Theophylline

Independent reference data for Theophylline (CAS 58-55-9), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

Theophylline is an old drug experiencing a renaissance owing to its beneficial antiinflammatory effects in chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease. Multiple modes of antiinflammatory action have been reported, including inhibition of the enzymes that degrade cAMP-phosphodiesterase (PDE).Bronchodilator Agents; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Vasodilator Agents

Synonyms and trade names

theophylline; 58-55-9; 1,3-Dimethylxanthine; Elixophyllin; Theophyllin; Theolair; Nuelin; Theophylline anhydrous; Elixophylline; Lanophyllin; Pseudotheophylline; Respbid; Solosin; Theocin; Theo-dur; Liquophylline

Regulatory listings held on file

Regulatory & Food Contact	CIR / INCI: Cosmetic ingredients (Theophylline) -> CIR (Cosmetic Ingredient Review)
GHS notification summary	0.3% (1 / 308)

GHS hazard classification

GHS notification summary	0.3% (1 / 308)
Reported hazard statements	H301 (88%), H302 (11.7%), H360, H402, H361, H362, H370, H372

H360D: May damage the unborn child [Danger Reproductive toxicity]

P203, P280, P318, P405, and P501 (click each P-code to see the statement)

What the public record says

Theophylline · CAS 58-55-9 · C7H8N4O2. UNII 0I55128JYK. Melting Point: 522 to 525 °F (NTP, 1992); Melting Point: 273; Melting Point: 274 °C.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.