trimipramine maleate

Independent reference data for trimipramine maleate (CAS 521-78-8), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Documented uses on record

For the treatment of depression and depression accompanied by anxiety, agitation or sleep disturbanceSubstances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.

Synonyms and trade names

Trimipramine maleate; 521-78-8; Trimipramine hydrogen maleate; Stangyl; DTXSID2045315; NSC-758386; 269K6498LD; 5-(3-(Dimethylamino)-2-methylpropyl)-10,11-dihydro-5H-dibenz(b,f)azepine maleate (1:1); DTXCID0025315; Rhotrimine; 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (Z)-2-butenedioate (1:1); CHEBI:35030; 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (2Z)-2-butenedioate (1:1); Trimipramine Maleate (1:1); RefChem:56472; 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)-2-methylpropyl)-, Maleate(1:1)

GHS hazard classification

Reported hazard statements	H302 (100%), H315 (76.9%), H319 (76.9%), H335 (76.9%), H361 (78.8%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (76.9%): Causes skin irritation [Warning Skin corrosion/irritation]

What the public record says

trimipramine maleate · CAS 521-78-8 · C24H30N2O4. UNII 269K6498LD.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.