化合物 Rubratoxin A（CAS 22467-31-8）：分子式 C26H32O11、分子量 520.5。
| CAS号 | 22467-31-8 |
|---|---|
| 分子式 | C26H32O11 |
| 分子量 | 520.5 |
| 熔点 | 210-214 °C (dec.) |
| LogP | 1.4 |
| 应用领域 | Uses: Hepatotoxic metabolite from the molds Penicillium rubrum and P. purpurogenum、Often found growing in feedstuffs with Aspergillus sp.、May coexist with aflatoxins、[HSDB]、Rubratoxin A is a mycotoxin produced by fungi such as Penicillum rubrum and Penicillum purpurogenum、which are common soil fungi that sometimes contaminate animal feeds. (A2985、A2988)、Methods of Manufacturing: A STERILE GLUCOSE-MINERAL SALTS BROTH WAS INOCULATED WITH SPORE SUSPENSIONS OR MYCELIAL PELLETS OF PENICILLIUM RUBRUM AND INCUBATED QUIESCENTLY FOR 14 DAYS. RUBRATOXINS WERE RECOVERED FROM CULTURE FILTRATES BY ETHER EXTRACTION AND RESOLVED BY TLC. TOXIN FORMATION WAS ENHANCED BY MALONATE BUT WAS NOT MARKEDLY AFFECTED BY ETHYL MALONATE、SHIKIMATE、AND ACETATE OR BY ISOCITRATE OR OXALOACETATE ADDED IN THE PRESENCE OF MALONATE. CITRATE、CIS-ACONITATE、ALPHA-KETOGLUTARATE、SUCCINATE、FUMARATE AND MALONATE WHEN PRESENT IN THE MEDIUM ALONE OR IN CONJUNCTION WITH MALONATE CAUSED A 15-50% REDUCTION IN RUBRATOXIN FORMATION. ACETYL-COA (10-15 MOL、FLAS) CAUSED AN 80% INCREASE IN TOXIN YIELD. AT 10-3 MOLAR、CITRATE STIMULATED RUBRATOXIN A PRODUCTION BY AS MUCH AS 100%. ABOVE 10-3 MOLAR、CITRATE INHIBITED TOXIN PRODUCTION. INCORPORATION OF (2-14)C-ACETATE INTO RUBRATOXIN WAS ENHANCED BY MALONATE AND FUMARATE + MALONATE. PYRUVATE + MALONATE PRODUCED A 40% INCREASE IN (2-14)C-ACETATE INCORPORATION INTO RUBRATOXIN. THE HIGHEST REDUCTION OF LABELED ACETATE INCORPORATION (36%) WAS CAUSED BY SUCCINATE OR ALPHA-KETOGLUTARATE COMBINED WITH MALONATE.、General Manufacturing Information: MAXIMUM MOLD GROWTH AND TOXIN PRODUCTION WAS FAVORED BY 20% GLUCOSE. THE HIGHEST YIELD OF RUBRATOXIN A APPEARED IN 6 DAYS. |
登记用途：Uses: Hepatotoxic metabolite from the molds Penicillium rubrum and P. purpurogenum、Often found growing in feedstuffs with Aspergillus sp.、May coexist with aflatoxins、[HSDB]、Rubratoxin A is a mycotoxin produced by fungi such as Penicillum rubrum and Penicillum purpurogenum、which are common soil fungi that sometimes contaminate animal feeds. (A2985、A2988)、Methods of Manufacturing: A STERILE GLUCOSE-MINERAL SALTS BROTH WAS INOCULATED WITH SPORE SUSPENSIONS OR MYCELIAL PELLETS OF PENICILLIUM RUBRUM AND INCUBATED QUIESCENTLY FOR 14 DAYS. RUBRATOXINS WERE RECOVERED FROM CULTURE FILTRATES BY ETHER EXTRACTION AND RESOLVED BY TLC. TOXIN FORMATION WAS ENHANCED BY MALONATE BUT WAS NOT MARKEDLY AFFECTED BY ETHYL MALONATE、SHIKIMATE、AND ACETATE OR BY ISOCITRATE OR OXALOACETATE ADDED IN THE PRESENCE OF MALONATE. CITRATE、CIS-ACONITATE、ALPHA-KETOGLUTARATE、SUCCINATE、FUMARATE AND MALONATE WHEN PRESENT IN THE MEDIUM ALONE OR IN CONJUNCTION WITH MALONATE CAUSED A 15-50% REDUCTION IN RUBRATOXIN FORMATION. ACETYL-COA (10-15 MOL、FLAS) CAUSED AN 80% INCREASE IN TOXIN YIELD. AT 10-3 MOLAR、CITRATE STIMULATED RUBRATOXIN A PRODUCTION BY AS MUCH AS 100%. ABOVE 10-3 MOLAR、CITRATE INHIBITED TOXIN PRODUCTION. INCORPORATION OF (2-14)C-ACETATE INTO RUBRATOXIN WAS ENHANCED BY MALONATE AND FUMARATE + MALONATE. PYRUVATE + MALONATE PRODUCED A 40% INCREASE IN (2-14)C-ACETATE INCORPORATION INTO RUBRATOXIN. THE HIGHEST REDUCTION OF LABELED ACETATE INCORPORATION (36%) WAS CAUSED BY SUCCINATE OR ALPHA-KETOGLUTARATE COMBINED WITH MALONATE.、General Manufacturing Information: MAXIMUM MOLD GROWTH AND TOXIN PRODUCTION WAS FAVORED BY 20% GLUCOSE. THE HIGHEST YIELD OF RUBRATOXIN A APPEARED IN 6 DAYS.。
