Trichostatin A

Independent reference data for Trichostatin A (CAS 58880-19-6), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Documented uses on record

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.

Synonyms and trade names

trichostatin A; 58880-19-6; DTXSID6037063; CHEBI:46024; 3X2S926L3Z; 2,4-Heptadienamide, 7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-; 7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide; VTR297; VTR-297; (2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide; NSC-311042; TSA antibioitc; 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE; NSC311042; RefChem:899268; DTXCID4017063

GHS hazard classification

Reported hazard statements	H302, H312, H332 (15%), H315 (98.9%), H317 (98.4%), H319 (99.5%), H335 (98.4%)

H302+H312+H332 (15%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]

H302 (99.5%): Harmful if swallowed [Warning Acute toxicity, oral]

What the public record says

Trichostatin A · CAS 58880-19-6 · C17H22N2O3. UNII 3X2S926L3Z.

Source: PubChem / Wikidata; the batch COA governs where values differ.