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泊马度胺

CAS 19171-19-8C13H11N3O4MW 273.24

泊马度胺(CAS 19171-19-8):分子式 C13H11N3O4、分子量 273.24;类别 医药中间体。

产品概览

CAS号19171-19-8
分子式C13H11N3O4
分子量273.24
LogP0.2
应用领域Uses: MEDICATION、Angiogenesis Inhibitors、Immunologic Factors、Methods of Manufacturing: Pomalidomide is synthesized in two main steps using commercially available well defined starting materials with acceptable specifications. The first step consists of a coupling reaction in which the starting materials react to form crude pomalidomide. The second step is a purification process consisting on filtration、crystallization and drying to obtain the final drug substance.、Preparation: G. W. Muller et al.、World Intellectual Property Organization patent 9803502、eidem、United States of America patent 6335349 (1998、2002 both to Celgene).、Formulations、Preparations: Table: Pomalidomide Preparations [Table#8206]
类别医药中间体

应用领域

登记用途:Uses: MEDICATION、Angiogenesis Inhibitors、Immunologic Factors、Methods of Manufacturing: Pomalidomide is synthesized in two main steps using commercially available well defined starting materials with acceptable specifications. The first step consists of a coupling reaction in which the starting materials react to form crude pomalidomide. The second step is a purification process consisting on filtration、crystallization and drying to obtain the final drug substance.、Preparation: G. W. Muller et al.、World Intellectual Property Organization patent 9803502、eidem、United States of America patent 6335349 (1998、2002 both to Celgene).、Formulations、Preparations: Table: Pomalidomide Preparations [Table#8206]。

技术档案

这个产品是什么

泊马度胺 是一种化工化合物,登记 CAS 号为 19171-19-8,分子式 C13H11N3O4(分子量 273.24),归属于医药中间体大类化工原料。

识别信息

登记 CAS 号:19171-19-8

其分子式 C13H11N3O4 由 13 个碳、11 个氢、3 个氮、4 个氧 组成。

别名/同义词:泊马度胺 · Pomalidomide

所属分类:医药中间体

常见问题

泊马度胺 的 CAS 号是多少?

泊马度胺 的 CAS 登记号为 19171-19-8。

泊马度胺 的分子式与分子量是多少?

分子式 C13H11N3O4,分子量 273.24。

泊马度胺 还有哪些别名?

别名/同义词:泊马度胺、Pomalidomide。

泊马度胺 的登记用途是什么?

登记用途:Uses: MEDICATION、Angiogenesis Inhibitors、Immunologic Factors、Methods of Manufacturing: Pomalidomide is synthesized in two main steps using commercially available well defined starting materials with acceptable specifications. The first step consists of a coupling reaction in which the starting materials react to form crude pomalidomide. The second step is a purification process consisting on filtration、crystallization and drying to obtain the final drug substance.、Preparation: G. W. Muller et al.、World Intellectual Property Organization patent 9803502、eidem、United States of America patent 6335349 (1998、2002 both to Celgene).、Formulations、Preparations: Table: Pomalidomide Preparations [Table#8206]。

泊马度胺 属于哪个分类?

所属分类:医药中间体。

PubChem 公开数据

泊马度胺(CAS 19171-19-8)的独立参考数据,整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number19171-19-8
PubChem CID134780
Molecular formulaC13H11N3O4
IUPAC name4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
UNII (FDA)D2UX06XLB5

计算分子描述符

Molecular Weight273.24
XLogP30.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass273.07495584
Monoisotopic Mass273.07495584
Topological Polar Surface Area110
Heavy Atom Count20

在册的记载用途

    Angiogenesis Inhibitors; Immunologic FactorsPomalidomide is synthesized in two main steps using commercially available well defined starting materials with acceptable specifications. The first step consists of a coupling reaction in which the starting materials react to form crude pomalidomide. The second step is a purification process consisting on filtration, crystallization and drying to obtain the final drug substance.

    同义词与商品名

    Pomalidomide; 19171-19-8; Actimid; Pomalyst; CC-4047; Imnovid; 4-Aminothalidomide; 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione; 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-; 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione; IMID-3; 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide; IMiD 3; CC 4047; Pomalidomida; D2UX06XLB5

    GHS 危害分类

    Reported hazard statementsH361 (10.8%), H373 (81.1%)

    H360FD (75.7%): May damage fertility; May damage the unborn child [Danger Reproductive toxicity]

    H361 (10.8%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

    公开数据库对它的描述

    Pomalidomide · CAS 19171-19-8 · C13H11N3O4. UNII D2UX06XLB5.

    物理形态与操作说明

    数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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