tranylcypromine (CAS 155-09-9) — formula C9H11N, molecular weight 133.19; category organic chemicals.
| CAS Number | 155-09-9 |
|---|---|
| Molecular Formula | C9H11N |
| Molecular Weight | 133.19 |
| Melting Point | 79-80 °C at 1.50E+00 mm Hg |
| Boiling Point | 79-80 °C @ 1.5-1.6 mm Hg |
| LogP | 1.58 |
| Applications | Uses: MEDICATION, Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 75.3, Primarily indicated for the treatment of clinical depression. It is generally used to remedy various types of mood and anxiety disorders, typically after a last resort only after conventional antidepressants have been tried without success. It also has some off-label uses, such as in the treatment of post-traumatic stress disorder (PTSD). [Wikipedia], Methods of Manufacturing: Burger, Yost, J Amer Chem Soc 70, 2198 (1948), Tedeschi, US patent 2, 997, 422 (1961 to SK & F)., Formulations, Preparations: Parnate, Tylciprine, Sulfate, DOSAGE FORMS--TABLETS NF: 10 MG., SULFATE, General Manufacturing Information: TRANYLCYPROMINE WAS WITHDRAWN FROM MARKET FOR SOME MONTHS DURING 1964, BUT AGAIN BECAME AVAIL FOR USE IN PT UNDER CLOSE MEDICAL OBSERVATION. |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION, Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 75.3, Primarily indicated for the treatment of clinical depression. It is generally used to remedy various types of mood and anxiety disorders, typically after a last resort only after conventional antidepressants have been tried without success. It also has some off-label uses, such as in the treatment of post-traumatic stress disorder (PTSD). [Wikipedia], Methods of Manufacturing: Burger, Yost, J Amer Chem Soc 70, 2198 (1948), Tedeschi, US patent 2, 997, 422 (1961 to SK & F)., Formulations, Preparations: Parnate, Tylciprine, Sulfate, DOSAGE FORMS--TABLETS NF: 10 MG., SULFATE, General Manufacturing Information: TRANYLCYPROMINE WAS WITHDRAWN FROM MARKET FOR SOME MONTHS DURING 1964, BUT AGAIN BECAME AVAIL FOR USE IN PT UNDER CLOSE MEDICAL OBSERVATION..
tranylcypromine is a carbon-based organic compound with CAS registry number 155-09-9 and molecular formula C9H11N (molecular weight 133.19), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 155-09-9
Its molecular formula C9H11N comprises 9 C, 11 H, 1 N atoms.
Also known as: tranylcypromine · 反苯环丙明
Category: organic chemicals
The CAS registry number of tranylcypromine is 155-09-9.
Molecular formula C9H11N, molecular weight 133.19.
It is also registered under: tranylcypromine, 反苯环丙明.
Recorded applications: Uses: MEDICATION, Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 75.3, Primarily indicated for the treatment of clinical depression. It is generally used to remedy various types of mood and anxiety disorders, typically after a last resort only after conventional antidepressants have been tried without success. It also has some off-label uses, such as in the treatment of post-traumatic stress disorder (PTSD). [Wikipedia], Methods of Manufacturing: Burger, Yost, J Amer Chem Soc 70, 2198 (1948), Tedeschi, US patent 2, 997, 422 (1961 to SK & F)., Formulations, Preparations: Parnate, Tylciprine, Sulfate, DOSAGE FORMS--TABLETS NF: 10 MG., SULFATE, General Manufacturing Information: TRANYLCYPROMINE WAS WITHDRAWN FROM MARKET FOR SOME MONTHS DURING 1964, BUT AGAIN BECAME AVAIL FOR USE IN PT UNDER CLOSE MEDICAL OBSERVATION..
Category: Organic Chemicals.
Independent reference data for tranylcypromine (CAS 155-09-9), compiled from public chemistry databases.
| CAS Registry Number | 155-09-9 |
|---|---|
| PubChem CID | 5530 |
| Molecular formula | C9H11N |
| IUPAC name | 2-phenylcyclopropan-1-amine |
| UNII (FDA) | 3E3V44J4Z9 |
| Molecular Weight | 133.19 |
|---|---|
| XLogP3 | 1.5 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 1 |
| Exact Mass | 133.089149355 |
| Monoisotopic Mass | 133.089149355 |
| Topological Polar Surface Area | 26 |
| Heavy Atom Count | 10 |
| Boiling Point | 79-80 °C @ 1.5-1.6 mm Hg |
|---|---|
| Melting Point | 79-80 °C at 1.50E+00 mm Hg |
| Melting Point | MP: 164-166 °C /Hydrochloride/ |
| Solubility | 48600 |
| LogP | 1.58 |
| LogP | log Kow= 1.58 @ 25 °C |
| LogP | 1.49 |
tranylcypromine; dl-Tranylcypromine; Transamine; Racemic Tranylcypromine; Jatrosom; Parnitene; SKF 385; Tranilcipromina; Tranylcyprominum; NSC80664; NSC-80664; Cyclopropanamine, 2-phenyl-, trans-(+-)-; Cyclopropylamine, 2-phenyl-, trans-(+-)-; DTXSID2023694; Tranylcypromin; trans 2 Phenylcyclopropylamine
| Reported hazard statements | H302 (100%), H315 (100%), H319 (100%) |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
tranylcypromine · CAS 155-09-9 · C9H11N. UNII 3E3V44J4Z9. Boiling Point: 79-80 °C @ 1.5-1.6 mm Hg; Melting Point: 79-80 °C at 1.50E+00 mm Hg; Melting Point: MP: 164-166 °C /Hydrochloride/.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 反苯环丙明