Octamethyl cyclotetrasiloxane (CAS 556-67-2) — formula C8H24O4Si4, molecular weight 296.61; category organic chemicals.
| CAS Number | 556-67-2 |
|---|---|
| Molecular Formula | C8H24O4Si4 |
| Molecular Weight | 296.61 |
| Melting Point | 17.5 °C |
| Boiling Point | 175 °C |
| Applications | Uses: Used to make methyl silicon oils, silicone fluids, and elastomers, Also used in a variety of applications including fermentation processes, instant coffee production, paper coatings and sizing, diet soft drinks, waste yeast tanks, food washing solutions, adhesives, textiles, de-asphalting, boiler treatments, detergents, cleaning solutions, cosmetic products, and polishes, [HSDB], Pulp and Paper Processing [Category: Industry], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Working with Glues and Adhesives [Category: Other], Preparation of methyl silicon oils., Field of application: Fuel additives, cleaning, washing agents, impregnation materials, binding agents, surface treatment, construction materials, paints, lacquers and varnishes, fillers, reprographic agents, process regulators, anti-set-off, anti adhesive agents., From table, Octamethylcyclotetrasiloxane has widespread use in a variety of applications including fermentation processes, deasphalting, and polishes., Used as a precursor in the production of polydimethylsiloxane polymers, which are widely used in various industrial and consumer applications, topical pharmaceutical formulations and as breast implants, the polymers contain some residual monomers. Used in cosmetics as an antistatic, emollient, humectant, solvent, viscosity controller, and hair conditioner. Depending on the product type, the concentration of D4 (octamethylcyclotetrasiloxane) in formulations varies between 0.1 and 54%, it is common to use a blend of cyclosiloxanes D4, D5 and D6 in cosmetic products. Cyclosiloxane blends containing D4, D5 and D6 are used in the formulation of various types of hair care and skin care products as well as in antiperspirants, deodorants. Certain food products are processed using silicone antifoam containing octamethyltetracyclosiloxane., For more Uses (Complete) data for OCTAMETHYLCYCLOTETRASILOXANE (8 total), please visit the HSDB record page., Use Classification: Cosmetics -> Hair conditioning, Solvent, Humectant, Antistatic, Viscosity controlling, Emollient, Industry Uses: Solvent, Monomers, Viscosity modifiers, Diluent, Not Known or Reasonably Ascertainable, Surface modifier, Terminator, Blocker, Intermediate, Adhesion, cohesion promoter, Consumer Uses: Monomers, Household Products: Cosmetics product ingredient: Octamethylcyclotetrasiloxane (D4) (Cyclotetrasiloxane), Reason for Listing:, - Included in the European Union candidate list of Substances of Very High Concern in accordance with Article 59 of Regulation (EC) 1907, 2006 on the basis of Article 57(d), Article 57(e), or Article 57(f) for persistent, bioaccumulative and toxic, or very persistent and very bioaccumulative properties, - Identified as Persistent, Bioaccumulative, and Inherently Toxic to the environment by the Canadian Environmental Protection Act Environmental Registry Domestic Substances List, - Identified under the California Environmental Contaminant Biomonitoring Program, Potential Health Impacts: Bioaccumulation, Environmental Persistence, and Reproductive Toxicity, Product count: 17, Information on 133 consumer products that contain Octamethylcydotetrasiloxane in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Hobby, Craft, • Home Maintenance, • Inside the Home, • Personal Care, Methods of Manufacturing: Isolated from hydrolysis product of dimethyldichlorosilane., Acid hydrolysis of dimethyldichlorosilane gives a hydrolysate mixture of linear and cyclic polysiloxanes with octamethylcyclotetrasiloxane as the main cyclic component., Formulations, Preparations: The combination of D4, octamethylcyclotetrasiloxane, with decamethylcyclopentasiloxane (D5) is