procarbazine hydrochloride (CAS 366-70-1) — formula C12H19N3O, molecular weight 221.30; category organic chemicals.
| CAS Number | 366-70-1 |
|---|---|
| Molecular Formula | C12H19N3O |
| Molecular Weight | 221.30 |
| Melting Point | 223 |
| LogP | 0.06 |
| Applications | Uses: Antineoplastic, MEDICATION (VET), MEDICATION, Use (kg, approx.) in Germany (2009): >10, Consumption (g per capita, approx.) in Germany (2009): 0.000122, Calculated removal (%): 22, For use with other anticancer drugs for the treatment of stage III and stage IV Hodgkin's disease., Use Classification: Pharmaceuticals, Methods of Manufacturing: p-toluic acid + methyl hydrazine + isopropylamine (side-chain bromination, amine formation, amide formation)., Formulations, Preparations: Oral: Capsules: 50 mg (of procarbazine), Matulane (with parabens), Sigma-Tau, U.S. Production: (1976) NOT PRODUCED COMMERCIALLY IN US, (1978) NOT PRODUCED COMMERCIALLY IN US, General Manufacturing Information: PATENTS: US PATENT 3, 520, 926., HYDROCHLORIDE |
| Category | Organic Chemicals |
Documented applications: Uses: Antineoplastic, MEDICATION (VET), MEDICATION, Use (kg, approx.) in Germany (2009): >10, Consumption (g per capita, approx.) in Germany (2009): 0.000122, Calculated removal (%): 22, For use with other anticancer drugs for the treatment of stage III and stage IV Hodgkin's disease., Use Classification: Pharmaceuticals, Methods of Manufacturing: p-toluic acid + methyl hydrazine + isopropylamine (side-chain bromination, amine formation, amide formation)., Formulations, Preparations: Oral: Capsules: 50 mg (of procarbazine), Matulane (with parabens), Sigma-Tau, U.S. Production: (1976) NOT PRODUCED COMMERCIALLY IN US, (1978) NOT PRODUCED COMMERCIALLY IN US, General Manufacturing Information: PATENTS: US PATENT 3, 520, 926., HYDROCHLORIDE.
procarbazine hydrochloride is a carbon-based organic compound with CAS registry number 366-70-1 and molecular formula C12H19N3O (molecular weight 221.30), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 366-70-1
Its molecular formula C12H19N3O comprises 12 C, 19 H, 3 N, 1 O atoms.
Also known as: procarbazine hydrochloride · 盐酸丙卡巴肼
Category: organic chemicals
The CAS registry number of procarbazine hydrochloride is 366-70-1.
Molecular formula C12H19N3O, molecular weight 221.30.
It is also registered under: procarbazine hydrochloride, 盐酸丙卡巴肼.
Recorded applications: Uses: Antineoplastic, MEDICATION (VET), MEDICATION, Use (kg, approx.) in Germany (2009): >10, Consumption (g per capita, approx.) in Germany (2009): 0.000122, Calculated removal (%): 22, For use with other anticancer drugs for the treatment of stage III and stage IV Hodgkin's disease., Use Classification: Pharmaceuticals, Methods of Manufacturing: p-toluic acid + methyl hydrazine + isopropylamine (side-chain bromination, amine formation, amide formation)., Formulations, Preparations: Oral: Capsules: 50 mg (of procarbazine), Matulane (with parabens), Sigma-Tau, U.S. Production: (1976) NOT PRODUCED COMMERCIALLY IN US, (1978) NOT PRODUCED COMMERCIALLY IN US, General Manufacturing Information: PATENTS: US PATENT 3, 520, 926., HYDROCHLORIDE.
Category: Organic Chemicals.
Independent reference data for procarbazine hydrochloride (CAS 366-70-1), compiled from public chemistry databases.
| CAS Registry Number | 366-70-1 |
|---|---|
| PubChem CID | 4915 |
| Molecular formula | C12H19N3O |
| IUPAC name | 4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide |
| UNII (FDA) | 35S93Y190K |
| Molecular Weight | 221.30 |
|---|---|
| XLogP3 | 0.1 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 5 |
| Exact Mass | 221.152812238 |
| Monoisotopic Mass | 221.152812238 |
| Topological Polar Surface Area | 53.2 |
| Heavy Atom Count | 16 |
| Melting Point | 223 |
|---|---|
| Melting Point | 223 °C |
| Solubility | 1420 |
| Solubility | 2.28e-01 g/L |
| Vapor Pressure | 8.4X10-7 mm Hg @ 25 °C /Estimated/ |
| LogP | 0.06 |
| LogP | log Kow = 0.06 |
| LogP | 2.6 |
| Dissociation Constants | pKa = 6.6 |
procarbazine; 671-16-9; Procarbazin; Ibenzmethyzin; Procarbazina; Procarbazinum; Procarbacine; N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine; p-(2-Methylhydrazinomethyl)-N-isopropylbenzamide; 2-(p-Isopropylcarbamoylbenzyl)-1-methylhydrazine; N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide; 1-Methyl-2-(p-(isopropylcarbamoyl)benzyl)hydrazine; 4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide; Ro 4-6467; N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide; N-Isopropyl-p-(2-methylhydrazinomethyl)-benzamide
procarbazine hydrochloride · CAS 366-70-1 · C12H19N3O. UNII 35S93Y190K. Melting Point: 223; Melting Point: 223 °C; Solubility: 1420.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 盐酸丙卡巴肼