一水葡萄糖酸钙（CAS 18016-24-5）：分子式 C12H22CaO14、分子量 430.37。
| CAS号 | 18016-24-5 |
|---|---|
| 分子式 | C12H22CaO14 |
| 分子量 | 430.37 |
| 熔点 | 120 °C |
| 应用领域 | Uses: CIR ingredient: Calcium Gluconate、Used in sewage purification、coffee processing (anti-caking agent)、and food and drugs (sequestering、buffering、and gelling agent)、Also has veterinary use for hypocalcemic conditions、[HSDB] Used for industrial cleaning、metal surface treatment、textile bleach stabilizing、aluminum processing、and as a chelating agent in cement set retarding、cleaning products、personal care products、pharmaceuticals、and foods、Also used as a calcium supplement in injection solutions、[OECD SIDS: Gluconic acid and its derivatives - 2004]、Aluminum Producing [Category: Industry]、Acid and Alkali Cleaning of Metals [Category: Clean]、Textiles (Fiber & Fabric Manufacturing) [Category: Industry]、Sewer and Wastewater Treatment [Category: Industry]、Cement Producing [Category: Industry]、In sewage purification、in coffee powders to prevent caking、A sequestering agent、food additive、as buffer、in vitamin tablets、Gelling agent in foods、sequestrant in foods、misc uses as a food additive、THERAP CAT (vet): In hypocalcemic states、including bovine milk fever、For more Uses (Complete) data for CALCIUM GLUCONATE (7 total)、please visit the HSDB record page.、Use Classification: EPA Safer Chemical Functional Use Classes -> Skin Conditioning Agents、Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern、Food Additives -> ACIDITY_REGULATOR、FIRMING_AGENT、NUTRIENT_SUPPLEMENT、SEQUESTRANT -> JECFA Functional Classes、Cosmetics -> Oral care、Humectant、Household Products: Information on 6 consumer products that contain Calcium Gluconate in the following categories is provided:、• Personal Care、Methods of Manufacturing: Neutralization of gluconic acid with lime or calcium carbonate.、D-Glucose is oxidized to gluconic acid in the presence of calcium carbonate. The oxidation may be effected by certain molds、eg、Aspergillus niger、or by bromine.、Formulations、Preparations: Calcium gluconate、USP ... contains 9% calcium ... Available as calcium gluconate tablets、USP、containing 325、500、650、or 1000 mg of the salt ... for im and iv injection、calcium gluconate injection、admin as 10% soln (0.45 mEq Ca++、mL).、Grades: technical、FCC、special for ampules.、Due to its limited solubility、calcium gluconate must frequently be suspended in liquid mixtures and tragacanth is useful as a suspending agent.、Calcium gluconate injection:a 10% soln、9.3 mg of Ca+2、mL ... 10-mL vial、U.S. Production: (1971) 2.97X10+8 grams (sales)、(1975) Probably greater than 4.54X10+5 grams、U.S. Imports: (1972) 8.13X10+8 grams (Gluconic acid compounds)、(1975) 3.24X10+6 g (Gluconic acid compounds)、U.S. Exports: (1972) No Data、(1975) No Data、General Manufacturing Information: D-Gluconic acid、calcium salt (2:1): ACTIVE、More concn (20 to 30%) aq soln...obtained by addn of boric acid or similar complex-forming acids. ..、ca d-saccharate is used in、prepn of supersaturated injectable soln of calcium gluconate... injectable soln of calcium gluconate containing sodium ascorbate...described...British patent 495、675 and German 702、185.、Incompatibilities - sol calcium salts are pptd by borates、carbonates、citrates、oxalates、sulfates、and tartrates.、Calcium chloride、Incompatibilities of iv additives: cephalothin sodium、magnesium sulfate、novobiocin (albamycin) sodium、prochlorperazine (compazine) edisylate、sodium bicarbonate (dependent on concn of sodium bicarbonate、and calcium). |
登记用途：Uses: CIR ingredient: Calcium Gluconate、Used in sewage purification、coffee processing (anti-caking agent)、and food and drugs (sequestering、buffering、and gelling agent)、Also has veterinary use for hypocalcemic conditions、[HSDB] Used for industrial cleaning、metal surface treatment、textile bleach stabilizing、aluminum processing、and as a chelating agent in cement set retarding、cleaning products、personal care products、pharmaceuticals、and foods、Also used as a calcium supplement in injection solutions、[OECD SIDS: Gluconic acid and its derivatives - 2004]、Aluminum Producing [Category: Industry]、Acid and Alkali Cleaning of Metals [Category: Clean]、Textiles (Fiber & Fabric Manufacturing) [Category: Industry]、Sewer and Wastewater Treatment [Category: Industry]、Cement Producing [Category: Industry]、In sewage purification、in coffee powders to prevent caking、A sequestering agent、food additive、as buffer、in vitamin tablets、Gelling agent in foods、sequestrant in foods、misc uses as a food additive、THERAP CAT (vet): In hypocalcemic states、including bovine milk fever、For more Uses (Complete) data for CALCIUM GLUCONATE (7 total)、please visit the HSDB record page.