化合物 Rubratoxin A 是一种化工化合物，登记 CAS 号为 22467-31-8，分子式 C26H32O11（分子量 520.5）。
登记 CAS 号：22467-31-8
其分子式 C26H32O11 由 26 个碳、32 个氢、11 个氧 组成。
别名/同义词：化合物 Rubratoxin A · RUBRATOXINA
化合物 Rubratoxin A 的 CAS 登记号为 22467-31-8。
分子式 C26H32O11，分子量 520.5。
别名/同义词：化合物 Rubratoxin A、RUBRATOXINA。
登记用途：Uses: Hepatotoxic metabolite from the molds Penicillium rubrum and P. purpurogenum、Often found growing in feedstuffs with Aspergillus sp.、May coexist with aflatoxins、[HSDB]、Rubratoxin A is a mycotoxin produced by fungi such as Penicillum rubrum and Penicillum purpurogenum、which are common soil fungi that sometimes contaminate animal feeds. (A2985、A2988)、Methods of Manufacturing: A STERILE GLUCOSE-MINERAL SALTS BROTH WAS INOCULATED WITH SPORE SUSPENSIONS OR MYCELIAL PELLETS OF PENICILLIUM RUBRUM AND INCUBATED QUIESCENTLY FOR 14 DAYS. RUBRATOXINS WERE RECOVERED FROM CULTURE FILTRATES BY ETHER EXTRACTION AND RESOLVED BY TLC. TOXIN FORMATION WAS ENHANCED BY MALONATE BUT WAS NOT MARKEDLY AFFECTED BY ETHYL MALONATE、SHIKIMATE、AND ACETATE OR BY ISOCITRATE OR OXALOACETATE ADDED IN THE PRESENCE OF MALONATE. CITRATE、CIS-ACONITATE、ALPHA-KETOGLUTARATE、SUCCINATE、FUMARATE AND MALONATE WHEN PRESENT IN THE MEDIUM ALONE OR IN CONJUNCTION WITH MALONATE CAUSED A 15-50% REDUCTION IN RUBRATOXIN FORMATION. ACETYL-COA (10-15 MOL、FLAS) CAUSED AN 80% INCREASE IN TOXIN YIELD. AT 10-3 MOLAR、CITRATE STIMULATED RUBRATOXIN A PRODUCTION BY AS MUCH AS 100%. ABOVE 10-3 MOLAR、CITRATE INHIBITED TOXIN PRODUCTION. INCORPORATION OF (2-14)C-ACETATE INTO RUBRATOXIN WAS ENHANCED BY MALONATE AND FUMARATE + MALONATE. PYRUVATE + MALONATE PRODUCED A 40% INCREASE IN (2-14)C-ACETATE INCORPORATION INTO RUBRATOXIN. THE HIGHEST REDUCTION OF LABELED ACETATE INCORPORATION (36%) WAS CAUSED BY SUCCINATE OR ALPHA-KETOGLUTARATE COMBINED WITH MALONATE.、General Manufacturing Information: MAXIMUM MOLD GROWTH AND TOXIN PRODUCTION WAS FAVORED BY 20% GLUCOSE. THE HIGHEST YIELD OF RUBRATOXIN A APPEARED IN 6 DAYS.。
化合物 Rubratoxin A（CAS 22467-31-8）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 22467-31-8 |
|---|---|
| PubChem CID | 56840856 |
| 分子式 | C26H32O11 |
| IUPAC 名称 | (3S)-3,13-dihydroxy-2-[(1S)-1-hydroxyheptyl]-10-[(S)-hydroxy-(6-oxo-2,3-dihydropyran-2-yl)methyl]-6,14-dioxatricyclo[10.3.0.04,8]pentadeca-1(12),4(8)-diene-5,7,15-trione |
| Molecular Weight | 520.5 |
|---|---|
| XLogP3 | 1.4 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 11 |
| Rotatable Bond Count | 8 |
| Exact Mass | 520.19446183 |
| Monoisotopic Mass | 520.19446183 |
| Topological Polar Surface Area | 177 |
| Heavy Atom Count | 37 |
| Melting Point | 210-214 °C (dec.) |
|---|
RUBRATOXIN A; 22467-31-8; BRN 1633008; HSDB 3532; DTXSID20176998; 5-19-08-00329 (Beilstein Handbook Reference); RefChem:180230; DTXCID6099489; RUBRATOXINA; HB4063
化合物 Rubratoxin A · CAS 22467-31-8 · C26H32O11. Melting Point: 210-214 °C (dec.).
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: RUBRATOXINA