O-Acetylsalicylic acid

O-Acetylsalicylic acid (CAS 98201-60-6) — formula C9H8O4, molecular weight 180.16; category organic chemicals.

Product Overview

Applications

Documented applications: Uses: Used in manufacturing and health care, [ACGIH TLVs and BEIs], Therapeutic Category: Analgesic, antipyretic, anti-inflammatory, antithrombotic., Therapeutic Category (Vet): Analgesic, MEDICATION, CHEMICAL PROFILE: Virtually all aspirin is used in pharmaceutical products in aspirin tablets or in concert with other ingredients (1981), For more Uses (Complete) data for ACETYLSALICYLIC ACID (7 total), please visit the HSDB record page., Use (kg) in Switzerland (2009): >50000, Use (kg, approx.) in Germany (2009): >500000, exact) in Germany (2009): 621516, Use (kg) in USA (2002): 795000, Use (kg) in France (2004): 396212, Consumption (g per capita) in Switzerland (2009): 6.4, Consumption (g per capita, approx.) in Germany (2009): 6.1, exact) in Germany (2009): 7.6, Consumption (g per capita) in the USA (2002): 2.8, Consumption (g per capita) in France (2004): 6.6, Excretion rate: 0.1, Calculated removal (%): 92.1, For use in the temporary relief of various forms of pain, inflammation associated with various conditions (including rheumatoid arthritis, juvenile rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, and ankylosing spondylitis), and is also used to reduce the risk of death and, or nonfatal myocardial infarction in patients with a previous infarction or unstable angina pectoris., Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients, Pharmaceuticals -> Animal Drugs -> Approved in Taiwan, Household Products: Cosmetics product ingredient: Aspirin (Acetylsalicylic acid), Source: Aspirin is a non-steroidal anti-inflammatory over-the-counter drug. Aspirin relieves pain and reduces fever. Aspirin prevents blood from clotting quickly. Aspirin is added to cosmetics in order to reduce irritation and inflammation., Potential health impacts: The major routes of exposure to aspirin in cosmetics are through the skin or by ingestion. Some people are sensitive to aspirin and can have severe reactions to small amounts. In high doses, aspirin can affect the liver. Aspirin is not recommended for children because of a link to Reye Syndrome, a serious liver disease. Aspirin is generally not recommended for use as a pain reliever during pregnancy, because it can cause changes in the heart of the unborn child and may delay or prolong labor. It also increases the risk of bleeding., The U.S. Food and Drug Administration (FDA) classifies aspirin as FDA Pregnancy Category D, there is a known risk to the fetus when the drug is used during pregnancy, but potential benefits may sometimes outweigh the risk. California Proposition 65 lists aspirin as a chemical known to cause developmental effects and reproductive harm., Product count: 11, Methods of Manufacturing: Acetylsalicylic acid is prepared by reacting acetic anhydride with salicylic acid at a temperature of <90 °C either in a solvent (e.g., acetic acid or aromatic, acyclic, or chlorinated hydrocarbons) or by the addition of catalysts such as acids or tertiary amines., Manufacture from salicylic acid and acetic anhydride. ... Crystallization from acetone.., Impurities: 4-hydroxybenzoic acid, 4-hydroxybenzene-1, 3-dicarboxylic acid (4-hydroxyisophthalic acid), salicylic acid, 2-[[2-(acetyloxy)benzoyl]oxy]benzoic acid (acetylsalicylsalicylic acid), 2-[(2-hydroxybenzoyl)oxy]benzoic acid (salicylsalicylic acid), 2-(acetyloxy)benzoic anhydride (acetylsalicylic anhydride), Formulations, Preparations: Aspirin Formulations:, Table: Aspirin Formulations: [Table#1910], Consumption Patterns: 54% AS AN ANALGESIC IN COMBINATION WITH OTHER ACTIVE OR INERT INGREDIENTS, 46% AS AN ANALGESIC IN SINGLE INGREDIENT ASPIRIN TABLETS (1973), CHEMICAL PROFILE: Aspirin. Almost all aspirin manufactured in the US is used in aspirin tablets, pharmaceutical products or in conjunction with other ingredients for its analgesic and antipyretic properties. Approx 10% of US production is exported in bulk., CHEMICAL PROFILE: Aspirin. Demand: 1986: 29.5 million lb, 1987: 30.0 million lb, 1991, projected, : 31.8 million lb., pharmaceutical products or in conjunction with other ingredients for its analgesic and antipyretic properties. Approximately 5% of US production is exported in bulk., For more Consumption Patterns (Complete) data for ACETYLSALICYLIC ACID (8 total), U.S. Production: (1972) 1.59X10+10 GRAMS, (1975) 1.16X10+10 GRAMS, (1984) 1.54X10+10 g, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#1911], For more U.S. Production (Complete) data for ACETYLSALICYLIC ACID (7 total), U.S. Imports: (1972) 2.04X10+8 GRAMS, (1975) 1.42X10+8 GRAMS, (1984) 1.65x10+9 g, CHEMICAL PROFILE: Aspirin imports were 2.6 million lb last year, 1989, ., For more U.S. Imports (Complete) data for ACETYLSALICYLIC ACID (6 total), U.S. Exports: (1972) 8.74X10+8 GRAMS (BULK), (1975) 1.06X10+8 GRAMS, (1984) 1.26X10+9 g (bulk), CHEMICAL PROFILE: Aspirin exports were 1.3 million lb, in 1989, For more U.S. Exports (Complete) data for ACETYLSALICYLIC ACID (7 total), General Manufacturing Information: Benzoic acid, 2-(acetyloxy)-: ACTIVE, Acetylsalicylic acid otherwise known as aspirin, has been the most widely used over the counter drug..

Technical Profile

What this product is

O-Acetylsalicylic acid is a carbon-based organic compound with CAS registry number 98201-60-6 and molecular formula C9H8O4 (molecular weight 180.16), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 98201-60-6

Its molecular formula C9H8O4 comprises 9 C, 8 H, 4 O atoms.

Also known as: O-Acetylsalicylic acid · O-乙酰水杨酸

Category: organic chemicals

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