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Tipifarnib

CAS 192185-72-1C27H22Cl2N4OMW 489.4

Tipifarnib (CAS No. 192185-72-1) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of per batch COA (not published). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Product Overview

CAS Number192185-72-1
Molecular FormulaC27H22Cl2N4O
Molecular Weight489.4
LogP4.1
Purityper batch COA (not published)
Packagingper order / batch confirmation (not published)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Applications

Organic Chemicals

Packaging & Storage

Packagingper order / batch confirmation (not published)
Purityper batch COA (not published)
StorageSealed, cool and dry place
ShippingStandard chemical transport
SampleAvailable on request
Lead TimeIn stock / per order

Quality & Documentation

COA (Certificate of Analysis) is provided with every batch. MSDS/technical data sheets and third-party test reports are available on request. Purity and packaging are subject to batch COA and order confirmation.

Product Profile

Product Overview

Tipifarnib is a carbon-based organic compound with CAS registry number 192185-72-1 and molecular formula C27H22Cl2N4O (molecular weight 489.4), belonging to the organic chemicals segment of chemical raw materials.

Organic chemicals are the largest family of carbon-based compounds, widely used across pharmaceuticals, agrochemicals, materials, cosmetics and food industries.

Jinan Shenghe Chemical Co., Ltd. supplies Tipifarnib with stable inventory and provides a Certificate of Analysis (COA) with each batch; custom repacking is available per process requirement.

Chemical Identity & Nomenclature

CAS number: 192185-72-1 — searchable in PubChem for physicochemical, safety and regulatory data.

Its molecular formula C27H22Cl2N4O comprises 27 C, 22 H, 2 Cl, 4 N, 1 O atoms.

Also known as: Tipifarnib

Category: organic chemicals

Applications & Use Cases

Downstream uses span pharmaceutical ingredients, agrochemicals, dyes, solvents, surfactants, food additives and polymer materials.

Specifications & Quality

Typical purity is per batch COA (not published). Packaging is per order / batch confirmation (not published). Storage: sealed, in a cool and dry place. Each batch ships with a COA; MSDS and other technical documents are available on request.

Sourcing & Support

Supplier: Jinan Shenghe Chemical Co., Ltd.. Samples can be arranged on request; lead time depends on stock and order size. Quotes are returned within one business day by email or WhatsApp.

Email: info@591daili.com · Tel/WhatsApp: +86-18553102138

Frequently Asked Questions

What is the CAS number of Tipifarnib?

The CAS number of Tipifarnib is 192185-72-1.

What purity and packaging are available?

Typical purity is per batch COA (not published), supplied in per order / batch confirmation (not published), with COA provided.

What are the applications of Tipifarnib?

Main applications include Organic Chemicals.

What quality documents are provided?

Each batch ships with a Certificate of Analysis (COA). MSDS and other technical documents are available on request.

How should Tipifarnib be stored and handled?

Store sealed in a cool, dry place. Handling and PPE follow the MSDS supplied with the batch; general chemical-handling precautions are recommended.

Can I request a sample?

Samples are available on request. Please contact us at info@591daili.com or via WhatsApp for details.

How do I buy Tipifarnib or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Tipifarnib · CAS 192185-72-1 · C27H22Cl2N4O. UNII MAT637500A.

Identification

CAS Registry Number192185-72-1
PubChem CID159324
Molecular formulaC27H22Cl2N4O
IUPAC name6-[(R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2-one
UNII (FDA)MAT637500A

Computed Descriptors

Molecular Weight489.4
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass488.1170667
Monoisotopic Mass488.1170667
Topological Polar Surface Area64.2
Heavy Atom Count34
Formal Charge0

Physical description & handling notes

  • R115777, a nonpeptidomimetic farnesyl transferase inhibitor, suppresses the growth of human pancreatic adenocarcinoma cell lines. This growth inhibition is associated with modulation in the phosphorylation levels of signal transducers and activators of transcription 3 (STAT3) and extracellular signal-regulated kinases (ERK).

GHS Hazard Classification

Reported hazard statementsH302 (33.3%), H315 (100%), H319 (100%), H335 (66.7%), H373 (33.3%)

H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

  • Investigated for use/treatment in colorectal cancer, leukemia (myeloid), pancreatic cancer, and solid tumors.
  • Substances that inhibit or prevent the proliferation of NEOPLASMS.

Synonyms

Tipifarnib; 192185-72-1; Zarnestra; R-115777; (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone; tipifarnibum; R-11577; NSC-702818; 6-[(R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2-one; MAT637500A; DTXSID5041140; CHEBI:141969; NSC702818; (R)-6-[Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone; 6-((R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2-one; RefChem:898221

Frequently Asked Questions

What are the CAS number and molecular formula of Tipifarnib?

CAS 192185-72-1; molecular formula C27H22Cl2N4O; molecular weight — g/mol.

What other names is Tipifarnib known by?

Tipifarnib, 192185-72-1, Zarnestra, R-115777, (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone, tipifarnibum.

Is Tipifarnib classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H373.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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