盐酸昂丹司琼二水合物

Description

Ondansetron hydrochloride dihydrate · CAS 103639-04-9 · C18H24ClN3O3. UNII NMH84OZK2B.

Identification

CAS Registry Number	103639-04-9
PubChem CID	59774
Molecular formula	C18H24ClN3O3
IUPAC name	9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one;dihydrate;hydrochloride
UNII (FDA)	NMH84OZK2B

Computed Descriptors

Molecular Weight	365.9
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	365.1506193
Monoisotopic Mass	365.1506193
Topological Polar Surface Area	41.8
Heavy Atom Count	25
Formal Charge	0
Complexity	440

GHS Hazard Classification

Reported hazard statements	H301 (100%), H318 (84.6%), H319 (11.1%), H400 (84.6%), H410 (82.9%)

Documented Uses

• For the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, postoperation, and radiation. Also used for the treatment of postoperative nausea and vomiting.
• Breast Feeding; Lactation; Milk, Human; Antiemetics; Gastrointestinal Agents; Serotonin Antagonists; Serotonin 5-HT3 Receptor Antagonists
• Ondansetron hydrochloride is approved to prevent:
• • Nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It is used in adults and children.
• Ondansetron hydrochloride is also being studied in the treatment of other conditions.
• Drugs used to prevent NAUSEA or VOMITING.

Synonyms

Zofran; RefChem:934563; Ondansetron hydrochloride dihydrate; 103639-04-9; Ondansetron hydrochloride hydrate; Setrodon; DTXSID9048857; 9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one;dihydrate;hydrochloride; GR-38032F; MFCD00374371; CHEBI:7774; DTXCID6028783; Ondansetron (hydrochloride dihydrate); 9-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride dihydrate; KS-1091; ONDANSETRON HYDROCHLORIDE [MART.]

Frequently Asked Questions

What are the CAS number and molecular formula of Ondansetron hydrochloride dihydrate?

CAS 103639-04-9; molecular formula C18H24ClN3O3; molecular weight — g/mol.

What other names is Ondansetron hydrochloride dihydrate known by?

Zofran, RefChem:934563, Ondansetron hydrochloride dihydrate, 103639-04-9, Ondansetron hydrochloride hydrate, Setrodon.

Is Ondansetron hydrochloride dihydrate classified as hazardous?

Hazard statements reported: H301, H318, H319, H400, H410.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.