、Use Classification: EPA Safer Chemical Functional Use Classes -> Skin Conditioning Agents、Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern、Food Additives -> ACIDITY_REGULATOR、FIRMING_AGENT、NUTRIENT_SUPPLEMENT、SEQUESTRANT -> JECFA Functional Classes、Cosmetics -> Oral care、Humectant、Household Products: Information on 6 consumer products that contain Calcium Gluconate in the following categories is provided:、• Personal Care、Methods of Manufacturing: Neutralization of gluconic acid with lime or calcium carbonate.、D-Glucose is oxidized to gluconic acid in the presence of calcium carbonate. The oxidation may be effected by certain molds、eg、Aspergillus niger、or by bromine.、Formulations、Preparations: Calcium gluconate、USP ... contains 9% calcium ... Available as calcium gluconate tablets、USP、containing 325、500、650、or 1000 mg of the salt ... for im and iv injection、calcium gluconate injection、admin as 10% soln (0.45 mEq Ca++、mL).、Grades: technical、FCC、special for ampules.、Due to its limited solubility、calcium gluconate must frequently be suspended in liquid mixtures and tragacanth is useful as a suspending agent.、Calcium gluconate injection:a 10% soln、9.3 mg of Ca+2、mL ... 10-mL vial、U.S. Production: (1971) 2.97X10+8 grams (sales)、(1975) Probably greater than 4.54X10+5 grams、U.S. Imports: (1972) 8.13X10+8 grams (Gluconic acid compounds)、(1975) 3.24X10+6 g (Gluconic acid compounds)、U.S. Exports: (1972) No Data、(1975) No Data、General Manufacturing Information: D-Gluconic acid、calcium salt (2:1): ACTIVE、More concn (20 to 30%) aq soln...obtained by addn of boric acid or similar complex-forming acids. ..、ca d-saccharate is used in、prepn of supersaturated injectable soln of calcium gluconate... injectable soln of calcium gluconate containing sodium ascorbate...described...British patent 495、675 and German 702、185.、Incompatibilities - sol calcium salts are pptd by borates、carbonates、citrates、oxalates、sulfates、and tartrates.、Calcium chloride、Incompatibilities of iv additives: cephalothin sodium、magnesium sulfate、novobiocin (albamycin) sodium、prochlorperazine (compazine) edisylate、sodium bicarbonate (dependent on concn of sodium bicarbonate、and calcium).。
一水葡萄糖酸钙 是一种化工化合物，登记 CAS 号为 18016-24-5，分子式 C12H22CaO14（分子量 430.37）。
登记 CAS 号：18016-24-5
其分子式 C12H22CaO14 由 12 个碳、22 个氢、1 个钙、14 个氧 组成。
别名/同义词：一水葡萄糖酸钙 · Calcium gluconate monohydrate
一水葡萄糖酸钙 的 CAS 登记号为 18016-24-5。
分子式 C12H22CaO14，分子量 430.37。
别名/同义词：一水葡萄糖酸钙、Calcium gluconate monohydrate。
登记用途：Uses: CIR ingredient: Calcium Gluconate、Used in sewage purification、coffee processing (anti-caking agent)、and food and drugs (sequestering、buffering、and gelling agent)、Also has veterinary use for hypocalcemic conditions、[HSDB] Used for industrial cleaning、metal surface treatment、textile bleach stabilizing、aluminum processing、and as a chelating agent in cement set retarding、cleaning products、personal care products、pharmaceuticals、and foods、Also used as a calcium supplement in injection solutions、[OECD SIDS: Gluconic acid and its derivatives - 2004]、Aluminum Producing [Category: Industry]、Acid and Alkali Cleaning of Metals [Category: Clean]、Textiles (Fiber & Fabric Manufacturing) [Category: Industry]、Sewer and Wastewater Treatment [Category: Industry]、Cement Producing [Category: Industry]、In sewage purification、in coffee powders to prevent caking、A sequestering agent、food additive、as buffer、in vitamin tablets、Gelling agent in foods、sequestrant in foods、misc uses as a food additive、THERAP CAT (vet): In hypocalcemic states、including bovine milk fever、For more Uses (Complete) data for CALCIUM GLUCONATE (7 total)、please visit the HSDB record page.