Tolbutamide (CAS 64-77-7) — formula C12H18N2O3S, molecular weight 270.35; category organic chemicals.
Tolbutamide (CAS 64-77-7) is a chemical raw material in the organic chemicals category. Its molecular formula C12H18N2O3S comprises 12 C, 18 H, 2 N, 3 O, 1 S atoms. Its molecular weight is about 270.35. Reported physicochemical data: melting point around 262 to 264 °F (NTP, 1992), LogP about 2.34. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 64-77-7 |
|---|---|
| Molecular Formula | C12H18N2O3S |
| Molecular Weight | 270.35 |
| Melting Point | 262 to 264 °F (NTP, 1992) |
| LogP | 2.34 |
| Applications | Therap cat: Antidiabetic, Therap cat (Vet): Hypoglycemic agent, An orally effective hypoglycemic drug, Methods of Manufacturing: FROM BUTYL ISOCYANATE & 4-TOLUENESULFONAMIDE SODIUM, British patent 808, 071 and Aumuller |
| Category | Organic Chemicals |
Documented applications: Therap cat: Antidiabetic, Therap cat (Vet): Hypoglycemic agent, An orally effective hypoglycemic drug, Methods of Manufacturing: FROM BUTYL ISOCYANATE & 4-TOLUENESULFONAMIDE SODIUM, British patent 808, 071 and Aumuller.
Tolbutamide is a carbon-based organic compound with CAS registry number 64-77-7 and molecular formula C12H18N2O3S (molecular weight 270.35), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 64-77-7
Its molecular formula C12H18N2O3S comprises 12 C, 18 H, 2 N, 3 O, 1 S atoms.
Also known as: Tolbutamide · 甲苯磺丁脲
Category: organic chemicals
The CAS registry number of Tolbutamide is 64-77-7.
Molecular formula C12H18N2O3S, molecular weight 270.35.
It is also registered under: Tolbutamide, 甲苯磺丁脲.
Recorded applications: Therap cat: Antidiabetic, Therap cat (Vet): Hypoglycemic agent, An orally effective hypoglycemic drug, Methods of Manufacturing: FROM BUTYL ISOCYANATE & 4-TOLUENESULFONAMIDE SODIUM, British patent 808, 071 and Aumuller.
Category: Organic Chemicals.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Tolbutamide (CAS 64-77-7), compiled from public chemistry databases.
| CAS Registry Number | 64-77-7 |
|---|---|
| PubChem CID | 5505 |
| Molecular formula | C12H18N2O3S |
| IUPAC name | 1-butyl-3-(4-methylphenyl)sulfonylurea |
| UNII (FDA) | 982XCM1FOI |
| Molecular Weight | 270.35 |
|---|---|
| XLogP3 | 2.3 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 5 |
| Exact Mass | 270.10381361 |
| Monoisotopic Mass | 270.10381361 |
| Topological Polar Surface Area | 83.7 |
| Heavy Atom Count | 18 |
| Melting Point | 262 to 264 °F (NTP, 1992) |
|---|---|
| Melting Point | 128.5 |
| Melting Point | 128.5-129.5 °C |
| Melting Point | 128.5 °C |
| Solubility | 109 |
| Solubility | In water, 109 mg/l @ 37 °C |
| Solubility | 2.02e-01 g/L |
| Density | 1.245 g/cu cm @ 25 °C |
| LogP | 2.34 |
| LogP | log Kow= 2.34 |
tolbutamide; 64-77-7; Diabetamid; Arkozal; Butamide; Willbutamide; Artosin; Ipoglicone; Rastinon; 1-Butyl-3-(p-tolylsulfonyl)urea; 1-Butyl-3-tosylurea; Diabetol; Diabuton; Glyconon; Tolbutamid; Aglicid
| Reported hazard statements | H302 (28.6%), H317 (57.1%), H361 (14.3%), H370 (14.3%) |
|---|
H302 (28.6%): Harmful if swallowed [Warning Acute toxicity, oral]
H317 (57.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]
Tolbutamide · CAS 64-77-7 · C12H18N2O3S. UNII 982XCM1FOI. Melting Point: 262 to 264 °F (NTP, 1992); Melting Point: 128.5; Melting Point: 128.5-129.5 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 甲苯磺丁脲