丁二酸酐（CAS 108-30-5）：分子式 C4H4O3、分子量 100.07；类别 医药中间体。
| CAS号 | 108-30-5 |
|---|---|
| 分子式 | C4H4O3 |
| 分子量 | 100.07 |
| 熔点 | 247.3 °F (NTP, 1992) |
| 沸点 | 502 °F at 760 mmHg (NTP, 1992) |
| LogP | -0.5 |
| 应用领域 | Uses: Used as an acidulant and dehydrating agent (food processing)、cross-linking agent (epoxy resins and ion exchange membranes)、and in gas and water treatment、Also used to make adhesives、paint drying oils、dyes、pharmaceuticals、esters、elastomers (cable coverings and extruded articles)、hardeners for resins、starch modifiers in foods、succinylated monoglyceride food emulsifiers、silver haloid photographic emulsions、detergents、cosmetics、plant growth regulators、textiles、surface-active agents、lubricant additives、fire-retardants for paper、insect repellants、and herbicides、[HSDB]、Textiles (Fiber & Fabric Manufacturing) [Category: Industry]、Sewer and Wastewater Treatment [Category: Industry]、Plastic Composites Manufacturing [Category: Industry]、Acidulant in processed foods、Dehydrating agent in dry food mixtures、Chemical intermediate for adhesives、elastomers for special tubings、cable coverings、and extruded articles.、Manufacture of chemicals、hardener for resins、starch modifier in foods.、For more Uses (Complete) data for SUCCINIC ANHYDRIDE (9 total)、please visit the HSDB record page.、Industry Uses: Corrosion inhibitor、Not Known or Reasonably Ascertainable、pH regulating agent、Other、Methods of Manufacturing: Hydrogenation of maleic anhydride or fumaric acid、heating of succinic acid at elevated temperature and pressure.、...By treating succinic acid with diketene、succinyl chloride or acetic anhydride、or by reacting diethyl ester with boron chloride.、... Warming succinic acid with acetic anhydride、acetyl chloride、or phosphorus oxychloride.、Succinic anhydride is manufactured by catalytic hydrogenation of maleic anhydride. In the most widely used commercial process this reaction is performed in the liquid phase、at temperatures of 120-180 °C and at moderate pressures、in the range of 500-4000 kPa (72-580 psi). Catalysts mentioned in the patent literature include nickel、Raney nickel、palladium on different carriers、and palladium complexes.、Formulations、Preparations: Grade: distilled.、...Available in US as commercial grade containing at least 99.5% of pure chemical、with maximum of 0.5% unsaturated compound...0.15% chlorides、0.04% sulfates...and 20 mg、kg heavy metals.、Flake、U.S. Production: 2023: 50、000 - <250、000 lb、2022: 1、000、000 - <2、500、2021: 400、000 - <550、2020: 550、000 - <700、2、5-Furandione、dihydro- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、(1972) PROBABLY GREATER THAN 4.54X10+5 G、(1975) PROBABLY GREATER THAN 9.08X10+5 G、(1986) No Data、For more U.S. Production (Complete) data for SUCCINIC ANHYDRIDE (9 total)、U.S. Imports: (1972) 4.5X10+6 G (PRINCPL CUSTOMS DISTS)、(1974) 2.7X10+6 G (PRINCPL CUSTOMS DISTS)、(1984) 1.99X10+9 g、Organic acid anhydrides、U.S. Exports: (1972) No Data、(1975) No Data、(1984) 2.07X10+8 g、Anhydrides、Acyl Halides、and their derivatives、General Manufacturing Information: Plastics Material and Resin Manufacturing、Textiles、apparel、and leather manufacturing、Asphalt Paving、Roofing、and Coating Materials Manufacturing、dihydro-: ACTIVE、Anhydrous dentifrices containing an acid anhydride to maintain sweetener stability reported. Toothpaste containing 0.50 parts succinic anhydride is an example.、Succinic anhydride is...very useful dehydrating agent for removal of small amounts of moisture in...dry food mixtures which are later to be admixed with water. ...It is capable of taking up 20% of its weight of water、and the acid formed is desirable flavoring agent in many foods. |
| 类别 | 医药中间体 |
