p-Anisaldehyde (CAS 123-11-5) — formula C8H8O2, molecular weight 136.05 g/mol.
| CAS Number | 123-11-5 |
|---|---|
| Molecular Formula | C8H8O2 |
| Molecular Weight | 136.05 g/mol |
| Melting Point | 0 °C |
| Boiling Point | 255 °C |
| LogP | 1.8 |
| Applications | Uses: Metabolite of Lentinus lepidus (oderiforous fungus), Polyporus benzoinus (wood rotting fungus), and Daldalea juniperina, [Merck Index] Found in various essential oils and extracts, Used to make insect attractants (especially for cockroaches), Also used in electroplating and in fragrances and flavors, [HSDB], Electroplating [Category: Plate], Perfumery and toilet soaps, ... also used in organic syntheses., p-Anisaldehyde is an intermediate in many industrial processes., Reported uses (ppm):, Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#4114], Intermediate for antihistamines, electroplating., Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Industry Uses: Not Known or Reasonably Ascertainable, Fragrance, Other, Flavoring and nutrient, Consumer Uses: Not Known or Reasonably Ascertainable, Household Products: Information on 136 consumer products that contain Anisaldehyde in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Inside the Home, • Personal Care, Methods of Manufacturing: By methylation and oxidation of p-cresol and also by oxidation of anethole., OXIDATION OF ANETHOLE WITH CHROMIC ACID, METHYLATION OF P-CRESOL TO P-CRESYL METHYL ETHER, FOLLOWED BY OXIDATION WITH MANGANESE DIOXIDE, IFRA Fragrance Standards: p-Methoxybenzaldehyde, p-Methoxybenzaldehyde, Anisaldehyde, p-Anisaldehyde, Anisic aldehyde, Anisyl aldehyde, Benzaldehyde, 4-methoxy, 4-Methoxybenzaldehyde, Aubepine P Cresol (commercial name), Aubepine liquid (commercial name), IFRA_STD_054.pdf, 51, IFRA 51st Amendment - Guidance for the use of IFRA Standards, Restriction: This material should be used only in the limited quantity as stated in the Standard, DERMAL SENSITIZATION AND SYSTEMIC TOXICITY, Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards., Restriction Limits in the Finished Product (%): 0.23 [Products applied to the lips], 080 [Products applied to the axillae], 0.14 [Products applied to the face, body using fingertips], 1.4 [Products related to fine fragrances], 0.38 [Products applied to the body using the hands (palms), primarily leave-on (Body lotion)], 0.093 [Products applied to the face using the hands (palms), primarily leave-on (Face moisturizer)], 0.14 [Products applied to the hands using the hands (palms), primarily leave-on (Hand cream)], 0.031 [Products applied to babies using the hands (palms), primarily leave-on (Baby cream, oil, talc)], 0.047 [Products with oral and lip exposure], 0.14 [Rinse-off products applied to the hair with some hand contact], 0.14 [Leave-on products applied to the hair with some hand contact], 0.031 [Products with significant anogenital exposure (tampon)], 0.42 [Products with body and hand exposure, primarily rinse off], 0.19 [Household care products with mostly hand contact (excluding aerosol, spray products)], 1.1 [Household care products with mostly hand contact (household aerosol, 0.031 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure], 0.031 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure], 31 [Other air care products not intended for direct skin contact, minimal or insignificant transfer to skin], Formulations, Preparations: Liquid and crystals, the latter being the disulfite compound., U.S. Production: 2023: 8, 500, 000 - <10, 000, 000 lb, 2022: 10, 000 - <25, 2021: 10, 2020: 10, (1972) 4.8X10+8 GRAMS, Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: p-Anisaldehyde:, Table: National Aggregate Production Volume (pounds) [Table#4113], U.S. Imports: (1972) No Data, (1975) No Data, U.S. Exports: (1972) No Data, General Manufacturing Information: Soap, Cleaning Compound, and Toilet Preparation Manufacturing, Food, beverage, and tobacco product manufacturing, All Other Basic Organic Chemical Manufacturing, Plastics Material and Resin Manufacturing, All Other Chemical Product and Preparation Manufacturing, 4-methoxy-: ACTIVE |
Documented applications: Uses: Metabolite of Lentinus lepidus (oderiforous fungus), Polyporus benzoinus (wood rotting fungus), and Daldalea juniperina, [Merck Index] Found in various essential oils and extracts, Used to make insect attractants (especially for cockroaches), Also used in electroplating and in fragrances and flavors, [HSDB], Electroplating [Category: Plate], Perfumery and toilet soaps, ... also used in organic syntheses., p-Anisaldehyde is an intermediate in many industrial processes., Reported uses (ppm):, Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#4114], Intermediate for antihistamines, electroplating., Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Industry Uses: Not Known or Reasonably