commonly referred to as cyclomethicone which has a wide range of applications as a formulation aid in personal care products., U.S. Production: 2023: 250, 000, 000 - <400, 000 lb, 2022: 250, 2021: 250, 2020: 100, 000 - <500, (1977) At least 4.54x10+5 g (est.), (1986) >100 million-500 million pounds, (1990) >100 million-500 million pounds, (1994) >100 million-500 million pounds, For more U.S. Production (Complete) data for OCTAMETHYLCYCLOTETRASILOXANE (8 total), General Manufacturing Information: Miscellaneous Manufacturing, Other (requires additional information), All Other Basic Organic Chemical Manufacturing, Paint and Coating Manufacturing, Adhesive Manufacturing, All Other Chemical Product and Preparation Manufacturing, Soap, Cleaning Compound, and Toilet Preparation Manufacturing, Synthetic Rubber Manufacturing, Plastics Product Manufacturing, Utilities, All Other Basic Inorganic Chemical Manufacturing, Cyclotetrasiloxane, 2, 4, 6, 8, 8-octamethyl-: ACTIVE, In the preparation of silicone-coated membranes for use in blood oxygenators, plasma polymerization of octamethylcyclotetrasiloxane in celgard membrane showed better blood compatibility than silastic sheeting or glass., Octamethylcyclotetrasiloxane is used to replace isopropyl myristate, isopropyl palmitate, or other oily carriers used in deodorants or antiperspirants., In a study dated from September 2, 2004 the Danish EPA found octamethylcyclotetrasiloxane in creams and styling supplies at average concentrations of 0.3 and 0.8%. The study states that the materials would no longer be used in these products during the upcoming year., Cyclomethicone is a generic name for several cyclic dimethyl polysiloxane compounds ... it refers not only to octamethylcyclotetrasiloxane (D4), but also to cyclotrisiloxane (D3), cyclope |
| Category | Organic Chemicals |
Documented applications: Uses: Used to make methyl silicon oils, silicone fluids, and elastomers, Also used in a variety of applications including fermentation processes, instant coffee production, paper coatings and sizing, diet soft drinks, waste yeast tanks, food washing solutions, adhesives, textiles, de-asphalting, boiler treatments, detergents, cleaning solutions, cosmetic products, and polishes, [HSDB], Pulp and Paper Processing [Category: Industry], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Working with Glues and Adhesives [Category: Other], Preparation of methyl silicon oils., Field of application: Fuel additives, cleaning, washing agents, impregnation materials, binding agents, surface treatment, construction materials, paints, lacquers and varnishes, fillers, reprographic agents, process regulators, anti-set-off, anti adhesive agents., From table, Octamethylcyclotetrasiloxane has widespread use in a variety of applications including fermentation processes, deasphalting, and polishes., Used as a precursor in the production of polydimethylsiloxane polymers, which are widely used in various industrial and consumer applications, topical pharmaceutical formulations and as breast implants, the polymers contain some residual monomers. Used in cosmetics as an antistatic, emollient, humectant, solvent, viscosity controller, and hair conditioner. Depending on the product type, the concentration of D4 (octamethylcyclotetrasiloxane) in formulations varies between 0.1 and 54%, it is common to use a blend of cyclosiloxanes D4, D5 and D6 in cosmetic products. Cyclosiloxane blends containing D4, D5 and D6 are used in the formulation of various types of hair care and skin care products as well as in antiperspirants, deodorants. Certain food products are processed using silicone antifoam containing octamethyltetracyclosiloxane., For more Uses (Complete) data for OCTAMETHYLCYCLOTETRASILOXANE (8 total), please visit the HSDB record page., Use Classification: Cosmetics -> Hair conditioning, Solvent, Humectant, Antistatic, Viscosity controlling, Emollient, Industry Uses: