伐普肽

Description

Vapreotide · CAS 103222-11-3 · C57H70N12O9S2. UNII 2PK59M9GFF.

Identification

CAS Registry Number	103222-11-3
PubChem CID	6918026
Molecular formula	C57H70N12O9S2
IUPAC name	(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
UNII (FDA)	2PK59M9GFF

Computed Descriptors

Molecular Weight	1131.4
XLogP3	3.6
Hydrogen Bond Donor Count	13
Hydrogen Bond Acceptor Count	13
Rotatable Bond Count	18
Exact Mass	1130.48301420
Monoisotopic Mass	1130.48301420
Topological Polar Surface Area	401
Heavy Atom Count	80
Formal Charge	0

Physical description & handling notes

• Vapreotide is a somatostatin analog with a higher metabolic stability than the parent hormone. Vapreotide reduces splanchnic blood flow; inhibits growth hormone release, and inhibits the release of peptides and vasoactive compounds from neuroendocrine tumors.

Documented Uses

• For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.
• Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
• Substances that inhibit or prevent the proliferation of NEOPLASMS.
• H - Systemic hormonal preparations, excl. sex hormones and insulins
• H01 - Pituitary and hypothalamic hormones and analogues
• H01CB - Somatostatin and analogues

Synonyms

Vapreotide; 103222-11-3; Vapreotida; Vapreotidum; Sanvar IR; 2PK59M9GFF; BMY-41606; CCRIS 6495; RC-160; DTXSID00883113; BMY 41606; D-phenylalanyl-cysteinyl-tyrosyl-D-tryptophyl-lysyl-valyl-cysteinyl-tryptophanamide; RefChem:193718; H01CB04; DTXCID201022687; D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH2

Frequently Asked Questions

What are the CAS number and molecular formula of Vapreotide?

CAS 103222-11-3; molecular formula C57H70N12O9S2; molecular weight — g/mol.

What other names is Vapreotide known by?

Vapreotide, 103222-11-3, Vapreotida, Vapreotidum, Sanvar IR, 2PK59M9GFF.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.