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纳美芬

CAS 55096-26-9C21H25NO3MW 339.4

本页收录 纳美芬,CAS 登记号为 55096-26-9,分子式 C21H25NO3,分子量 339.4,归类于有机化学品。作为主营产品之一,济南圣和化工有限公司 可提供从公斤级到吨级的稳定供货,随货附 COA 与质检资料。

产品概览

CAS号55096-26-9
分子式C21H25NO3
分子量339.4
熔点105-110 °C
LogP2.7
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域有机化学品
类别有机化学品

应用领域

有机化学品

该产品的下游应用集中在有机化学品。不同客户工艺差异较大,我们支持按需提供样品与小批量试用。

包装与储存

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
运输常规化工运输
样品可协商提供
交期现货/按订单安排

采购提示:本产品按按订单/批次确认(不公开发布)起订发货,收到货物后请先核对包装完好性再行入库。储存条件为阴凉干燥、密封保存;如需 MSDS 或运输说明,可在询价时一并索取。

质量与文件

每批产品随货提供 COA(分析证书);可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

作为化工原料供应服务商,济南圣和化工有限公司 长期服务于化工贸易、食品添加、医药中间体、日化原料等行业的采购需求。除 纳美芬 外,您还可以在站内按 CAS 号或产品分类检索更多品类,获取规格与报价。

常见问题

纳美芬 的 CAS 号是多少?

纳美芬 的 CAS 号为 55096-26-9。

该产品的纯度和包装规格是什么?

常规纯度规格为 按批次COA提供(不公开发布),包装为 按订单/批次确认(不公开发布),随货提供 COA。

纳美芬 有什么用途?

主要应用于有机化学品。

如何购买或获取报价?

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系,注明产品名称、CAS 号与需求数量,一个工作日内回复报价。供应商:济南圣和化工有限公司。

PubChem 公开数据

Description

nalmefene · CAS 55096-26-9 · C21H25NO3. UNII TOV02TDP9I. Melting Point: 105-110 °C; Dissociation Constants: 7.6.

Identification

CAS Registry Number55096-26-9
PubChem CID5284594
Molecular formulaC21H25NO3
IUPAC name(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
UNII (FDA)TOV02TDP9I

Computed Descriptors

Molecular Weight339.4
XLogP32.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass339.18344366
Monoisotopic Mass339.18344366
Topological Polar Surface Area52.9
Heavy Atom Count25
Formal Charge0

Physical & Chemical Properties

Melting Point105-110 °C
Dissociation Constants7.6

Physical description & handling notes

  • Crystals from ethyl acetate
  • Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
  • pKa = 7.63 /Nalmefene hydrochloride/
  • MW: 375.9. White to off-white crystalline powder ... freely soluble in water up to 130 mg/L and slightly soluble in chloroform up to 0.13 mg/mL ... no longer available in the US /Revex/
  • Nalmetrene
  • REVEX

GHS Hazard Classification

Reported hazard statementsH315 (97.5%), H319 (97.5%), H335 (97.5%)

H315 (97.5%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (97.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Documented Uses

  • Is a pure opioid receptor antagonist ... used to reverse opioid intoxication and for the treatment of opioid dependence. The compound is in clinical development for the treatment of alcoholism, to support smoking cessation and to control pathological gambling.
  • Therapeutic Category: Narcotic antagonist
  • Therapeutic Category (Vet): Narcotic antagonist
  • Nalmefene is synthesized by a Wittig reaction of naltrexone with triphenylmethylphosphonium bromide in DMSO under basic catalysis of NaH.
  • Preparation: J. Fishman, US 3814768 (1974 to M.J. Lewenstein)
  • Nalmafene is a relatively pure mu-receptor antagonist that is more potent than naloxone.

Synonyms

nalmefene; Nalmetrene; 55096-26-9; Nalmefeno; ORF-11676; Nalmefenum; ORF 11676; DTXSID8023347; TOV02TDP9I; SRD174; JKB-121; SRD-174; ORF 1167; ORF-1167; (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinon-3,14-diol; DTXCID903347

Frequently Asked Questions

What are the CAS number and molecular formula of nalmefene?

CAS 55096-26-9; molecular formula C21H25NO3; molecular weight — g/mol.

What other names is nalmefene known by?

nalmefene, Nalmetrene, 55096-26-9, Nalmefeno, ORF-11676, Nalmefenum.

Is nalmefene classified as hazardous?

Hazard statements reported: H315, H319, H335.

What are the key physical properties of nalmefene?

Melting Point: 105-110 °C; Dissociation Constants: 7.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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