登记用途：Uses: Used as an acidulant and dehydrating agent (food processing)、cross-linking agent (epoxy resins and ion exchange membranes)、and in gas and water treatment、Also used to make adhesives、paint drying oils、dyes、pharmaceuticals、esters、elastomers (cable coverings and extruded articles)、hardeners for resins、starch modifiers in foods、succinylated monoglyceride food emulsifiers、silver haloid photographic emulsions、detergents、cosmetics、plant growth regulators、textiles、surface-active agents、lubricant additives、fire-retardants for paper、insect repellants、and herbicides、[HSDB]、Textiles (Fiber & Fabric Manufacturing) [Category: Industry]、Sewer and Wastewater Treatment [Category: Industry]、Plastic Composites Manufacturing [Category: Industry]、Acidulant in processed foods、Dehydrating agent in dry food mixtures、Chemical intermediate for adhesives、elastomers for special tubings、cable coverings、and extruded articles.、Manufacture of chemicals、hardener for resins、starch modifier in foods.、For more Uses (Complete) data for SUCCINIC ANHYDRIDE (9 total)、please visit the HSDB record page.、Industry Uses: Corrosion inhibitor、Not Known or Reasonably Ascertainable、pH regulating agent、Other、Methods of Manufacturing: Hydrogenation of maleic anhydride or fumaric acid、heating of succinic acid at elevated temperature and pressure.、...By treating succinic acid with diketene、succinyl chloride or acetic anhydride、or by reacting diethyl ester with boron chloride.、... Warming succinic acid with acetic anhydride、acetyl chloride、or phosphorus oxychloride.、Succinic anhydride is manufactured by catalytic hydrogenation of maleic anhydride. In the most widely used commercial process this reaction is performed in the liquid phase、at temperatures of 120-180 °C and at moderate pressures、in the range of 500-4000 kPa (72-580 psi). Catalysts mentioned in the patent literature include nickel、Raney nickel、palladium on different carriers、and palladium complexes.、Formulations、Preparations: Grade: distilled.、...Available in US as commercial grade containing at least 99.5% of pure chemical、with maximum of 0.5% unsaturated compound...0.15% chlorides、0.04% sulfates...and 20 mg、kg heavy metals.、Flake、U.S. Production: 2023: 50、000 - <250、000 lb、2022: 1、000、000 - <2、500、2021: 400、000 - <550、2020: 550、000 - <700、2、5-Furandione、dihydro- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、(1972) PROBABLY GREATER THAN 4.54X10+5 G、(1975) PROBABLY GREATER THAN 9.08X10+5 G、(1986) No Data、For more U.S. Production (Complete) data for SUCCINIC ANHYDRIDE (9 total)、U.S. Imports: (1972) 4.5X10+6 G (PRINCPL CUSTOMS DISTS)、(1974) 2.7X10+6 G (PRINCPL CUSTOMS DISTS)、(1984) 1.99X10+9 g、Organic acid anhydrides、U.S. Exports: (1972) No Data、(1975) No Data、(1984) 2.07X10+8 g、Anhydrides、Acyl Halides、and their derivatives、General Manufacturing Information: Plastics Material and Resin Manufacturing、Textiles、apparel、and leather manufacturing、Asphalt Paving、Roofing、and Coating Materials Manufacturing、dihydro-: ACTIVE、Anhydrous dentifrices containing an acid anhydride to maintain sweetener stability reported. Toothpaste containing 0.50 parts succinic anhydride is an example.、Succinic anhydride is...very useful dehydrating agent for removal of small amounts of moisture in...dry food mixtures which are later to be admixed with water. ...It is capable of taking up 20% of its weight of water、and the acid formed is desirable flavoring agent in many foods.。
丁二酸酐 是一种化工化合物，登记 CAS 号为 108-30-5，分子式 C4H4O3（分子量 100.07），归属于医药中间体大类化工原料。
登记 CAS 号：108-30-5
其分子式 C4H4O3 由 4 个碳、4 个氢、3 个氧 组成。
别名/同义词：丁二酸酐 · Succinic Anhydride
所属分类：医药中间体
丁二酸酐 的 CAS 登记号为 108-30-5。
分子式 C4H4O3，分子量 100.07。
别名/同义词：丁二酸酐、Succinic Anhydride。
登记用途：Uses: Used as an acidulant and dehydrating agent (food processing)、cross-linking agent (epoxy resins and ion exchange membranes)、and in gas and water treatment、Also used to make adhesives、paint drying oils、dyes、pharmaceuticals、esters、elastomers (cable coverings and extruded articles)、hardeners for resins、starch modifiers in foods、succinylated monoglyceride food emulsifiers、silver haloid photographic emulsions、detergents、cosmetics、plant growth regulators、textiles、surface-active agents、lubricant additives、fire-retardants for paper、insect repellants、and herbicides、[HSDB]、Textiles (Fiber & Fabric Manufacturing) [Category: Industry]、Sewer and Wastewater Treatment [Category: Industry]、Plastic Composites Manufacturing [Category: Industry]、Acidulant in processed foods、Dehydrating agent in dry food mixtures、Chemical intermediate for adhesives、elastomers for special tubings、cable coverings、and extruded articles.、Manufacture of chemicals、hardener for resins、starch modifier in foods.、For more Uses (Complete) data for SUCCINIC ANHYDRIDE (9 total)、please visit the HSDB record page.