Pyrido[2,3-d]pyrimidin-2(1H)-one,6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-,(1R)- (CAS 2296729-00-3) — formula C30H30F2N6O3, molecular weight 560.6; category organic chemicals.
| CAS Number | 2296729-00-3 |
|---|---|
| Molecular Formula | C30H30F2N6O3 |
| Molecular Weight | 560.6 |
| LogP | 4 |
| Category | Organic Chemicals |
Pyrido[2,3-d]pyrimidin-2(1H)-one,6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-,(1R)- is a carbon-based organic compound with CAS registry number 2296729-00-3 and molecular formula C30H30F2N6O3 (molecular weight 560.6), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 2296729-00-3
Its molecular formula C30H30F2N6O3 comprises 30 C, 30 H, 2 F, 6 N, 3 O atoms.
Also known as: Pyrido[2,3-d]pyrimidin-2(1H)-one,6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-,(1R)- · 索托拉西布
Category: organic chemicals
The CAS registry number of Pyrido[2,3-d]pyrimidin-2(1H)-one,6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-,(1R)- is 2296729-00-3.
Molecular formula C30H30F2N6O3, molecular weight 560.6.
It is also registered under: Pyrido[2,3-d]pyrimidin-2(1H)-one,6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-,(1R)-, 索托拉西布.
Category: Organic Chemicals.
Independent reference data for Pyrido[2,3-d]pyrimidin-2(1H)-one,6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-,(1R)- (CAS 2296729-00-3), compiled from public chemistry databases.
| CAS 号 | 2296729-00-3 |
|---|---|
| PubChem CID | 137278711 |
| 分子式 | C30H30F2N6O3 |
| IUPAC 名称 | 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-propan-2-yl-3-pyridinyl)-4-[(2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one |
| UNII（FDA） | 2B2VM6UC8G |
| Molecular Weight | 560.6 |
|---|---|
| XLogP3 | 4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 5 |
| Exact Mass | 560.23474516 |
| Monoisotopic Mass | 560.23474516 |
| Topological Polar Surface Area | 102 |
| Heavy Atom Count | 41 |
| Solubility | 1.3 |
|---|---|
| Dissociation Constants | 8.06, 4.56 |
Sotorasib; AMG-510; 2296729-00-3; AMG510; Lumakras; AMG 510; Kras G12C inhibitor 9; Kras mutant-targeting AMG 510; 2B2VM6UC8G; CHEBI:178199; RefChem:56869; 2252403-56-6; AMG-510 racemate; SOTORASIB RACEMATE; Lumykras; Sotorasib [INN]
索托拉西布 · CAS 2296729-00-3 · C30H30F2N6O3. UNII 2B2VM6UC8G. Solubility: 1.3; Dissociation Constants: 8.06, 4.56.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 索托拉西布