Troglitazone

Independent reference data for Troglitazone (CAS 97322-87-7), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.Troglitazone was the first thiazolidinedione approved for use in the United States and was licensed for use in type 2 diabetes in 1997, but withdrawn 3 years later because of the frequency of liver injury including acute liver failure associated with its use.

Synonyms and trade names

troglitazone; 97322-87-7; Rezulin; Romglizone; Prelay; CS-045; Romozin; Noscal; troglitazona; troglitazonum; CI-991; DTXSID8023719; GR92132X; GR-92132X; 5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione; CHEBI:9753

What the public record says

Troglitazone · CAS 97322-87-7 · C24H27NO5S. UNII I66ZZ0ZN0E. Melting Point: 184-186 °C; LogP: 3.6; LogP: 2.7.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.