萘夫西林钠（CAS 985-16-0）：分子式 C21H22N2O5S、分子量 414.5。
| CAS号 | 985-16-0 |
|---|---|
| 分子式 | C21H22N2O5S |
| 分子量 | 414.5 |
| LogP | 3.3 |
| 应用领域 | Uses: MEDICATION、MEDICATION (VET)、Use Classification: Pharmaceuticals、Methods of Manufacturing: 6-AMINOPENICILLANIC ACID IS ACYLATED BY TREATMENT WITH 2-ETHOXY-1-NAPHTHOYL CHLORIDE IN ANHYDROUS ORG SOLVENT CONTAINING TRIETHYLAMINE. AQ EXTRACT OF THIS...IS ADMIXED WITH WATER-IMMISCIBLE SOLVENT & NAFCILLIN PPTD BY ADDN OF SULFURIC ACID. NAFCILLIN SODIUM IS PPTD BY MIXING ETHANOLIC SOLN OF ACID & SODIUM ETHYLHEXANOATE、Formulations、Preparations: POWDER FOR INJECTION IS BUFFERED WITH 40 MG SODIUM CITRATE、G OF DRUG、CAPSULES & TABLETS ARE BUFFERED WITH CALCIUM CARBONATE.、NAFCILLIN SODIUM、USP (UNIPEN)...AVAILABLE FOR ORAL & PARENTERAL USE. CAPSULES USUALLY CONTAIN 250 MG...DRUG. SOLN IS ALSO MARKETED FOR ORAL USE. STERILE PREPN FOR INJECTION...AMPULS CONTAINING 500 MG、1 G、OR 2 G OF SALT.、General Manufacturing Information: ...A SEMISYNTHETIC PENICILLIN、DERIVED FROM 6-AMINOPENICILLANIC ACID、IS HIGHLY RESISTANT TO PENICILLINASE...、PATENTS: US PATENT 3、157、639.、POTENCY: NOT LESS THAN 820 UG OF NAFCILLIN、MG.、Doyle et al. Brit pat 880、400 (1961 to Beecham)、Nafcillin sodium |
登记用途：Uses: MEDICATION、MEDICATION (VET)、Use Classification: Pharmaceuticals、Methods of Manufacturing: 6-AMINOPENICILLANIC ACID IS ACYLATED BY TREATMENT WITH 2-ETHOXY-1-NAPHTHOYL CHLORIDE IN ANHYDROUS ORG SOLVENT CONTAINING TRIETHYLAMINE. AQ EXTRACT OF THIS...IS ADMIXED WITH WATER-IMMISCIBLE SOLVENT & NAFCILLIN PPTD BY ADDN OF SULFURIC ACID. NAFCILLIN SODIUM IS PPTD BY MIXING ETHANOLIC SOLN OF ACID & SODIUM ETHYLHEXANOATE、Formulations、Preparations: POWDER FOR INJECTION IS BUFFERED WITH 40 MG SODIUM CITRATE、G OF DRUG、CAPSULES & TABLETS ARE BUFFERED WITH CALCIUM CARBONATE.、NAFCILLIN SODIUM、USP (UNIPEN)...AVAILABLE FOR ORAL & PARENTERAL USE. CAPSULES USUALLY CONTAIN 250 MG...DRUG. SOLN IS ALSO MARKETED FOR ORAL USE. STERILE PREPN FOR INJECTION...AMPULS CONTAINING 500 MG、1 G、OR 2 G OF SALT.、General Manufacturing Information: ...A SEMISYNTHETIC PENICILLIN、DERIVED FROM 6-AMINOPENICILLANIC ACID、IS HIGHLY RESISTANT TO PENICILLINASE...、PATENTS: US PATENT 3、157、639.、POTENCY: NOT LESS THAN 820 UG OF NAFCILLIN、MG.、Doyle et al. Brit pat 880、400 (1961 to Beecham)、Nafcillin sodium。
萘夫西林钠 是一种化工化合物，登记 CAS 号为 985-16-0，分子式 C21H22N2O5S（分子量 414.5）。
登记 CAS 号：985-16-0
其分子式 C21H22N2O5S 由 21 个碳、22 个氢、2 个氮、5 个氧、1 个硫 组成。
别名/同义词：萘夫西林钠 · Nafcillin sodium
萘夫西林钠 的 CAS 登记号为 985-16-0。
