(+-)-PGF2-alpha (CAS 23518-25-4) — formula C20H34O5, molecular weight 354.5; category organic chemicals.
| CAS Number | 23518-25-4 |
|---|---|
| Molecular Formula | C20H34O5 |
| Molecular Weight | 354.5 |
| Melting Point | 25-35 °C |
| LogP | 2.72 |
| Applications | Uses: MEDICATION (VET), MEDICATION, Methods of Manufacturing: ...SYNTH OF NATURAL PROSTAGLANDIN F2ALPHA: SCHNEIDER, MURRAY, J ORG CHEM 38, 397 (1973)., Formulations, Preparations: ...SOLN CONTAINING EQUIV OF 5 MG OF PROSTAGLANDIN F2ALPHA PER MILLILITER, IT IS AVAIL IN 4- & 8-ML AMPULS FOR INTRA-AMNIOTIC ADMIN TO INDUCE ABORTION., General Manufacturing Information: ...20-CARBON UNSATURATED CARBOXYLIC ACIDS WITH CYCLOPENTANE RING. ...KINSHIP WITH ESSENTIAL FATTY ACIDS... MAIN CLASSES--E, F, A, B, C, & D-DISTINGUISHED BY CONSTITUENTS OF...RING. ...SUBDIVIDED...WITH NUMBER OF DOUBLE BONDS IN SIDE CHAINS. ...INDICATED BY SUBSCRIPT...REFLECTS FATTY ACID PRECURSOR., PROSTAGLANDINS, PROSTAGLANDINS OF E & FALPHA SERIES ARE SOMETIMES REFERRED TO AS "PRIMARY PROSTAGLANDINS". ...MOST ABUNDANT (ESP E2 & F2ALPHA)..., IN VIVO MOST CELLS SEEM CAPABLE OF SYNTHESIZING PROSTAGLANDINS FROM ESSENTIAL FATTY ACID PRECURSORS. ...BELIEVED THAT ENDOGENOUS BIOSYNTHESIS, IN ABSENCE OF ADDED PRECURSOR ACID, DEPENDS ON PHOSPHOLIPASE-CATALYZED RELEASE OF PRECURSOR ACID FROM CELLULAR PHOSPHOLIPID STORES., SYNTH OF PRIMARY PROSTAGLANDINS...BY COMPLEX OF MICROSOMAL ENZYMES REFERRED TO AS "PROSTAGLANDIN SYNTHETASE." INITIAL EVENTS...RESULT IN OXYGENATION & CYCLIZATION OF UNESTERIFIED PRECURSOR ACID TO FORM CYCLIC PEROXIDE DERIV. ...ENDOPEROXIDE IS...REDUCED, YIELDING PGFALPHA COMPD., MOST PROLIFIC SOURCE OF NATURAL PROSTAGLANDINS IS MARINE ORGANISM CALLED GORGONIAN SEA WHIP, WHICH OCCURS...IN CORAL REEFS, ESP IN CARIBBEAN AREA. HARVESTING OF THESE HAS MADE PRODN...MUCH LESS EXPENSIVE. INTERMEDIATES & CHEM ANALOGS DERIVED FROM THIS NATURAL SOURCE...SYNTONS. |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION (VET), MEDICATION, Methods of Manufacturing: ...SYNTH OF NATURAL PROSTAGLANDIN F2ALPHA: SCHNEIDER, MURRAY, J ORG CHEM 38, 397 (1973)., Formulations, Preparations: ...SOLN CONTAINING EQUIV OF 5 MG OF PROSTAGLANDIN F2ALPHA PER MILLILITER, IT IS AVAIL IN 4- & 8-ML AMPULS FOR INTRA-AMNIOTIC ADMIN TO INDUCE ABORTION., General Manufacturing Information: ...20-CARBON UNSATURATED CARBOXYLIC ACIDS WITH CYCLOPENTANE RING. ...KINSHIP WITH ESSENTIAL FATTY ACIDS... MAIN CLASSES--E, F, A, B, C, & D-DISTINGUISHED BY CONSTITUENTS OF...RING. ...SUBDIVIDED...WITH NUMBER OF DOUBLE BONDS IN SIDE CHAINS. ...INDICATED BY SUBSCRIPT...REFLECTS FATTY ACID PRECURSOR., PROSTAGLANDINS, PROSTAGLANDINS OF E & FALPHA SERIES ARE SOMETIMES REFERRED TO AS "PRIMARY PROSTAGLANDINS". ...MOST ABUNDANT (ESP E2 & F2ALPHA)..., IN VIVO MOST CELLS SEEM CAPABLE OF SYNTHESIZING PROSTAGLANDINS FROM ESSENTIAL FATTY ACID PRECURSORS. ...BELIEVED THAT ENDOGENOUS BIOSYNTHESIS, IN ABSENCE OF ADDED PRECURSOR ACID, DEPENDS ON PHOSPHOLIPASE-CATALYZED RELEASE OF PRECURSOR ACID FROM CELLULAR PHOSPHOLIPID STORES., SYNTH OF PRIMARY PROSTAGLANDINS...BY COMPLEX OF MICROSOMAL ENZYMES REFERRED TO AS "PROSTAGLANDIN SYNTHETASE." INITIAL EVENTS...RESULT IN OXYGENATION & CYCLIZATION OF UNESTERIFIED PRECURSOR ACID TO FORM CYCLIC PEROXIDE DERIV. ...ENDOPEROXIDE IS...REDUCED, YIELDING PGFALPHA COMPD., MOST PROLIFIC SOURCE OF NATURAL PROSTAGLANDINS IS MARINE ORGANISM CALLED GORGONIAN SEA WHIP, WHICH OCCURS...IN CORAL REEFS, ESP IN CARIBBEAN AREA. HARVESTING OF THESE HAS MADE PRODN...MUCH LESS EXPENSIVE. INTERMEDIATES & CHEM ANALOGS DERIVED FROM THIS NATURAL SOURCE...SYNTONS..
