Podophyllotoxin (CAS 518-28-5) — formula C22H22O8, molecular weight 414.4; category organic chemicals.
| CAS Number | 518-28-5 |
|---|---|
| Molecular Formula | C22H22O8 |
| Molecular Weight | 414.4 |
| Melting Point | 228 |
| LogP | 1.5 |
| Applications | Uses: Used in the treatment of warts and corns, [INCHEM], Antiviral, For treatment of external genital warts (<i>Condyloma acuminatum<, i>)., Methods of Manufacturing: Found in the rhizomes of North American Podophyllum peltatum L., Podophyllaceae, Podophyllin is a complex mixture of crystalline compounds derived from the mayapple plant. The active agent derived from this plant product, is, podophyllotoxin., Formulations, Preparations: Topical: Gel: 0.5%, Condylox, (Watson), Solution: 0.5%, Condylox (with alcohol 95% lactic acid and sodium lactate), (Watson)., General Manufacturing Information: Precursor of antineoplastics etoposide, teniposide. |
| Category | Organic Chemicals |
Documented applications: Uses: Used in the treatment of warts and corns, [INCHEM], Antiviral, For treatment of external genital warts (<i>Condyloma acuminatum<, i>)., Methods of Manufacturing: Found in the rhizomes of North American Podophyllum peltatum L., Podophyllaceae, Podophyllin is a complex mixture of crystalline compounds derived from the mayapple plant. The active agent derived from this plant product, is, podophyllotoxin., Formulations, Preparations: Topical: Gel: 0.5%, Condylox, (Watson), Solution: 0.5%, Condylox (with alcohol 95% lactic acid and sodium lactate), (Watson)., General Manufacturing Information: Precursor of antineoplastics etoposide, teniposide..
Podophyllotoxin is a carbon-based organic compound with CAS registry number 518-28-5 and molecular formula C22H22O8 (molecular weight 414.4), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 518-28-5
Its molecular formula C22H22O8 comprises 22 C, 22 H, 8 O atoms.
Also known as: Podophyllotoxin · 鬼臼毒素
Category: organic chemicals
The CAS registry number of Podophyllotoxin is 518-28-5.
Molecular formula C22H22O8, molecular weight 414.4.
It is also registered under: Podophyllotoxin, 鬼臼毒素.
Recorded applications: Uses: Used in the treatment of warts and corns, [INCHEM], Antiviral, For treatment of external genital warts (<i>Condyloma acuminatum<, i>)., Methods of Manufacturing: Found in the rhizomes of North American Podophyllum peltatum L., Podophyllaceae, Podophyllin is a complex mixture of crystalline compounds derived from the mayapple plant. The active agent derived from this plant product, is, podophyllotoxin., Formulations, Preparations: Topical: Gel: 0.5%, Condylox, (Watson), Solution: 0.5%, Condylox (with alcohol 95% lactic acid and sodium lactate), (Watson)., General Manufacturing Information: Precursor of antineoplastics etoposide, teniposide..
Category: Organic Chemicals.
Independent reference data for Podophyllotoxin (CAS 518-28-5), compiled from public chemistry databases.
| CAS Registry Number | 518-28-5 |
|---|---|
| PubChem CID | 10607 |
| Molecular formula | C22H22O8 |
| IUPAC name | (5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one |
| UNII (FDA) | L36H50F353 |
| Molecular Weight | 414.4 |
|---|---|
| XLogP3 | 2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 4 |
| Exact Mass | 414.13146766 |
| Monoisotopic Mass | 414.13146766 |
| Topological Polar Surface Area | 92.7 |
| Heavy Atom Count | 30 |
| Melting Point | 228 |
|---|---|
| Melting Point | 114-118 °C |
| Melting Point | 183 °C |
| Melting Point | MP: 114-118 °C (effervescence) |
| Melting Point | 228 °C |
| Solubility | 100 |
| Solubility | 1.14e-01 g/L |
| LogP | 1.5 |
| LogP | log Kow = 2.01 |
podophyllotoxin; Podofilox; 518-28-5; Condylox; (-)-Podophyllotoxin; Podophyllinic acid lactone; Podophyllotoxin 7; Wartec; Warticon; Podofilm; DTXSID3045645; NSC-24818; L36H50F353; DTXCID1025645; CHEBI:50305; 9-Hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5ah)-one
| GHS notification summary | 2.2% (1 / 46) |
|---|
| GHS notification summary | 2.2% (1 / 46) |
|---|---|
| Reported hazard statements | H301 (93.5%), H310 (95.7%), H315 (97.8%), H319 (97.8%), H335 (95.7%) |
This chemical does not meet GHS hazard criteria for 2.2% (1 of 46) of reports.
H301 (93.5%): Toxic if swallowed [Danger Acute toxicity, oral]
Podophyllotoxin · CAS 518-28-5 · C22H22O8. UNII L36H50F353. Melting Point: 228; Melting Point: 114-118 °C; Melting Point: 183 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 鬼臼毒素