Solvent, Monomers, Viscosity modifiers, Diluent, Not Known or Reasonably Ascertainable, Surface modifier, Terminator, Blocker, Intermediate, Adhesion, cohesion promoter, Consumer Uses: Monomers, Household Products: Cosmetics product ingredient: Octamethylcyclotetrasiloxane (D4) (Cyclotetrasiloxane), Reason for Listing:, - Included in the European Union candidate list of Substances of Very High Concern in accordance with Article 59 of Regulation (EC) 1907, 2006 on the basis of Article 57(d), Article 57(e), or Article 57(f) for persistent, bioaccumulative and toxic, or very persistent and very bioaccumulative properties, - Identified as Persistent, Bioaccumulative, and Inherently Toxic to the environment by the Canadian Environmental Protection Act Environmental Registry Domestic Substances List, - Identified under the California Environmental Contaminant Biomonitoring Program, Potential Health Impacts: Bioaccumulation, Environmental Persistence, and Reproductive Toxicity, Product count: 17, Information on 133 consumer products that contain Octamethylcydotetrasiloxane in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Hobby, Craft, • Home Maintenance, • Inside the Home, • Personal Care, Methods of Manufacturing: Isolated from hydrolysis product of dimethyldichlorosilane., Acid hydrolysis of dimethyldichlorosilane gives a hydrolysate mixture of linear and cyclic polysiloxanes with octamethylcyclotetrasiloxane as the main cyclic component., Formulations, Preparations: The combination of D4, octamethylcyclotetrasiloxane, with decamethylcyclopentasiloxane (D5) is commonly referred to as cyclomethicone which has a wide range of applications as a formulation aid in personal care products., U.S. Production: 2023: 250, 000, 000 - <400, 000 lb, 2022: 250, 2021: 250, 2020: 100, 000 - <500, (1977) At least 4.54x10+5 g (est.), (1986) >100 million-500 million pounds, (1990) >100 million-500 million pounds, (1994) >100 million-500 million pounds, For more U.S. Production (Complete) data for OCTAMETHYLCYCLOTETRASILOXANE (8 total), General Manufacturing Information: Miscellaneous Manufacturing, Other (requires additional information), All Other Basic Organic Chemical Manufacturing, Paint and Coating Manufacturing, Adhesive Manufacturing, All Other Chemical Product and Preparation Manufacturing, Soap, Cleaning Compound, and Toilet Preparation Manufacturing, Synthetic Rubber Manufacturing, Plastics Product Manufacturing, Utilities, All Other Basic Inorganic Chemical Manufacturing, Cyclotetrasiloxane, 2, 4, 6, 8, 8-octamethyl-: ACTIVE, In the preparation of silicone-coated membranes for use in blood oxygenators, plasma polymerization of octamethylcyclotetrasiloxane in celgard membrane showed better blood compatibility than silastic sheeting or glass., Octamethylcyclotetrasiloxane is used to replace isopropyl myristate, isopropyl palmitate, or other oily carriers used in deodorants or antiperspirants., In a study dated from September 2, 2004 the Danish EPA found octamethylcyclotetrasiloxane in creams and styling supplies at average concentrations of 0.3 and 0.8%. The study states that the materials would no longer be used in these products during the upcoming year., Cyclomethicone is a generic name for several cyclic dimethyl polysiloxane compounds ... it refers not only to octamethylcyclotetrasiloxane (D4), but also to cyclotrisiloxane (D3), cyclope.
Octamethyl cyclotetrasiloxane is a carbon-based organic compound with CAS registry number 556-67-2 and molecular formula C8H24O4Si4 (molecular weight 296.61), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 556-67-2
Its molecular formula C8H24O4Si4 comprises 8 C, 24 H, 4 O, 4 Si atoms.
Also known as: Octamethyl cyclotetrasiloxane · 八甲基环四硅氧烷
Category: organic chemicals
The CAS registry number of Octamethyl cyclotetrasiloxane is 556-67-2.
Molecular formula C8H24O4Si4, molecular weight 296.61.
It is also registered under: Octamethyl cyclotetrasiloxane, 八甲基环四硅氧烷.
