THPS

Description

Tetrakis Hydroxymethyl Phosphonium Sulfate · CAS 55566-30-8 · C8H24O12P2S. UNII 5I8RSL9E6S. Boiling Point: 232 °F at 760 mmHg (NTP, 1992); Melting Point: -31 °F (NTP, 1992).

Identification

CAS Registry Number	55566-30-8
PubChem CID	41478
Molecular formula	C8H24O12P2S
IUPAC name	bis(tetrakis(hydroxymethyl)phosphanium);sulfate
UNII (FDA)	5I8RSL9E6S

Computed Descriptors

Molecular Weight	406.28
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	8
Exact Mass	406.04637137
Monoisotopic Mass	406.04637137
Topological Polar Surface Area	250
Heavy Atom Count	23
Formal Charge	0
Complexity	118

Physical & Chemical Properties

Boiling Point	232 °F at 760 mmHg (NTP, 1992)
Melting Point	-31 °F (NTP, 1992)

Physical description & handling notes

• Tetrakis(hydroxymethyl)phosphonium sulfate solution is a clear colorless viscous liquid. (NTP, 1992)
• CBI; Liquid
• Crystalline solid; [ACGIH] Available commercially as an aqueous solution; [MSDSonline]
• Crystalline solid
• greater than 200 °F (NTP, 1992)
• greater than or equal to 100 mg/mL at 64 °F (NTP, 1992)

Regulatory Status

Regulatory & Food Contact

FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS FDA Inventory of Effective Food Contact Substance (FCS) Noti: FCS Tetrakis (hydroxymethyl) phosphonium sulfate (THPS) (CAS Reg. No. 55566-30-8) As a preservative in coatings intended for use on paper and paperboard that may contact food. The FCS may be used at levels not to exceed 400 ppm in water-based coatings, starches, pigments, and filler sl

GHS notification summary

0.4% (2 / 472)

GHS Hazard Classification

GHS notification summary	0.4% (2 / 472)
Reported hazard statements	H301 (30.1%), H302 (66.1%), H317 (99.6%), H318 (99.6%), H330 (30.1%), H331 (46.8%), H360 (16.7%), H361 (35.8%)

Documented Uses

• Used to make crease-resistant and flame-retardant finishes for textiles, e.g., children's sleepwear; [ACGIH] Also used as a biocide; [HSDB]
• Using Disinfectants or Biocides [Category: Clean]
• Textiles (Printing, Dyeing, or Finishing) [Category: Industry]
• Both oil base and water base fracturing fluids are being used in the fracturing industry. Water base, which includes alcohol-water mixtures and low strength acids, make up the majority of treating fluids. The common chemicals added to these fluids are polymers for viscosity development, crosslinkers for viscosity enhancement, pH control chemicals, gel breakers for polymer degradation following the treatment, surfactants, clay stabilizers, alcohol, bactericides, fluid loss additives and friction reducer. /Hydraulic
• Hydraulic fracturing uses a specially blended liquid which is pumped into a well under extreme pressure causing cracks in rock formations underground. These cracks in the rock then allow oil and natural gas to flow, increasing resource production. ... Chemical Name: Tetrakis hydroxymethyl-phosphonium sulfate; Chemical Purpose: Eliminates bacteria in the water that produces corrosive by-products; Product Function: Biocide.
• For more Uses (Complete) data for TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE (8 total), please visit the HSDB record page.

Synonyms

TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE; 55566-30-8; Retardol S; Pyroset TKO; CCRIS 316; DTXSID0021331; HSDB 4215; Octakis(hydroxymethyl)phosphonium sulfate; NCI-C55050; UNII-5I8RSL9E6S; EINECS 259-709-0; 5I8RSL9E6S; Bis(tetrakis(hydroxymethyl)phosphonium)sulfate (salt); bis[tetrakis(hydroxymethyl)phosphonium] sulfate; Phosphonium, tetrakis(hydroxymethyl)-, sulfate (2:1) (salt); Phosphonium, tetrakis(hydroxymethyl)-, sulfate (2:1)

Frequently Asked Questions

What are the CAS number and molecular formula of Tetrakis Hydroxymethyl Phosphonium Sulfate?

CAS 55566-30-8; molecular formula C8H24O12P2S; molecular weight — g/mol.

What other names is Tetrakis Hydroxymethyl Phosphonium Sulfate known by?

TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE, 55566-30-8, Retardol S, Pyroset TKO, CCRIS 316, DTXSID0021331.

What is the regulatory status of Tetrakis Hydroxymethyl Phosphonium Sulfate?

Documented regulatory listings: FDA Cumulative Estimated Daily Intake (CEDI): FCS; FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS; FDA Inventory of Effective Food Contact Substance (FCS) Noti: FCS.

Is Tetrakis Hydroxymethyl Phosphonium Sulfate classified as hazardous?

0.4% of GHS notifications report no hazard classification (2 of 472).

What are the key physical properties of Tetrakis Hydroxymethyl Phosphonium Sulfate?

Boiling Point: 232 °F at 760 mmHg (NTP, 1992); Melting Point: -31 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.