Toremifene

Independent reference data for Toremifene (CAS 89778-26-7), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

For the treatment of metastatic breast cancer in postmenopausal women with estrogen receptor-positive or receptor-unknown tumors. Toremifene is currently under investigation as a preventative agent for prostate cancer in men with high-grade prostatic intraepithelial neoplasia and no evidence of prostate cancer.Toremifene is a nonsteroidal antiestrogen that is used in the treatment of estrogen receptor positive breast cancer. Long term toremifene therapy has been associated with development of fatty liver, steatohepatitis, cirrhosis, and rare instances of clinically apparent acute liver injury.

Synonyms and trade names

toremifene; 89778-26-7; Acapodene; Farestone; Toremifeno; Toremifenum; Chlortamoxifen; Toremiphene; GTx-006; 7NFE54O27T; J33.157K; (Z)-2-(4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine; CHEBI:9635; DTXSID3023689; (2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine; Ethanamine, 2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-

What the public record says

Toremifene · CAS 89778-26-7 · C26H28ClNO. UNII 7NFE54O27T. Melting Point: 108-110 °C; Melting Point: 108 - 110 °C; Solubility: 4.09e-04 g/L.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.