Pyrilamine

Description

Pyrilamine · CAS 91-84-9 · C17H23N3O. UNII HPE317O9TL. Boiling Point: 334 to 342 °F at 0.06 mmHg (NTP, 1992); Boiling Point: 201 °C @ 5 MM HG; Solubility: 7.81e-01 g/L.

Identification

CAS Registry Number	91-84-9
PubChem CID	4992
Molecular formula	C17H23N3O
IUPAC name	N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine
UNII (FDA)	HPE317O9TL

Computed Descriptors

Molecular Weight	285.4
XLogP3	3.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	285.184112366
Monoisotopic Mass	285.184112366
Topological Polar Surface Area	28.6
Heavy Atom Count	21
Formal Charge	0

Physical & Chemical Properties

Boiling Point	334 to 342 °F at 0.06 mmHg (NTP, 1992)
Boiling Point	201 °C @ 5 MM HG
Solubility	7.81e-01 g/L
LogP	3.27
LogP	2.85
Dissociation Constants	8.85 (at 20 °C)

Physical description & handling notes

• Pyrilamine is a viscous brown liquid. (NTP, 1992)
• Solid
• OILY LIQUID
• MELTING POINT: 143-143.5 °C /HYDROCHLORIDE/, 100-101 °C /MALEATE/
• less than 1 mg/mL at 68 °F (NTP, 1992)
• 1 G DISSOLVES IN ABOUT 0.4 ML WATER; SLIGHTLY SOL IN BENZENE, ETHER; 1 G DISSOLVES IN ABOUT 15 ML ABS ALCOHOL /MALEATE/

GHS Hazard Classification

Reported hazard statements	H302 (100%), H334 (88.6%)

Documented Uses

• PREPARED BY CONDENSING 2-(N-P-METHOXYBENZYL)-AMINOPYRIDINE WITH DIMETHYLAMINOETHYL CHLORIDE, OR BY CONDENSING N,N-DIMETHYLAMINOETHYL-ALPHA-AMINOPYRIDINE WITH P-METHOXYBENZYL CHLORIDE IN THE PRESENCE OF SODAMIDE OR LITHAMIDE.
• TREATMENT OF THE PURE BASE WITH AN EQUIMOLAR QUANTITY OF MALEIC ACID YIELDS THE MALEATE. /MALEATE/
• (1977) PROBABLY MORE THAN 4.54X10+5 G-MALEATE
• (1979) PROBABLY MORE THAN 4.54X10+5 G-MALEATE
• (1977) 4.7X10+6 G-PRINCPL CUSTMS DISTS-MALEATE
• (1979) 3.2X10+7 G-PRINCPL CUSTMS DISTS-MALEATE

Synonyms

Mepyramine; pyrilamine; 91-84-9; Pyranisamine; Dorantamin; Mepiramine; Neoantergan; Anhistabs; Anhistol; Antalergan; Antallergan; Antamine; Copsamine; Harvamine; Histacap; Histalon

Frequently Asked Questions

What are the CAS number and molecular formula of Pyrilamine?

CAS 91-84-9; molecular formula C17H23N3O; molecular weight — g/mol.

What other names is Pyrilamine known by?

Mepyramine, pyrilamine, 91-84-9, Pyranisamine, Dorantamin, Mepiramine.

Is Pyrilamine classified as hazardous?

Hazard statements reported: H302, H334.

What are the key physical properties of Pyrilamine?

Boiling Point: 334 to 342 °F at 0.06 mmHg (NTP, 1992); Boiling Point: 201 °C @ 5 MM HG; Solubility: 7.81e-01 g/L; LogP: 3.27.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.