Zafirlukast

Independent reference data for Zafirlukast (CAS 107753-78-6), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

For the prophylaxis and chronic treatment of asthma.Zafirlukast belongs to the leukotriene receptor antagonist (LTRA) class of medications and is available in strengths of 10 mg and 20 mg chewable tablets for oral administration. The U.S. Food and Drug Administration (FDA) approved the medication for managing chronic asthma in adults and children 5 or older. Zafirlukast is also used as an off-label drug to manage chronic urticaria, prevent exercise-induced bronchospasm, and treat allergic rhinitis in patients.

Synonyms and trade names

zafirlukast; 107753-78-6; Accolate; ICI-204219; ICI 204,219; ICI 204219; DTXSID5023746; Cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate; XZ629S5L50; ICI-204,219; 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide; DTXCID303746; CHEBI:10100; cyclopentyl 3-[2-methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl]-1-methylindole-5-carbamate; zafirlukastum; 4-(5-cyclopentyloxycarbonylamino-2-methylindol-3-yl-methyl)-3-methoxy-N-O-tolylsulfonylbenzamide

GHS hazard classification

Reported hazard statements	H413 (92.9%)

H413 (92.9%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]

P273, and P501 (click each P-code to see the statement)

What the public record says

Zafirlukast · CAS 107753-78-6 · C31H33N3O6S. UNII XZ629S5L50. Melting Point: 139; Melting Point: 139 °C; Solubility: 9.62e-04 g/L.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.