、Industry Uses: Corrosion inhibitor、Not Known or Reasonably Ascertainable、pH regulating agent、Other、Methods of Manufacturing: Hydrogenation of maleic anhydride or fumaric acid、heating of succinic acid at elevated temperature and pressure.、...By treating succinic acid with diketene、succinyl chloride or acetic anhydride、or by reacting diethyl ester with boron chloride.、... Warming succinic acid with acetic anhydride、acetyl chloride、or phosphorus oxychloride.、Succinic anhydride is manufactured by catalytic hydrogenation of maleic anhydride. In the most widely used commercial process this reaction is performed in the liquid phase、at temperatures of 120-180 °C and at moderate pressures、in the range of 500-4000 kPa (72-580 psi). Catalysts mentioned in the patent literature include nickel、Raney nickel、palladium on different carriers、and palladium complexes.、Formulations、Preparations: Grade: distilled.、...Available in US as commercial grade containing at least 99.5% of pure chemical、with maximum of 0.5% unsaturated compound...0.15% chlorides、0.04% sulfates...and 20 mg、kg heavy metals.、Flake、U.S. Production: 2023: 50、000 - <250、000 lb、2022: 1、000、000 - <2、500、2021: 400、000 - <550、2020: 550、000 - <700、2、5-Furandione、dihydro- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、(1972) PROBABLY GREATER THAN 4.54X10+5 G、(1975) PROBABLY GREATER THAN 9.08X10+5 G、(1986) No Data、For more U.S. Production (Complete) data for SUCCINIC ANHYDRIDE (9 total)、U.S. Imports: (1972) 4.5X10+6 G (PRINCPL CUSTOMS DISTS)、(1974) 2.7X10+6 G (PRINCPL CUSTOMS DISTS)、(1984) 1.99X10+9 g、Organic acid anhydrides、U.S. Exports: (1972) No Data、(1975) No Data、(1984) 2.07X10+8 g、Anhydrides、Acyl Halides、and their derivatives、General Manufacturing Information: Plastics Material and Resin Manufacturing、Textiles、apparel、and leather manufacturing、Asphalt Paving、Roofing、and Coating Materials Manufacturing、dihydro-: ACTIVE、Anhydrous dentifrices containing an acid anhydride to maintain sweetener stability reported. Toothpaste containing 0.50 parts succinic anhydride is an example.、Succinic anhydride is...very useful dehydrating agent for removal of small amounts of moisture in...dry food mixtures which are later to be admixed with water. ...It is capable of taking up 20% of its weight of water、and the acid formed is desirable flavoring agent in many foods.。
所属分类：医药中间体。
丁二酸酐（CAS 108-30-5）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 108-30-5 |
|---|---|
| PubChem CID | 7922 |
| Molecular formula | C4H4O3 |
| IUPAC name | oxolane-2,5-dione |
| UNII (FDA) | 6RF4O17Z8J |
| Molecular Weight | 100.07 |
|---|---|
| XLogP3 | -0.5 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 0 |
| Exact Mass | 100.016043985 |
| Monoisotopic Mass | 100.016043985 |
| Topological Polar Surface Area | 43.4 |
| Heavy Atom Count | 7 |
| Boiling Point | 502 °F at 760 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | 261 °C at 760 mm Hg |
| Boiling Point | 261 °C |
| Boiling Point | 261 °C @760 [mm Hg] |
| Melting Point | 247.3 °F (NTP, 1992) |
| Melting Point | 119.6 °C |
| Melting Point | 119 °C |
| Flash Point | 157 °C |
| Density | 1.104 @25 °C |
| Vapor Pressure | 0.0015 [mmHg] |
SUCCINIC ANHYDRIDE; 108-30-5; oxolane-2,5-dione; Succinic acid anhydride; Succinyl oxide; Dihydro-2,5-furandione; 2,5-Diketotetrahydrofuran; Butanedioic anhydride; Succinyl anhydride; 2,5-Furandione, dihydro-; Rikacid SA; Tetrahydro-2,5-dioxofuran; 2,5-Dioxotetrahydrofuran; Tetrahydro-2,5-furandione; NCI-C55696; DTXSID7021287
| Regulatory & Food Contact | FDA Substance added to food: Use unspecified FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS |
|---|---|
| GHS notification summary | 0.2% (2 / 1275) |
| GHS notification summary | 0.2% (2 / 1275) |
|---|---|
| Reported hazard statements | H302, H314, H317, H318, H334, H319 (81.1%), H335 (90.6%), H402 |
H302: Harmful if swallowed [Warning Acute toxicity, oral]
H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
Succinic Anhydride · CAS 108-30-5 · C4H4O3. UNII 6RF4O17Z8J. Boiling Point: 502 °F at 760 mmHg (NTP, 1992); Boiling Point: 261 °C at 760 mm Hg; Boiling Point: 261 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Succinic Anhydride