Recorded applications: Uses: Used to make methyl silicon oils, silicone fluids, and elastomers, Also used in a variety of applications including fermentation processes, instant coffee production, paper coatings and sizing, diet soft drinks, waste yeast tanks, food washing solutions, adhesives, textiles, de-asphalting, boiler treatments, detergents, cleaning solutions, cosmetic products, and polishes, [HSDB], Pulp and Paper Processing [Category: Industry], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Working with Glues and Adhesives [Category: Other], Preparation of methyl silicon oils., Field of application: Fuel additives, cleaning, washing agents, impregnation materials, binding agents, surface treatment, construction materials, paints, lacquers and varnishes, fillers, reprographic agents, process regulators, anti-set-off, anti adhesive agents., From table, Octamethylcyclotetrasiloxane has widespread use in a variety of applications including fermentation processes, deasphalting, and polishes., Used as a precursor in the production of polydimethylsiloxane polymers, which are widely used in various industrial and consumer applications, topical pharmaceutical formulations and as breast implants, the polymers contain some residual monomers. Used in cosmetics as an antistatic, emollient, humectant, solvent, viscosity controller, and hair conditioner. Depending on the product type, the concentration of D4 (octamethylcyclotetrasiloxane) in formulations varies between 0.1 and 54%, it is common to use a blend of cyclosiloxanes D4, D5 and D6 in cosmetic products. Cyclosiloxane blends containing D4, D5 and D6 are used in the formulation of various types of hair care and skin care products as well as in antiperspirants, deodorants. Certain food products are processed using silicone antifoam containing octamethyltetracyclosiloxane., For more Uses (Complete) data for OCTAMETHYLCYCLOTETRASILOXANE (8 total), please visit the HSDB record page., Use Classification: Cosmetics -> Hair conditioning, Solvent, Humectant, Antistatic, Viscosity controlling, Emollient, Industry Uses: Solvent, Monomers, Viscosity modifiers, Diluent, Not Known or Reasonably Ascertainable, Surface modifier, Terminator, Blocker, Intermediate, Adhesion, cohesion promoter, Consumer Uses: Monomers, Household Products: Cosmetics product ingredient: Octamethylcyclotetrasiloxane (D4) (Cyclotetrasiloxane), Reason for Listing:, - Included in the European Union candidate list of Substances of Very High Concern in accordance with Article 59 of Regulation (EC) 1907, 2006 on the basis of Article 57(d), Article 57(e), or Article 57(f) for persistent, bioaccumulative and toxic, or very persistent and very bioaccumulative properties, - Identified as Persistent, Bioaccumulative, and Inherently Toxic to the environment by the Canadian Environmental Protection Act Environmental Registry Domestic Substances List, - Identified under the California Environmental Contaminant Biomonitoring Program, Potential Health Impacts: Bioaccumulation, Environmental Persistence, and Reproductive Toxicity, Product count: 17, Information on 133 consumer products that contain Octamethylcydotetrasiloxane in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Hobby, Craft, • Home Maintenance, • Inside the Home, • Personal Care, Methods of Manufacturing: Isolated from hydrolysis product of dimethyldichlorosilane., Acid hydrolysis of dimethyldichlorosilane gives a hydrolysate mixture of linear and cyclic polysiloxanes with octamethylcyclotetrasiloxane as the main cyclic component., Formulations, Preparations: The combination of D4, octamethylcyclotetrasiloxane, with decamethylcyclopentasiloxane (D5) is commonly referred to as cyclomethicone which has a wide range of applications as a formulation aid in personal care products., U.S. Production: 2023: 250, 000, 000 - <400, 000 lb, 2022: 250, 2021: 250, 2020: 100, 000 - <500, (1977) At least 4.54x10+5 g (est.), (1986) >100 million-500 million pounds, (1990) >100 million-500 million pounds, (1994) >100 million-500 million pounds, For more U.S. Production (Complete) data for OCTAMETHYLCYCLOTETRASILOXANE (8 total), General Manufacturing Information: Miscellaneous Manufacturing, Other (requires additional information), All Other Basic Organic Chemical Manufacturing, Paint and Coating Manufacturing, Adhesive Manufacturing, All Other Chemical Product and Preparation Manufacturing, Soap, Cleaning Compound, and Toilet Preparation Manufacturing, Synthetic Rubber Manufacturing, Plastics Product Manufacturing, Utilities, All Other Basic Inorganic Chemical Manufacturing, Cyclotetrasiloxane, 2, 4, 6, 8, 8-octamethyl-: ACTIVE, In the preparation of silicone-coated membranes for use in blood oxygenators, plasma polymerization of octamethylcyclotetrasiloxane in celgard membrane showed better blood compatibility than silastic sheeting or glass., Octamethylcyclotetrasiloxane is used to replace isopropyl myristate, isopropyl palmitate, or other oily carriers used in deodorants or antiperspirants., In a study dated from September 2, 2004 the Danish EPA found octamethylcyclotetrasiloxane in creams and styling supplies at average concentrations of 0.3 and 0.8%. The study states that the materials would no longer be used in these products during the upcoming year., Cyclomethicone is a generic name for several cyclic dimethyl polysiloxane compounds ... it refers not only to octamethylcyclotetrasiloxane (D4), but also to cyclotrisiloxane (D3), cyclope.
