Ritonavir (CAS 155213-67-5) — formula C37H48N6O5S2, molecular weight 720.9; category organic chemicals.
| CAS Number | 155213-67-5 |
|---|---|
| Molecular Formula | C37H48N6O5S2 |
| Molecular Weight | 720.9 |
| LogP | 3.9 |
| Applications | Uses: MEDICATION, Antiviral, Use (kg) in Switzerland (2009): >100, Use (kg, approx.) in Germany (2009): >1000, Use (kg) in USA (2002): 2340, Consumption (g per capita) in Switzerland (2009): 0.013, Consumption (g per capita, approx.) in Germany (2009): 0.012, Consumption (g per capita) in the USA (2002): 0.0083, Excretion rate: 0.465, Calculated removal (%): 93, Methods of Manufacturing: Preparation: ... D.J. Kempf et al, US 5541206 (1994, 1996 both to Abbott), Formulations, Preparations: Oral: Capsules, liquid-filled, 100 mg, Norvir Softgel (with alcohol and polyoxyl 35 castor oil), Abbott, Solution 80 mg, ml, Norvir (with alcohol polyoxyl 35 castor oil, and propylene glycol) |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION, Antiviral, Use (kg) in Switzerland (2009): >100, Use (kg, approx.) in Germany (2009): >1000, Use (kg) in USA (2002): 2340, Consumption (g per capita) in Switzerland (2009): 0.013, Consumption (g per capita, approx.) in Germany (2009): 0.012, Consumption (g per capita) in the USA (2002): 0.0083, Excretion rate: 0.465, Calculated removal (%): 93, Methods of Manufacturing: Preparation: ... D.J. Kempf et al, US 5541206 (1994, 1996 both to Abbott), Formulations, Preparations: Oral: Capsules, liquid-filled, 100 mg, Norvir Softgel (with alcohol and polyoxyl 35 castor oil), Abbott, Solution 80 mg, ml, Norvir (with alcohol polyoxyl 35 castor oil, and propylene glycol).
Ritonavir is a carbon-based organic compound with CAS registry number 155213-67-5 and molecular formula C37H48N6O5S2 (molecular weight 720.9), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 155213-67-5
Its molecular formula C37H48N6O5S2 comprises 37 C, 48 H, 6 N, 5 O, 2 S atoms.
Also known as: Ritonavir
Category: organic chemicals
The CAS registry number of Ritonavir is 155213-67-5.
Molecular formula C37H48N6O5S2, molecular weight 720.9.
It is also registered under: Ritonavir.
Recorded applications: Uses: MEDICATION, Antiviral, Use (kg) in Switzerland (2009): >100, Use (kg, approx.) in Germany (2009): >1000, Use (kg) in USA (2002): 2340, Consumption (g per capita) in Switzerland (2009): 0.013, Consumption (g per capita, approx.) in Germany (2009): 0.012, Consumption (g per capita) in the USA (2002): 0.0083, Excretion rate: 0.465, Calculated removal (%): 93, Methods of Manufacturing: Preparation: ... D.J. Kempf et al, US 5541206 (1994, 1996 both to Abbott), Formulations, Preparations: Oral: Capsules, liquid-filled, 100 mg, Norvir Softgel (with alcohol and polyoxyl 35 castor oil), Abbott, Solution 80 mg, ml, Norvir (with alcohol polyoxyl 35 castor oil, and propylene glycol).
Category: Organic Chemicals.
Independent reference data for Ritonavir (CAS 155213-67-5), compiled from public chemistry databases.
| CAS Registry Number | 155213-67-5 |
|---|---|
| PubChem CID | 392622 |
| Molecular formula | C37H48N6O5S2 |
| IUPAC name | 1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate |
| UNII (FDA) | O3J8G9O825 |
| Molecular Weight | 720.9 |
|---|---|
| XLogP3 | 6 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 18 |
| Exact Mass | 720.31276100 |
| Monoisotopic Mass | 720.31276100 |
| Topological Polar Surface Area | 202 |
| Heavy Atom Count | 50 |
| Solubility | 1.26e-03 g/L |
|---|---|
| Vapor Pressure | 1.1X10-27 mm Hg @ 25 °C /Estimated/ |
| LogP | 3.9 |
ritonavir; 155213-67-5; Norvir; ABT-538; A-84538; Abbott 84538; ABBOTT-84538; Empetus; Ritomune; Ritovir; Viekirax; Viriton; Ritonavirum; ABT538; DTXSID1048627; CHEBI:45409
| Reported hazard statements | H302, H312, H332 (41.7%), H319 (52.1%), H351 (55.2%), H361 (52.1%) |
|---|
H302+H312+H332 (41.7%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]
H302 (88.5%): Harmful if swallowed [Warning Acute toxicity, oral]
Ritonavir · CAS 155213-67-5 · C37H48N6O5S2. UNII O3J8G9O825. Solubility: 1.26e-03 g/L; Vapor Pressure: 1.1X10-27 mm Hg @ 25 °C /Estimated/; LogP: 3.9.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: Ritonavir