Torasemide

Description

Torasemide · CAS 56211-40-6 · C16H20N4O3S. UNII W31X2H97FB. Melting Point: 163-164 °C; Melting Point: 164 - 164 °C; Solubility: 5.96e-02 g/L.

Identification

CAS Registry Number	56211-40-6
PubChem CID	41781
Molecular formula	C16H20N4O3S
IUPAC name	1-[[4-(3-methylanilino)-3-pyridinyl]sulfonyl]-3-propan-2-ylurea
UNII (FDA)	W31X2H97FB

Computed Descriptors

Molecular Weight	348.4
XLogP3	2.7
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	348.12561169
Monoisotopic Mass	348.12561169
Topological Polar Surface Area	109
Heavy Atom Count	24
Formal Charge	0

Physical & Chemical Properties

Melting Point	163-164 °C
Melting Point	164 - 164 °C
Solubility	5.96e-02 g/L
LogP	3.356
LogP	2.3
LogP	1.21
Dissociation Constants	7.1

Physical description & handling notes

• Solid
• Soluble
• >52.3 [ug/mL] (The mean of the results at pH 7.4)

Regulatory Status

GHS notification summary	2.8% (3 / 109)

GHS Hazard Classification

GHS notification summary	2.8% (3 / 109)
Reported hazard statements	H319 (86.2%), H361 (12.8%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >10000
• Use (kg; exact) in Germany (2009): 10366
• Consumption (g per capita; approx.) in Germany (2009): 0.122
• Consumption (g per capita; exact) in Germany (2009): 0.127
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Torasemide is indicated for the treatment of edema associated with congestive heart failure, renal or hepatic diseases. From this condition, it has been observed that torasemide is very effective in cases of kidney failure. As well, torasemide is approved to be used as an antihypertensive agent either alone or in combination with other antihypertensives.

Synonyms

Torasemide; TORSEMIDE; 56211-40-6; Luprac; Torasemida; Torasemidum; BM-02015; AC-4464; Soaanz; Upcard; JDL 464; AC4464; DTXSID2023690; AC 4464; Torasemide anhydrous; 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea

Frequently Asked Questions

What are the CAS number and molecular formula of Torasemide?

CAS 56211-40-6; molecular formula C16H20N4O3S; molecular weight — g/mol.

What other names is Torasemide known by?

Torasemide, TORSEMIDE, 56211-40-6, Luprac, Torasemida, Torasemidum.

Is Torasemide classified as hazardous?

2.8% of GHS notifications report no hazard classification (3 of 109).

What are the key physical properties of Torasemide?

Melting Point: 163-164 °C; Melting Point: 164 - 164 °C; Solubility: 5.96e-02 g/L; LogP: 3.356.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.