Talniflumate

Independent reference data for Talniflumate (CAS 66898-62-2), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

Talnifumate is a phthalidyl ester of nifumic acid, which has potent analgesic and anti-inflammatory effects and is widely used to treat inflammatory disorders, such as rheumatoid arthritis and osteoarthritis, and has also been studied for the management of cystic fibrosis.In 12 subjects after a single oral administration, total plasma clearance of the main metabolite, niflumic acid, averaged 45 ml/min giving a distribution volume of 0.12 l/kg on average.

Synonyms and trade names

Talniflumate; 66898-62-2; Somalgen; Talniflumato; BA 7602-06; Talniflumatum; DTXSID3046740; Ba-7602-06; JFK78S0U9S; DTXCID1026740; RefChem:891040; 3-oxo-1,3-dihydro-2-benzofuran-1-yl 2-((3-(trifluoromethyl)phenyl)amino)pyridine-3-carboxylate; Lomucin; Talniflumatum [INN-Latin]; UNII-JFK78S0U9S; 3-Oxo-1,3-dihydroisobenzofuran-1-yl 2-((3-(trifluoromethyl)phenyl)amino)nicotinate

What the public record says

Talniflumate · CAS 66898-62-2 · C21H13F3N2O4. UNII JFK78S0U9S. Boiling Point: 454; Melting Point: 177; LogP: 4.47.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.