(+-)-PGF2-alpha is a carbon-based organic compound with CAS registry number 23518-25-4 and molecular formula C20H34O5 (molecular weight 354.5), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 23518-25-4
Its molecular formula C20H34O5 comprises 20 C, 34 H, 5 O atoms.
Also known as: (+-)-PGF2-alpha · 人前列腺素F2(PGF2)Elisa试剂盒
Category: organic chemicals
The CAS registry number of (+-)-PGF2-alpha is 23518-25-4.
Molecular formula C20H34O5, molecular weight 354.5.
It is also registered under: (+-)-PGF2-alpha, 人前列腺素F2(PGF2)Elisa试剂盒.
Recorded applications: Uses: MEDICATION (VET), MEDICATION, Methods of Manufacturing: ...SYNTH OF NATURAL PROSTAGLANDIN F2ALPHA: SCHNEIDER, MURRAY, J ORG CHEM 38, 397 (1973)., Formulations, Preparations: ...SOLN CONTAINING EQUIV OF 5 MG OF PROSTAGLANDIN F2ALPHA PER MILLILITER, IT IS AVAIL IN 4- & 8-ML AMPULS FOR INTRA-AMNIOTIC ADMIN TO INDUCE ABORTION., General Manufacturing Information: ...20-CARBON UNSATURATED CARBOXYLIC ACIDS WITH CYCLOPENTANE RING. ...KINSHIP WITH ESSENTIAL FATTY ACIDS... MAIN CLASSES--E, F, A, B, C, & D-DISTINGUISHED BY CONSTITUENTS OF...RING. ...SUBDIVIDED...WITH NUMBER OF DOUBLE BONDS IN SIDE CHAINS. ...INDICATED BY SUBSCRIPT...REFLECTS FATTY ACID PRECURSOR., PROSTAGLANDINS, PROSTAGLANDINS OF E & FALPHA SERIES ARE SOMETIMES REFERRED TO AS "PRIMARY PROSTAGLANDINS". ...MOST ABUNDANT (ESP E2 & F2ALPHA)..., IN VIVO MOST CELLS SEEM CAPABLE OF SYNTHESIZING PROSTAGLANDINS FROM ESSENTIAL FATTY ACID PRECURSORS. ...BELIEVED THAT ENDOGENOUS BIOSYNTHESIS, IN ABSENCE OF ADDED PRECURSOR ACID, DEPENDS ON PHOSPHOLIPASE-CATALYZED RELEASE OF PRECURSOR ACID FROM CELLULAR PHOSPHOLIPID STORES., SYNTH OF PRIMARY PROSTAGLANDINS...BY COMPLEX OF MICROSOMAL ENZYMES REFERRED TO AS "PROSTAGLANDIN SYNTHETASE." INITIAL EVENTS...RESULT IN OXYGENATION & CYCLIZATION OF UNESTERIFIED PRECURSOR ACID TO FORM CYCLIC PEROXIDE DERIV. ...ENDOPEROXIDE IS...REDUCED, YIELDING PGFALPHA COMPD., MOST PROLIFIC SOURCE OF NATURAL PROSTAGLANDINS IS MARINE ORGANISM CALLED GORGONIAN SEA WHIP, WHICH OCCURS...IN CORAL REEFS, ESP IN CARIBBEAN AREA. HARVESTING OF THESE HAS MADE PRODN...MUCH LESS EXPENSIVE. INTERMEDIATES & CHEM ANALOGS DERIVED FROM THIS NATURAL SOURCE...SYNTONS..
Category: Organic Chemicals.
Independent reference data for (+-)-PGF2-alpha (CAS 23518-25-4), compiled from public chemistry databases.
| CAS 号 | 23518-25-4 |
|---|---|
| PubChem CID | 5280363 |
| 分子式 | C20H34O5 |
| IUPAC 名称 | (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid |
| UNII（FDA） | B7IN85G1HY |
| Molecular Weight | 354.5 |
|---|---|
| XLogP3 | 2.7 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 12 |
| Exact Mass | 354.24062418 |
| Monoisotopic Mass | 354.24062418 |
| Topological Polar Surface Area | 98 |
| Heavy Atom Count | 25 |
| Melting Point | 25-35 °C |
|---|---|
| LogP | 2.72 |
| Collision Cross Section | 194.1 Ų [M-H]- |
| Collision Cross Section | 204.4 Ų [M+Na]+ |
dinoprost; prostaglandin F2alpha; PGF2alpha; Prostaglandin F2a; amoglandin; Enzaprost; panacelan; Dinoprosta; Protamodin; Prostaglandin F2-alpha; l-PGF2-alpha; PGF2a; PGF-2alpha; PGF2-alpha; Dinoprostum; Prosmon
| 已通报的危害声明 | H302 (100%), H319 (89.7%), H360 (97.4%), H370 (89.7%), H372 (89.7%) |
|---|
人前列腺素F2(PGF2)Elisa试剂盒 · CAS 23518-25-4 · C20H34O5. UNII B7IN85G1HY. Melting Point: 25-35 °C; LogP: 2.72; Collision Cross Section: 194.1 Ų [M-H]-.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 人前列腺素F2(PGF2)Elisa试剂盒