磷脂酰丝氨酸

Description

Phosphatidylserine · CAS 1446756-47-3 · C42H82NO10P. UNII 394XK0IH40. LogP: -3.5.

Identification

CAS Registry Number	1446756-47-3
PubChem CID	9547096
Molecular formula	C42H82NO10P
IUPAC name	(2S)-2-amino-3-[[(2R)-2,3-di(octadecanoyloxy)propoxy]-hydroxyphosphoryl]oxypropanoic acid
UNII (FDA)	394XK0IH40

Computed Descriptors

Molecular Weight	792.1
XLogP3	12.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	44
Exact Mass	791.56763481
Monoisotopic Mass	791.56763481
Topological Polar Surface Area	172
Heavy Atom Count	54
Formal Charge	0

Physical & Chemical Properties

LogP	-3.5

Physical description & handling notes

• Solid
• 280.7 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Sample Type: Brain (polar extract); Dataset: Unambiguous Lipids]
• 284.03 Ų [M-H]- [CCS Type: DT; Method: stepped-field]

Regulatory Status

Regulatory & Food Contact	Ingredient in yogurt (excluding fat-free yogurts), powdered milk, ready to drink soymilk, meal replacements, c Scientific procedures FDA has no questions Degussa Food Ingredients GmbH Enzymotec Ltd. CIR / INCI: Cosmetic ingredients (Phosphatidylserine) -> CIR (Cosmetic Ingredient Review)

GHS Hazard Classification

Reported hazard statements	H315 (100%), H319 (100%)

Documented Uses

• CIR ingredient: Phosphatidylserine
• Phosphatidylserine has demonstrated some usefulness in treating cognitive impairment, including Alzheimer's disease, age-associated memory impairment and some non-Alzheimer's dementias. More research is needed before phosphatidylserine can be indicated for immune enhancement or for reduction of exercise stress.
• Absorbed in the small intestine.
• Following absorption, lysophosphatidylserine is metabolized in intestinal mucosa cells, and its metabolites, which include some phosphatidylserine, enter the lymphatics draining the small intestine.
• Phosphatidylcholine Biosynthesis PC(18:0/18:0)
• Phosphatidylethanolamine Biosynthesis PE(18:0/18:0)

Synonyms

Distearoylphosphatidylserine; Phosphotidylserine; 1446756-47-3; 394XK0IH40; (2S)-2-amino-3-[[(2R)-2,3-di(octadecanoyloxy)propoxy]-hydroxyphosphoryl]oxypropanoic acid; Phosphatidyl Serines; Serine, Phosphatidyl; Serines, Phosphatidyl; Serine Phosphoglycerides; Phosphoglycerides, Serine; (2S)-2-amino-3-(((2R)-2,3-di(octadecanoyloxy)propoxy)-hydroxyphosphoryl)oxypropanoic acid; Phospholipid Serine; RefChem:861928; DTXSID401058684; 1,2-Diacyl-sn-glycerol 3-phospho-L-serine; (2S)-2-azaniumyl-3-(((2R)-2,3-di(octadecanoyloxy)propoxy)-hydroxyphosphoryl)oxypropanoate

Frequently Asked Questions

What are the CAS number and molecular formula of Phosphatidylserine?

CAS 1446756-47-3; molecular formula C42H82NO10P; molecular weight — g/mol.

What other names is Phosphatidylserine known by?

Distearoylphosphatidylserine, Phosphotidylserine, 1446756-47-3, 394XK0IH40, (2S)-2-amino-3-[[(2R)-2,3-di(octadecanoyloxy)propoxy]-hydroxyphosphoryl]oxypropanoic acid, Phosphatidyl Serines.

What is the regulatory status of Phosphatidylserine?

Documented regulatory listings: Ingredient in yogurt (excluding fat-free yogurts), powdered milk, ready to drink soymilk, meal replacements, c; Scientific procedures; FDA has no questions.

Is Phosphatidylserine classified as hazardous?

Hazard statements reported: H315, H319.

What are the key physical properties of Phosphatidylserine?

LogP: -3.5.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.