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Troglitazone

CAS 97322-87-7C24H27NO5SMW 441.5

Troglitazone (CAS 97322-87-7) — formula C24H27NO5S, molecular weight 441.5; category organic chemicals.

Product Description

Troglitazone (CAS 97322-87-7) is a chemical raw material in the organic chemicals category. Its molecular formula C24H27NO5S comprises 24 C, 27 H, 1 N, 5 O, 1 S atoms. Its molecular weight is about 441.5. Reported physicochemical data: melting point around 184-186 °C, LogP about 3.6. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number97322-87-7
Molecular FormulaC24H27NO5S
Molecular Weight441.5
Melting Point184-186 °C
LogP3.6
ApplicationsFor the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise
CategoryOrganic Chemicals

Applications

Documented applications: For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.

Technical Profile

What this product is

Troglitazone is a carbon-based organic compound with CAS registry number 97322-87-7 and molecular formula C24H27NO5S (molecular weight 441.5), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 97322-87-7

Its molecular formula C24H27NO5S comprises 24 C, 27 H, 1 N, 5 O, 1 S atoms.

Also known as: Troglitazone · 曲格列酮

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of Troglitazone?

The CAS registry number of Troglitazone is 97322-87-7.

What is the molecular formula and molecular weight of Troglitazone?

Molecular formula C24H27NO5S, molecular weight 441.5.

What other names is Troglitazone known by?

It is also registered under: Troglitazone, 曲格列酮.

What are the documented applications of Troglitazone?

Recorded applications: For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.

Which category does Troglitazone belong to?

Category: Organic Chemicals.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Troglitazone (CAS 97322-87-7), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number97322-87-7
PubChem CID5591
Molecular formulaC24H27NO5S
IUPAC name5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
UNII (FDA)I66ZZ0ZN0E

Computed descriptors

Molecular Weight441.5
XLogP35.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass441.16099414
Monoisotopic Mass441.16099414
Topological Polar Surface Area110
Heavy Atom Count31

Physicochemical values on record

Melting Point184-186 °C
LogP3.6
LogP2.7

Documented uses on record

    For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.Troglitazone was the first thiazolidinedione approved for use in the United States and was licensed for use in type 2 diabetes in 1997, but withdrawn 3 years later because of the frequency of liver injury including acute liver failure associated with its use.

    Synonyms and trade names

    troglitazone; 97322-87-7; Rezulin; Romglizone; Prelay; CS-045; Romozin; Noscal; troglitazona; troglitazonum; CI-991; DTXSID8023719; GR92132X; GR-92132X; 5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione; CHEBI:9753

    What the public record says

    Troglitazone · CAS 97322-87-7 · C24H27NO5S. UNII I66ZZ0ZN0E. Melting Point: 184-186 °C; LogP: 3.6; LogP: 2.7.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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中文页面: 曲格列酮

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