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贝沙罗汀

CAS 153559-49-0C24H28O2MW 348.5

贝沙罗汀(CAS 153559-49-0)属有机化学品类产品,分子式 C24H28O2,分子量 348.5。济南圣和化工有限公司常年现货供应该产品,常规纯度 按批次COA提供(不公开发布),可按客户需求安排分装包装,欢迎邮件或来电询价。

产品概览

CAS号153559-49-0
分子式C24H28O2
分子量348.5
熔点230-231 °C
LogP6.9
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域有机化学品
类别有机化学品

应用领域

有机化学品

贝沙罗汀在有机化学品领域使用广泛。采购前请确认纯度等级与包装形式,以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
运输常规化工运输
样品可协商提供
交期现货/按订单安排

供应说明:贝沙罗汀 常规包装为按订单/批次确认(不公开发布),储存时应密封置于阴凉干燥处,避免与氧化剂混放。济南圣和化工有限公司 支持国内物流发货,大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA(分析证书);可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择 济南圣和化工有限公司 的理由:产品信息透明(含 CAS、分子式、理化参数)、报价响应快(一个工作日内)、单证齐全(COA/MSS/质检资料按需提供)、支持批量与长期协议供货。如需 贝沙罗汀 以外的配套原料,也欢迎一并列出需求清单。

常见问题

贝沙罗汀 的 CAS 号是多少?

贝沙罗汀 的 CAS 号为 153559-49-0。

该产品的纯度和包装规格是什么?

常规纯度规格为 按批次COA提供(不公开发布),包装为 按订单/批次确认(不公开发布),随货提供 COA。

贝沙罗汀 有什么用途?

主要应用于有机化学品。

如何购买或获取报价?

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系,注明产品名称、CAS 号与需求数量,一个工作日内回复报价。供应商:济南圣和化工有限公司。

PubChem 公开数据

Description

Bexarotene · CAS 153559-49-0 · C24H28O2. UNII A61RXM4375. Melting Point: 230-231 °C; Solubility: 1.49e-04 g/L; LogP: 6.9.

Identification

CAS Registry Number153559-49-0
PubChem CID82146
Molecular formulaC24H28O2
IUPAC name4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid
UNII (FDA)A61RXM4375

Computed Descriptors

Molecular Weight348.5
XLogP37.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass348.208930132
Monoisotopic Mass348.208930132
Topological Polar Surface Area37.3
Heavy Atom Count26
Formal Charge0

Physical & Chemical Properties

Melting Point230-231 °C
Solubility1.49e-04 g/L
LogP6.9

Physical description & handling notes

  • Solid
  • Off-white to white powder
  • Insoluble in water and slightly soluble in vegetable oils and ethanol
  • Avoid exposing to high temperatures and humidity after the bottle is opened. Protect from light.
  • 208.7 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID1040619]
  • Also reported as white crystals, mp 234 °C

GHS Hazard Classification

Reported hazard statementsH302 (11.1%), H315 (22.2%), H319 (11.1%), H335 (11.1%), H361 (77.8%), H413 (11.1%)

H302 (11.1%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (22.2%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

  • MESH Heading: Antineoplastic agent
  • Use (kg; approx.) in Germany (2009): >10
  • Consumption (g per capita; approx.) in Germany (2009): 0.000122
  • M.F. Boehm et al., World Intellectual Property Organization patent 9321146 (1993 to Ligand Pharm.); M.L. Dawson et al., US patent 5466861 (1995 to SRI Int.; La Jolla Cancer Res. Found.)
  • Used orally for the treatment of skin manifestations of cutaneous T-cell lymphoma (CTCL) in patients who are refractory to at least one prior systemic therapy. Also used topically for the treatment of skin lesions in early (stage IA and IB) CTCL in patients who experience refractory or persistent disease with the use of other therapies or are intolerant of other therapies.
  • Bexarotene is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL). Bexarotene therapy is associated with a high rate of serum enzyme elevations and rare instances of clinically apparent acute liver injury.

Synonyms

Bexarotene; 153559-49-0; Targretin; Targrexin; LGD1069; LGD-1069; bexaroteno; bexarotenum; LG100069; DTXSID1040619; 4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid; LG-100069; p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid; NSC-747528; A61RXM4375; 4-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)benzoic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Bexarotene?

CAS 153559-49-0; molecular formula C24H28O2; molecular weight — g/mol.

What other names is Bexarotene known by?

Bexarotene, 153559-49-0, Targretin, Targrexin, LGD1069, LGD-1069.

Is Bexarotene classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H361.

What are the key physical properties of Bexarotene?

Melting Point: 230-231 °C; Solubility: 1.49e-04 g/L; LogP: 6.9.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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