替比法尼

Name: 替比法尼
Brand: 济南圣和化工有限公司

CAS 192185-72-1C27H22Cl2N4OMW 489.4

替比法尼（CAS 192185-72-1）属有机化学品类产品，分子式 C27H22Cl2N4O，分子量 489.4。济南圣和化工有限公司常年现货供应该产品，常规纯度按批次COA提供(不公开发布)，可按客户需求安排分装包装，欢迎邮件或来电询价。

产品概览

CAS号	192185-72-1
分子式	C27H22Cl2N4O
分子量	489.4
LogP	4.1
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	有机化学品
类别	有机化学品

应用领域

有机化学品

替比法尼主要应用于有机化学品。具体使用工况下的添加量与规格要求，欢迎与技术团队沟通确认。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供货能力：替比法尼备有现货，包装形式为按订单/批次确认(不公开发布)。我们支持对公转账并开具增值税发票，山东省内可安排快速配送，省外按物流时效发货，具体请联系 info@591daili.com。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择济南圣和化工有限公司的理由：产品信息透明（含 CAS、分子式、理化参数）、报价响应快（一个工作日内）、单证齐全（COA/MSS/质检资料按需提供）、支持批量与长期协议供货。如需替比法尼以外的配套原料，也欢迎一并列出需求清单。

常见问题

替比法尼的 CAS 号是多少？

替比法尼的 CAS 号为 192185-72-1。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

替比法尼有什么用途？

主要应用于有机化学品。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Tipifarnib · CAS 192185-72-1 · C27H22Cl2N4O. UNII MAT637500A.

Identification

CAS Registry Number	192185-72-1
PubChem CID	159324
Molecular formula	C27H22Cl2N4O
IUPAC name	6-[(R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2-one
UNII (FDA)	MAT637500A

Computed Descriptors

Molecular Weight	489.4
XLogP3	4.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	488.1170667
Monoisotopic Mass	488.1170667
Topological Polar Surface Area	64.2
Heavy Atom Count	34
Formal Charge	0

Physical description & handling notes

R115777, a nonpeptidomimetic farnesyl transferase inhibitor, suppresses the growth of human pancreatic adenocarcinoma cell lines. This growth inhibition is associated with modulation in the phosphorylation levels of signal transducers and activators of transcription 3 (STAT3) and extracellular signal-regulated kinases (ERK).

GHS Hazard Classification

Reported hazard statements	H302 (33.3%), H315 (100%), H319 (100%), H335 (66.7%), H373 (33.3%)

H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

Investigated for use/treatment in colorectal cancer, leukemia (myeloid), pancreatic cancer, and solid tumors.
Substances that inhibit or prevent the proliferation of NEOPLASMS.

Synonyms

Tipifarnib; 192185-72-1; Zarnestra; R-115777; (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone; tipifarnibum; R-11577; NSC-702818; 6-[(R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2-one; MAT637500A; DTXSID5041140; CHEBI:141969; NSC702818; (R)-6-[Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone; 6-((R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2-one; RefChem:898221

Frequently Asked Questions

What are the CAS number and molecular formula of Tipifarnib?

CAS 192185-72-1; molecular formula C27H22Cl2N4O; molecular weight — g/mol.

What other names is Tipifarnib known by?

Tipifarnib, 192185-72-1, Zarnestra, R-115777, (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone, tipifarnibum.

Is Tipifarnib classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H373.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.