Ascertainable, Fragrance, Other, Flavoring and nutrient, Consumer Uses: Not Known or Reasonably Ascertainable, Household Products: Information on 136 consumer products that contain Anisaldehyde in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Inside the Home, • Personal Care, Methods of Manufacturing: By methylation and oxidation of p-cresol and also by oxidation of anethole., OXIDATION OF ANETHOLE WITH CHROMIC ACID, METHYLATION OF P-CRESOL TO P-CRESYL METHYL ETHER, FOLLOWED BY OXIDATION WITH MANGANESE DIOXIDE, IFRA Fragrance Standards: p-Methoxybenzaldehyde, p-Methoxybenzaldehyde, Anisaldehyde, p-Anisaldehyde, Anisic aldehyde, Anisyl aldehyde, Benzaldehyde, 4-methoxy, 4-Methoxybenzaldehyde, Aubepine P Cresol (commercial name), Aubepine liquid (commercial name), IFRA_STD_054.pdf, 51, IFRA 51st Amendment - Guidance for the use of IFRA Standards, Restriction: This material should be used only in the limited quantity as stated in the Standard, DERMAL SENSITIZATION AND SYSTEMIC TOXICITY, Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards., Restriction Limits in the Finished Product (%): 0.23 [Products applied to the lips], 080 [Products applied to the axillae], 0.14 [Products applied to the face, body using fingertips], 1.4 [Products related to fine fragrances], 0.38 [Products applied to the body using the hands (palms), primarily leave-on (Body lotion)], 0.093 [Products applied to the face using the hands (palms), primarily leave-on (Face moisturizer)], 0.14 [Products applied to the hands using the hands (palms), primarily leave-on (Hand cream)], 0.031 [Products applied to babies using the hands (palms), primarily leave-on (Baby cream, oil, talc)], 0.047 [Products with oral and lip exposure], 0.14 [Rinse-off products applied to the hair with some hand contact], 0.14 [Leave-on products applied to the hair with some hand contact], 0.031 [Products with significant anogenital exposure (tampon)], 0.42 [Products with body and hand exposure, primarily rinse off], 0.19 [Household care products with mostly hand contact (excluding aerosol, spray products)], 1.1 [Household care products with mostly hand contact (household aerosol, 0.031 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure], 0.031 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure], 31 [Other air care products not intended for direct skin contact, minimal or insignificant transfer to skin], Formulations, Preparations: Liquid and crystals, the latter being the disulfite compound., U.S. Production: 2023: 8, 500, 000 - <10, 000, 000 lb, 2022: 10, 000 - <25, 2021: 10, 2020: 10, (1972) 4.8X10+8 GRAMS, Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: p-Anisaldehyde:, Table: National Aggregate Production Volume (pounds) [Table#4113], U.S. Imports: (1972) No Data, (1975) No Data, U.S. Exports: (1972) No Data, General Manufacturing Information: Soap, Cleaning Compound, and Toilet Preparation Manufacturing, Food, beverage, and tobacco product manufacturing, All Other Basic Organic Chemical Manufacturing, Plastics Material and Resin Manufacturing, All Other Chemical Product and Preparation Manufacturing, 4-methoxy-: ACTIVE.
p-Anisaldehyde is a chemical compound with CAS registry number 123-11-5 and molecular formula C8H8O2 (molecular weight 136.05 g/mol).
CAS number: 123-11-5
Its molecular formula C8H8O2 comprises 8 C, 8 H, 2 O atoms.
Also known as: p-Anisaldehyde · Anisaldehyde
The CAS registry number of p-Anisaldehyde is 123-11-5.
Molecular formula C8H8O2, molecular weight 136.05 g/mol.
It is also registered under: p-Anisaldehyde, Anisaldehyde.
Recorded applications: Uses: Metabolite of Lentinus lepidus (oderiforous fungus), Polyporus benzoinus (wood rotting fungus), and Daldalea juniperina, [Merck Index] Found in various essential oils and extracts, Used to make insect attractants (especially for cockroaches), Also used in electroplating and in fragrances and flavors, [HSDB], Electroplating [Category: Plate], Perfumery and toilet soaps, ... also used in organic syntheses., p-Anisaldehyde is an intermediate in many industrial processes., Reported uses (ppm):, Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#4114], Intermediate for antihistamines, electroplating., Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Industry Uses: Not Known or Reasonably Ascertainable, Fragrance, Other, Flavoring and nutrient, Consumer Uses: Not Known or Reasonably Ascertainable, Household Products: Information on 136 consumer products that contain Anisaldehyde in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Inside the Home, • Personal Care, Methods of Manufacturing: By methylation and oxidation of p-cresol and also by oxidation of anethole., OXIDATION OF ANETHOLE WITH CHROMIC ACID, METHYLATION OF P-CRESOL TO P-CRESYL METHYL ETHER, FOLLOWED BY OXIDATION WITH MANGANESE DIOXIDE, IFRA Fragrance Standards: p-Methoxybenzaldehyde, p-Methoxybenzaldehyde, Anisaldehyde, p-Anisaldehyde, Anisic aldehyde, Anisyl aldehyde, Benzaldehyde, 4-methoxy, 4-Methoxybenzaldehyde, Aubepine P Cresol (commercial name), Aubepine liquid (commercial name), IFRA_STD_054.pdf, 51, IFRA 51st Amendment - Guidance for the use of IFRA Standards, Restriction: This material should be used only in the limited quantity as stated in the Standard, DERMAL SENSITIZATION AND SYSTEMIC TOXICITY, Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards., Restriction Limits in the Finished Product (%): 0.23 [Products applied to the lips], 080 [Products applied to the axillae], 0.14 [Products applied to the face, body using fingertips], 1.4 [Products related to fine fragrances], 0.38 [Products applied to the body using the hands (palms), primarily leave-on (Body lotion)], 0.093 [Products applied to the face using the hands (palms), primarily leave-on (Face moisturizer)], 0.14 [Products applied to the hands using the hands (palms), primarily leave-on (Hand cream)], 0.031 [Products applied to babies using the hands (palms), primarily leave-on (Baby cream, oil, talc)], 0.047 [Products with oral and lip exposure], 0.14 [Rinse-off products applied to the hair with some hand contact], 0.14 [Leave-on products applied to the hair with some hand contact], 0.031 [Products with significant anogenital exposure (tampon)], 0.42 [Products with body and hand exposure, primarily rinse off], 0.19 [Household care products with mostly hand contact (excluding aerosol, spray products)], 1.1 [Household care products with mostly hand contact (household aerosol, 0.031 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure], 0.031 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure], 31 [Other air care products not intended for direct skin contact, minimal or insignificant transfer to skin], Formulations, Preparations: Liquid and crystals, the latter being the disulfite compound., U.S. Production: 2023: 8, 500, 000 - <10, 000, 000 lb, 2022: 10, 000 - <25, 2021: 10, 2020: 10, (1972) 4.8X10+8 GRAMS, Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: p-Anisaldehyde:, Table: National Aggregate Production Volume (pounds) [Table#4113], U.S. Imports: (1972) No Data, (1975) No Data, U.S. Exports: (1972) No Data, General Manufacturing Information: Soap, Cleaning Compound, and Toilet Preparation Manufacturing, Food, beverage, and tobacco product manufacturing, All Other Basic Organic Chemical Manufacturing, Plastics Material and Resin Manufacturing, All Other Chemical Product and Preparation Manufacturing, 4-methoxy-: ACTIVE.
Independent reference data for p-Anisaldehyde (CAS 123-11-5), compiled from public chemistry databases.
| CAS Registry Number | 123-11-5 |
|---|---|
| PubChem CID | 31244 |
| Molecular formula | C8H8O2 |
| Molecular weight | 136.05 g/mol |
| IUPAC name | 4-methoxybenzaldehyde |
| InChIKey | ZRSNZINYAWTAHE-UHFFFAOYSA-N |
| UNII (FDA) | 9PA5V6656V |
| ChEBI ID | CHEBI:28235 |
| FEMA number | 2670 |
| JECFA number | 878 |
| Molecular Weight | 136.15 |
|---|---|
| XLogP3 | 1.8 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 136.052429494 |
| Monoisotopic Mass | 136.052429494 |
| Topological Polar Surface Area | 26.3 |
| Heavy Atom Count | 10 |
| Boiling Point | 255 °C |
|---|---|
| Boiling Point | 248.00 to 249.00 °C. @ 760.00 mm Hg |
| Boiling Point | 248 °C |
| Melting Point | 0 °C |
| Flash Point | 116 °C (241 °F) - closed cup |
| Solubility | In water, 4.29X10+3 mg/L at 25 °C |
| Solubility | 4.29 mg/mL at 25 °C |
| Density | 1.1191 g/cu cm at 15 °C |
| Density | 1.115-1.123 |
| Vapor Density | 4.7 (Air = 1) |
4-Methoxybenzaldehyde; 123-11-5; P-ANISALDEHYDE; Anisaldehyde; p-Methoxybenzaldehyde; 4-Anisaldehyde; Benzaldehyde, 4-methoxy-; Crategine; p-Formylanisole; Obepin; p-Anisic aldehyde; para-anisaldehyde; 4-Methoxy-benzaldehyde; FEMA No. 2670; DTXSID2026997; 9PA5V6656V
| Regulatory & Food Contact | EU Flavoring substances FDA Substance added to food: FLAVORING AGENT OR ADJUVANT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent Almond, Anise, Mint No safety concern at current levels of intake when used as a flavouring agent |
|---|---|
| GHS notification summary | 57% (2268 / 3980) |
| GHS notification summary | 57% (2268 / 3980) |
|---|---|
| Reported hazard statements | H302 (40.1%), H361 |
This chemical does not meet GHS hazard criteria for 57% (2268 of 3980) of all reports.
H302 (40.1%): Harmful if swallowed [Warning Acute toxicity, oral]
p-Anisaldehyde is identified by CAS 123-11-5, molecular formula C8H8O2 and molecular weight 136.05 g/mol. UNII 9PA5V6656V; ChEBI 28235; InChIKey ZRSNZINYAWTAHE-UHFFFAOYSA-N. Boiling Point: 255 °C; Boiling Point: 248.00 to 249.00 °C. @ 760.00 mm Hg; Boiling Point: 248 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
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