分子式 C21H22N2O5S，分子量 414.5。
别名/同义词：萘夫西林钠、Nafcillin sodium。
登记用途：Uses: MEDICATION、MEDICATION (VET)、Use Classification: Pharmaceuticals、Methods of Manufacturing: 6-AMINOPENICILLANIC ACID IS ACYLATED BY TREATMENT WITH 2-ETHOXY-1-NAPHTHOYL CHLORIDE IN ANHYDROUS ORG SOLVENT CONTAINING TRIETHYLAMINE. AQ EXTRACT OF THIS...IS ADMIXED WITH WATER-IMMISCIBLE SOLVENT & NAFCILLIN PPTD BY ADDN OF SULFURIC ACID. NAFCILLIN SODIUM IS PPTD BY MIXING ETHANOLIC SOLN OF ACID & SODIUM ETHYLHEXANOATE、Formulations、Preparations: POWDER FOR INJECTION IS BUFFERED WITH 40 MG SODIUM CITRATE、G OF DRUG、CAPSULES & TABLETS ARE BUFFERED WITH CALCIUM CARBONATE.、NAFCILLIN SODIUM、USP (UNIPEN)...AVAILABLE FOR ORAL & PARENTERAL USE. CAPSULES USUALLY CONTAIN 250 MG...DRUG. SOLN IS ALSO MARKETED FOR ORAL USE. STERILE PREPN FOR INJECTION...AMPULS CONTAINING 500 MG、1 G、OR 2 G OF SALT.、General Manufacturing Information: ...A SEMISYNTHETIC PENICILLIN、DERIVED FROM 6-AMINOPENICILLANIC ACID、IS HIGHLY RESISTANT TO PENICILLINASE...、PATENTS: US PATENT 3、157、639.、POTENCY: NOT LESS THAN 820 UG OF NAFCILLIN、MG.、Doyle et al. Brit pat 880、400 (1961 to Beecham)、Nafcillin sodium。
萘夫西林钠（CAS 985-16-0）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 985-16-0 |
|---|---|
| PubChem CID | 8982 |
| Molecular formula | C21H22N2O5S |
| IUPAC name | (2S,5R,6R)-6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| UNII (FDA) | 4CNZ27M7RV |
| Molecular Weight | 414.5 |
|---|---|
| XLogP3 | 2.9 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 5 |
| Exact Mass | 414.12494298 |
| Monoisotopic Mass | 414.12494298 |
| Topological Polar Surface Area | 121 |
| Heavy Atom Count | 29 |
| Solubility | 1.72e-02 g/L |
|---|---|
| LogP | 3.3 |
nafcillin; 147-52-4; Naphcillin; Nafcilina; Nafcilline; Nafcillinum; Nafcilin-1; (2-Ethoxy-1-naphthyl)penicillin; (2-ethoxy-1-naphthalenyl)penicillin; CHEBI:7447; Penicillin, (2-ethoxy-1-naphthalenyl)-; 4CNZ27M7RV; Penicillin, (2-ethoxy-1-naphthyl)-; 6-(2-ethoxy-1-naphthamido)penicillanic acid; DTXSID8023343; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-ethoxy-1-naphthamido)-3,3-dimethyl-7-oxo-
| Reported hazard statements | H317 (100%), H334 (100%) |
|---|
H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]
H334 (100%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]
Nafcillin sodium · CAS 985-16-0 · C21H22N2O5S. UNII 4CNZ27M7RV. Solubility: 1.72e-02 g/L; LogP: 3.3.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Nafcillin sodium