical, FCC, special for ampules., Due to its limited solubility, calcium gluconate must frequently be suspended in liquid mixtures and tragacanth is useful as a suspending agent., Calcium gluconate injection:a 10% soln, 9.3 mg of Ca+2, mL ... 10-mL vial, U.S. Production: (1971) 2.97X10+8 grams (sales), (1975) Probably greater than 4.54X10+5 grams, U.S. Imports: (1972) 8.13X10+8 grams (Gluconic acid compounds), (1975) 3.24X10+6 g (Gluconic acid compounds), U.S. Exports: (1972) No Data, (1975) No Data, General Manufacturing Information: D-Gluconic acid, calcium salt (2:1): ACTIVE, More concn (20 to 30%) aq soln...obtained by addn of boric acid or similar complex-forming acids. .., ca d-saccharate is used in, prepn of supersaturated injectable soln of calcium gluconate... injectable soln of calcium gluconate containing sodium ascorbate...described...British patent 495, 675 and German 702, 185., Incompatibilities - sol calcium salts are pptd by borates, carbonates, citrates, oxalates, sulfates, and tartrates., Calcium chloride, Incompatibilities of iv additives: cephalothin sodium, magnesium sulfate, novobiocin (albamycin) sodium, prochlorperazine (compazine) edisylate, sodium bicarbonate (dependent on concn of sodium bicarbonate, and calcium)..
Category: Inorganic Chemicals.
Independent reference data for Calcium gluconate monohydrate (CAS 18016-24-5), compiled from public chemistry databases.
| CAS Registry Number | 18016-24-5 |
|---|---|
| PubChem CID | 9290 |
| Molecular formula | C12H22CaO14 |
| IUPAC name | calcium bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) |
| UNII (FDA) | SQE6VB453K |
| Molecular Weight | 430.37 |
|---|---|
| Hydrogen Bond Donor Count | 10 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 8 |
| Exact Mass | 430.0635462 |
| Monoisotopic Mass | 430.0635462 |
| Topological Polar Surface Area | 283 |
| Heavy Atom Count | 27 |
| Melting Point | 120 °C |
|---|---|
| Melting Point | 178 °C |
| Solubility | Sol in water 3.3 g/100 cc at 15 °C |
| Solubility | In water, 3.33X10+4 mg/L at 25 °C |
| Density | 0.30-0.65 g/cm³ |
CALCIUM GLUCONATE; 299-28-5; Calcium D-gluconate; D-Gluconic acid, calcium salt (2:1); Calcicol; Calglucon; Calciofon; Calcipur; Calglucol; Dragocal; Glucobiogen; Ebucin; Kalpren; Novocal; Calcarea gluconica; Calcium di-gluconate
| Regulatory & Food Contact | FDA Substance added to food: FIRMING AGENT, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FORMULATION AID, NU ACIDITY_REGULATOR; FIRMING_AGENT; NUTRIENT_SUPPLEMENT; SEQUE: Food Additives FIRMING AGENT, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FORMULATION AID, NUTRIENT SUPPLEMENT, SEQUESTRANT Use in food in general as a source of calcium Scientific procedures FDA has no questions |
|---|---|
| GHS notification summary | 98.6% (68 / 69) |
| GHS notification summary | 98.6% (68 / 69) |
|---|
This chemical does not meet GHS hazard criteria for 98.6% (68 of 69) of all reports.
Reported as not meeting GHS hazard criteria by 68 of 69 companies (only 1.4% companies provided GHS information). For more detailed information, please visit ECHA C&L website.
Calcium gluconate monohydrate · CAS 18016-24-5 · C12H22CaO14. UNII SQE6VB453K. Melting Point: 120 °C; Melting Point: 178 °C; Solubility: Sol in water 3.3 g/100 cc at 15 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 一水葡萄糖酸钙