sulfamethizole (CAS 144-82-1) — formula C9H10N4O2S2, molecular weight 270.3; category organic chemicals.
| CAS Number | 144-82-1 |
|---|---|
| Molecular Formula | C9H10N4O2S2 |
| Molecular Weight | 270.3 |
| Melting Point | 406 °F (NTP, 1992) |
| LogP | 0.54 |
| Applications | Uses: THERAP CAT: Antibacterial, THERAP CAT (VET): Antibacterial, MEDICATION, MEDICATION (VET), Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients, Pharmaceuticals -> Animal Drugs -> Approved in Taiwan, Methods of Manufacturing: Prepared by the reaction of acetaldehyde thiosemicarbazone with p-acetylaminobenzenesulfonyl chloride in pyridine., Formulations, Preparations: Oral tablets: 500 mg (sulfamethizole), Thiosulfil Forte (scored), Wyeth-Ayerst, MARKETED AS A 4% AQUEOUS SOLN, PH 7.3-7.4., SODIUM SALT, SULFAMETHIZOLE IS AVAILABLE IN TABLETS CONTAINING 250, 500, OR 1000 MG & IN SUSPENSIONS OF 250 MG, 5 ML OR 500 MG, 5 ML., Thiosnifil-A (Ayerst), Proklar (O'Neal, Jones & Feldman), component of Azotrex (Bristol), and component of Suladyne (Reid-Provident)., General Manufacturing Information: Benzenesulfonamide, 4-amino-N-(5-methyl-1, 3, 4-thiadiazol-2-yl)-: ACTIVE |
| Category | Organic Chemicals |
Documented applications: Uses: THERAP CAT: Antibacterial, THERAP CAT (VET): Antibacterial, MEDICATION, MEDICATION (VET), Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients, Pharmaceuticals -> Animal Drugs -> Approved in Taiwan, Methods of Manufacturing: Prepared by the reaction of acetaldehyde thiosemicarbazone with p-acetylaminobenzenesulfonyl chloride in pyridine., Formulations, Preparations: Oral tablets: 500 mg (sulfamethizole), Thiosulfil Forte (scored), Wyeth-Ayerst, MARKETED AS A 4% AQUEOUS SOLN, PH 7.3-7.4., SODIUM SALT, SULFAMETHIZOLE IS AVAILABLE IN TABLETS CONTAINING 250, 500, OR 1000 MG & IN SUSPENSIONS OF 250 MG, 5 ML OR 500 MG, 5 ML., Thiosnifil-A (Ayerst), Proklar (O'Neal, Jones & Feldman), component of Azotrex (Bristol), and component of Suladyne (Reid-Provident)., General Manufacturing Information: Benzenesulfonamide, 4-amino-N-(5-methyl-1, 3, 4-thiadiazol-2-yl)-: ACTIVE.
sulfamethizole is a carbon-based organic compound with CAS registry number 144-82-1 and molecular formula C9H10N4O2S2 (molecular weight 270.3), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 144-82-1
Its molecular formula C9H10N4O2S2 comprises 9 C, 10 H, 4 N, 2 O, 2 S atoms.
Also known as: sulfamethizole · 磺胺二甲唑
Category: organic chemicals
The CAS registry number of sulfamethizole is 144-82-1.
Molecular formula C9H10N4O2S2, molecular weight 270.3.
It is also registered under: sulfamethizole, 磺胺二甲唑.
Recorded applications: Uses: THERAP CAT: Antibacterial, THERAP CAT (VET): Antibacterial, MEDICATION, MEDICATION (VET), Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients, Pharmaceuticals -> Animal Drugs -> Approved in Taiwan, Methods of Manufacturing: Prepared by the reaction of acetaldehyde thiosemicarbazone with p-acetylaminobenzenesulfonyl chloride in pyridine., Formulations, Preparations: Oral tablets: 500 mg (sulfamethizole), Thiosulfil Forte (scored), Wyeth-Ayerst, MARKETED AS A 4% AQUEOUS SOLN, PH 7.3-7.4., SODIUM SALT, SULFAMETHIZOLE IS AVAILABLE IN TABLETS CONTAINING 250, 500, OR 1000 MG & IN SUSPENSIONS OF 250 MG, 5 ML OR 500 MG, 5 ML., Thiosnifil-A (Ayerst), Proklar (O'Neal, Jones & Feldman), component of Azotrex (Bristol), and component of Suladyne (Reid-Provident)., General Manufacturing Information: Benzenesulfonamide, 4-amino-N-(5-methyl-1, 3, 4-thiadiazol-2-yl)-: ACTIVE.
Category: Organic Chemicals.
Independent reference data for sulfamethizole (CAS 144-82-1), compiled from public chemistry databases.
| CAS Registry Number | 144-82-1 |
|---|---|
| PubChem CID | 5328 |
| Molecular formula | C9H10N4O2S2 |
| IUPAC name | 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide |
| UNII (FDA) | 25W8454H16 |
| Molecular Weight | 270.3 |
|---|---|
| XLogP3 | 0.5 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 3 |
| Exact Mass | 270.02451792 |
| Monoisotopic Mass | 270.02451792 |
| Topological Polar Surface Area | 135 |
| Heavy Atom Count | 17 |
| Melting Point | 406 °F (NTP, 1992) |
|---|---|
| Melting Point | 208 |
| Melting Point | 210 °C |
| Melting Point | 208 °C |
| Solubility | 1050 |
| Solubility | In water, 105 mg/L at 37 °C |
| Solubility | 6.11e-01 g/L |
| LogP | 0.54 |
| LogP | log Kow = 0.54 |
| LogP | 0.9 |
sulfamethizole; 144-82-1; Sulfamethizol; Sulphamethizole; Thiosulfil; 4-Amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide; Rufol; Sulfamethylthiadiazole; Sulfurine; Urosulfin; Methazol; Microsul; Proklar; Sulfametizol; Ayerlucil; Sulfapyelon
| Reported hazard statements | H317 (98.8%) |
|---|
H317 (98.8%): May cause an allergic skin reaction [Warning Sensitization, Skin]
P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501 (click each P-code to see the statement)
sulfamethizole · CAS 144-82-1 · C9H10N4O2S2. UNII 25W8454H16. Melting Point: 406 °F (NTP, 1992); Melting Point: 208; Melting Point: 210 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 磺胺二甲唑