、Use Classification: EPA Safer Chemical Functional Use Classes -> Skin Conditioning Agents、Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern、Food Additives -> ACIDITY_REGULATOR、FIRMING_AGENT、NUTRIENT_SUPPLEMENT、SEQUESTRANT -> JECFA Functional Classes、Cosmetics -> Oral care、Humectant、Household Products: Information on 6 consumer products that contain Calcium Gluconate in the following categories is provided:、• Personal Care、Methods of Manufacturing: Neutralization of gluconic acid with lime or calcium carbonate.、D-Glucose is oxidized to gluconic acid in the presence of calcium carbonate. The oxidation may be effected by certain molds、eg、Aspergillus niger、or by bromine.、Formulations、Preparations: Calcium gluconate、USP ... contains 9% calcium ... Available as calcium gluconate tablets、USP、containing 325、500、650、or 1000 mg of the salt ... for im and iv injection、calcium gluconate injection、admin as 10% soln (0.45 mEq Ca++、mL).、Grades: technical、FCC、special for ampules.、Due to its limited solubility、calcium gluconate must frequently be suspended in liquid mixtures and tragacanth is useful as a suspending agent.、Calcium gluconate injection:a 10% soln、9.3 mg of Ca+2、mL ... 10-mL vial、U.S. Production: (1971) 2.97X10+8 grams (sales)、(1975) Probably greater than 4.54X10+5 grams、U.S. Imports: (1972) 8.13X10+8 grams (Gluconic acid compounds)、(1975) 3.24X10+6 g (Gluconic acid compounds)、U.S. Exports: (1972) No Data、(1975) No Data、General Manufacturing Information: D-Gluconic acid、calcium salt (2:1): ACTIVE、More concn (20 to 30%) aq soln...obtained by addn of boric acid or similar complex-forming acids. ..、ca d-saccharate is used in、prepn of supersaturated injectable soln of calcium gluconate... injectable soln of calcium gluconate containing sodium ascorbate...described...British patent 495、675 and German 702、185.、Incompatibilities - sol calcium salts are pptd by borates、carbonates、citrates、oxalates、sulfates、and tartrates.、Calcium chloride、Incompatibilities of iv additives: cephalothin sodium、magnesium sulfate、novobiocin (albamycin) sodium、prochlorperazine (compazine) edisylate、sodium bicarbonate (dependent on concn of sodium bicarbonate、and calcium).。
一水葡萄糖酸钙（CAS 18016-24-5）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 18016-24-5 |
|---|---|
| PubChem CID | 9290 |
| Molecular formula | C12H22CaO14 |
| IUPAC name | calcium bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) |
| UNII (FDA) | SQE6VB453K |
| Molecular Weight | 430.37 |
|---|---|
| Hydrogen Bond Donor Count | 10 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 8 |
| Exact Mass | 430.0635462 |
| Monoisotopic Mass | 430.0635462 |
| Topological Polar Surface Area | 283 |
| Heavy Atom Count | 27 |
| Melting Point | 120 °C |
|---|---|
| Melting Point | 178 °C |
| Solubility | Sol in water 3.3 g/100 cc at 15 °C |
| Solubility | In water, 3.33X10+4 mg/L at 25 °C |
| Density | 0.30-0.65 g/cm³ |
CALCIUM GLUCONATE; 299-28-5; Calcium D-gluconate; D-Gluconic acid, calcium salt (2:1); Calcicol; Calglucon; Calciofon; Calcipur; Calglucol; Dragocal; Glucobiogen; Ebucin; Kalpren; Novocal; Calcarea gluconica; Calcium di-gluconate
| Regulatory & Food Contact | FDA Substance added to food: FIRMING AGENT, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FORMULATION AID, NU ACIDITY_REGULATOR; FIRMING_AGENT; NUTRIENT_SUPPLEMENT; SEQUE: Food Additives FIRMING AGENT, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FORMULATION AID, NUTRIENT SUPPLEMENT, SEQUESTRANT Use in food in general as a source of calcium Scientific procedures FDA has no questions |
|---|---|
| GHS notification summary | 98.6% (68 / 69) |
| GHS notification summary | 98.6% (68 / 69) |
|---|
This chemical does not meet GHS hazard criteria for 98.6% (68 of 69) of all reports.
Reported as not meeting GHS hazard criteria by 68 of 69 companies (only 1.4% companies provided GHS information). For more detailed information, please visit ECHA C&L website.
Calcium gluconate monohydrate · CAS 18016-24-5 · C12H22CaO14. UNII SQE6VB453K. Melting Point: 120 °C; Melting Point: 178 °C; Solubility: Sol in water 3.3 g/100 cc at 15 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Calcium gluconate monohydrate