POLYDIMETHYLSILOXANE (CAS 8050-81-5) — formula C6H18O4Si3, molecular weight 238.46; category organic chemicals.
POLYDIMETHYLSILOXANE (CAS 8050-81-5) is a chemical raw material in the organic chemicals category. Its molecular formula C6H18O4Si3 comprises 6 C, 18 H, 4 O, 3 Si atoms. Its molecular weight is about 238.46. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 8050-81-5 |
|---|---|
| Molecular Formula | C6H18O4Si3 |
| Molecular Weight | 238.46 |
| Applications | The main use of simethicone as an excipient is as an antifoaming agent in pharmaceutical manufacturing processes, A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base, Antifoaming ingredient in cosmetics |
| Category | Organic Chemicals|Surfactants|Food Processing Aids|Defoamers |
Documented applications: The main use of simethicone as an excipient is as an antifoaming agent in pharmaceutical manufacturing processes, A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base, Antifoaming ingredient in cosmetics.
POLYDIMETHYLSILOXANE is a carbon-based organic compound with CAS registry number 8050-81-5 and molecular formula C6H18O4Si3 (molecular weight 238.46), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 8050-81-5
Its molecular formula C6H18O4Si3 comprises 6 C, 18 H, 4 O, 3 Si atoms.
Also known as: POLYDIMETHYLSILOXANE · Simethicone
Category: organic chemicals / surfactants / food additives / chemical
The CAS registry number of POLYDIMETHYLSILOXANE is 8050-81-5.
Molecular formula C6H18O4Si3, molecular weight 238.46.
It is also registered under: POLYDIMETHYLSILOXANE, Simethicone.
Recorded applications: The main use of simethicone as an excipient is as an antifoaming agent in pharmaceutical manufacturing processes, A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base, Antifoaming ingredient in cosmetics.
Category: Organic Chemicals / Surfactants / Food Processing Aids / Defoamers.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for POLYDIMETHYLSILOXANE (CAS 8050-81-5), compiled from public chemistry databases.
| CAS Registry Number | 8050-81-5 |
|---|---|
| PubChem CID | 6433516 |
| Molecular formula | C6H18O4Si3 |
| IUPAC name | dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane |
| UNII (FDA) | SIMETICONE |
| Molecular Weight | 238.46 |
|---|---|
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 238.05128865 |
| Monoisotopic Mass | 238.05128865 |
| Topological Polar Surface Area | 52.6 |
| Heavy Atom Count | 13 |
Simethicone; 8050-81-5; Sentry Simethicone; Mylanta Gas Relief; Mylicon Infant's Drops; Sentry Simethicone Emulsion; DTXSID00904918; RefChem:886342; 3,3,5,5-tetramethyl-2,4-dioxa-3,5-disilahexane; silanedione; 617-098-1; dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane; Simethicon; Simethicone(200); Simethicone(500); SIMETICONE; C6H18O4Si3
| Regulatory & Food Contact | ANTICAKING_AGENT; ANTIFOAMING_AGENT: Food Additives DIMETHYLPOLYSILOXANE 0â1.5 mg/kg bw The Committee withdrew the temporary ADI of 0â0.8 mg/kg body weight per day and re-established the ADI of 0â TRS 966-JECFA 74/27 FAS 60-JECFA 69/165 |
|---|---|
| GHS notification summary | 96.6% (86 / 89) |
| GHS notification summary | 96.6% (86 / 89) |
|---|---|
| Reported hazard statements | H225 (100%), H319 (100%), H335 (100%), H336 (100%) |
This chemical does not meet GHS hazard criteria for 96.6% (86 of 89) of all reports.
Reported as not meeting GHS hazard criteria by 86 of 89 companies (only 3.4% companies provided GHS information). For more detailed information, please visit ECHA C&L website.
POLYDIMETHYLSILOXANE · CAS 8050-81-5 · C6H18O4Si3. UNII SIMETICONE.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
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