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thalidomide

CAS 50-35-1C13H10N2O4MW 258.23

thalidomide (CAS 50-35-1) — formula C13H10N2O4, molecular weight 258.23; category organic chemicals.

Product Description

thalidomide (CAS 50-35-1) is a chemical raw material in the organic chemicals category. Its molecular formula C13H10N2O4 comprises 13 C, 10 H, 2 N, 4 O atoms. Its molecular weight is about 258.23. Reported physicochemical data: melting point around 516 to 520 °F (NTP, 1992), LogP about 0.33. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number50-35-1
Molecular FormulaC13H10N2O4
Molecular Weight258.23
Melting Point516 to 520 °F (NTP, 1992)
LogP0.33
ApplicationsMEDICATION, Angiogenesis Inhibitors, Immunosuppressive Agents, Leprostatic Agents, Teratogens, For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma
CategoryOrganic Chemicals

Applications

Documented applications: MEDICATION, Angiogenesis Inhibitors, Immunosuppressive Agents, Leprostatic Agents, Teratogens, For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma.

Technical Profile

What this product is

thalidomide is a carbon-based organic compound with CAS registry number 50-35-1 and molecular formula C13H10N2O4 (molecular weight 258.23), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 50-35-1

Its molecular formula C13H10N2O4 comprises 13 C, 10 H, 2 N, 4 O atoms.

Also known as: thalidomide · 沙利度胺

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of thalidomide?

The CAS registry number of thalidomide is 50-35-1.

What is the molecular formula and molecular weight of thalidomide?

Molecular formula C13H10N2O4, molecular weight 258.23.

What other names is thalidomide known by?

It is also registered under: thalidomide, 沙利度胺.

What are the documented applications of thalidomide?

Recorded applications: MEDICATION, Angiogenesis Inhibitors, Immunosuppressive Agents, Leprostatic Agents, Teratogens, For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma.

Which category does thalidomide belong to?

Category: Organic Chemicals.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for thalidomide (CAS 50-35-1), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number50-35-1
PubChem CID5426
Molecular formulaC13H10N2O4
IUPAC name2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
UNII (FDA)4Z8R6ORS6L

Computed descriptors

Molecular Weight258.23
XLogP30.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass258.06405680
Monoisotopic Mass258.06405680
Topological Polar Surface Area83.6
Heavy Atom Count19

Physicochemical values on record

Melting Point516 to 520 °F (NTP, 1992)
Melting Point270
Melting Point270 °C
Solubility545
Solubility2.55e+00 g/L
LogP0.33
LogPlog Kow = 0.33
LogP0.3
LogP0.49

Documented uses on record

    Angiogenesis Inhibitors; Immunosuppressive Agents; Leprostatic Agents; TeratogensFor the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma.

    Synonyms and trade names

    thalidomide; 50-35-1; Thalomid; Contergan; Pantosediv; Distaval; Softenon; Kevadon; Psychotablets; Algosediv; Calmorex; Neosedyn; Profarmil; Quetimid; Sedisperil; Imidene

    GHS hazard classification

    Reported hazard statementsH302 (88.2%), H360 (92.1%)

    H302 (88.2%): Harmful if swallowed [Warning Acute toxicity, oral]

    H360 (92.1%): May damage fertility or the unborn child [Danger Reproductive toxicity]

    What the public record says

    thalidomide · CAS 50-35-1 · C13H10N2O4. UNII 4Z8R6ORS6L. Melting Point: 516 to 520 °F (NTP, 1992); Melting Point: 270; Melting Point: 270 °C.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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