Category: Organic Chemicals.
Independent reference data for Octamethyl cyclotetrasiloxane (CAS 556-67-2), compiled from public chemistry databases.
| CAS Registry Number | 556-67-2 |
|---|---|
| PubChem CID | 11169 |
| Molecular formula | C8H24O4Si4 |
| IUPAC name | 2,2,4,4,6,6,8,8-octamethyl-1,3,5,7,2,4,6,8-tetraoxatetrasilocane |
| UNII (FDA) | CZ227117JE |
| Molecular Weight | 296.61 |
|---|---|
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 0 |
| Exact Mass | 296.07516538 |
| Monoisotopic Mass | 296.07516538 |
| Topological Polar Surface Area | 36.9 |
| Heavy Atom Count | 16 |
| Boiling Point | 175 °C |
|---|---|
| Boiling Point | BP: 74 °C at 20 mm Hg |
| Boiling Point | 175 °C @760 [mm Hg] |
| Melting Point | 17.5 °C |
| Flash Point | 55 °C (131 °F) - closed cup |
| Flash Point | 56 °C |
| Solubility | In water, 0.056 mg/L at 23 °C |
| Density | 0.9558 @25 °C |
| Vapor Pressure | 1.05 [mmHg] |
| Vapor Pressure | 1.05 mm Hg at 25 °C |
OCTAMETHYLCYCLOTETRASILOXANE; 556-67-2; Cyclotetrasiloxane, octamethyl-; 2,2,4,4,6,6,8,8-Octamethyl-1,3,5,7,2,4,6,8-tetraoxatetrasilocane; Oktamethylcyklotetrasiloxan; OMCTS; Cyclic dimethylsiloxane tetramer; Cyclomethicone 4; NUC silicone VS 7207; Union carbide 7207; Silicone SF 1173; DTXSID7027205; KF 994; SF 1173; UC 7207; VS 7207
| Regulatory & Food Contact | FDA Cumulative Estimated Daily Intake (CEDI): FCS OCTAMETHYLCYCLOTETRASILOXANE (D4) CIR / INCI: Cosmetics ingredient -> Conditioning/Emollient; Moisturizing/Humectant CIR / INCI: Solvent; Emollient; Viscosity controlling; Antistatic; Humectant; Hair conditioning |
|---|---|
| GHS notification summary | 0.1% (2 / 4700) |
| GHS notification summary | 0.1% (2 / 4700) |
|---|---|
| Reported hazard statements | H410, H226 (72.1%), H361 (96%), H413 (89.7%) |
H361f ***: Suspected of damaging fertility [Warning Reproductive toxicity]
H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
Octamethyl cyclotetrasiloxane · CAS 556-67-2 · C8H24O4Si4. UNII CZ227117JE. Boiling Point: 175 °C; Boiling Point: BP: 74 °C at 20 mm Hg; Boiling Point: 175 °C @760 [mm Hg].
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 八甲基环四硅氧烷