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N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine)

CAS 3033-62-3C8H20N2OMW 160.26

N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) (CAS 3033-62-3) — formula C8H20N2O, molecular weight 160.26; category organic chemicals.

Product Overview

CAS Number3033-62-3
Molecular FormulaC8H20N2O
Molecular Weight160.26
Boiling Point372 °F at 760 mmHg (NIOSH, 2024)
LogP0.2
ApplicationsUses: A component (5%) of NIAX Catalyst ESN, along with dimethylaminopropionitrile (95%), used in the past as a catalyst in the manufacture of flexible polyurethane foams, [NIOSH], See Appendix C in NIOSH Pocket Guide. The neurotoxicity was apparently due to DMAPN (dimethylaminopropionitrile). See NIOSHTIC Record # 57566. CIB 26 published by NIOSH & OSHA in 1978., DMAEE is used primarily as a catalyst in the manufacturing of polyurethane foams., Lewis base, Industry Uses: Plasticizer, Catalyst, Intermediate, Propellants, non-motive (blowing agents), Chemical reaction regulator, Consumer Uses: Catalyst, Not Known or Reasonably Ascertainable, Household Products: Information on 2 consumer products that contain Bis(2-(dimethylamino)ethyl) ether in the following categories is provided:, • Home Maintenance, • Inside the Home, Formulations, Preparations: NIAX Catalyst ESN, its components, dimethylaminopropionitrile and bis(2-(dimethylamino)ethyl)ether, U.S. Production: 2023: 4, 000, 000 - <5, 500, 000 lb, 2022: 4, 2021: 5, 000 - <7, 2020: 5, Ethanamine, 2, 2'-oxybis[N, N-dimethyl- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438).[EPA, Office of Pollution Prevention and Toxics, High Production Volume (HPV) Challenge Program. Ethanamine, 2'-oxybis, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7734], [US EPA, Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Ethanamine, Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Ethanamine, N-dimethyl-. Aggregated National Production Volume: 1 to < 10 million lbs.[US EPA, Non-Confidential 2006 Inventory Update Reporting. National Chemical Information. Ethanamine, General Manufacturing Information: All Other Basic Organic Chemical Manufacturing, Textiles, apparel, and leather manufacturing, Construction, Furniture and Related Product Manufacturing, Plastics Product Manufacturing, Electrical Equipment, Appliance, and Component Manufacturing, Transportation Equipment Manufacturing, N-dimethyl-: ACTIVE
CategoryOrganic Chemicals

Applications

Documented applications: Uses: A component (5%) of NIAX Catalyst ESN, along with dimethylaminopropionitrile (95%), used in the past as a catalyst in the manufacture of flexible polyurethane foams, [NIOSH], See Appendix C in NIOSH Pocket Guide. The neurotoxicity was apparently due to DMAPN (dimethylaminopropionitrile). See NIOSHTIC Record # 57566. CIB 26 published by NIOSH & OSHA in 1978., DMAEE is used primarily as a catalyst in the manufacturing of polyurethane foams., Lewis base, Industry Uses: Plasticizer, Catalyst, Intermediate, Propellants, non-motive (blowing agents), Chemical reaction regulator, Consumer Uses: Catalyst, Not Known or Reasonably Ascertainable, Household Products: Information on 2 consumer products that contain Bis(2-(dimethylamino)ethyl) ether in the following categories is provided:, • Home Maintenance, • Inside the Home, Formulations, Preparations: NIAX Catalyst ESN, its components, dimethylaminopropionitrile and bis(2-(dimethylamino)ethyl)ether, U.S. Production: 2023: 4, 000, 000 - <5, 500, 000 lb, 2022: 4, 2021: 5, 000 - <7, 2020: 5, Ethanamine, 2, 2'-oxybis[N, N-dimethyl- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438).[EPA, Office of Pollution Prevention and Toxics, High Production Volume (HPV) Challenge Program. Ethanamine, 2'-oxybis, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7734], [US EPA, Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Ethanamine, Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Ethanamine, N-dimethyl-. Aggregated National Production Volume: 1 to < 10 million lbs.[US EPA, Non-Confidential 2006 Inventory Update Reporting. National Chemical Information. Ethanamine, General Manufacturing Information: All Other Basic Organic Chemical Manufacturing, Textiles, apparel, and leather manufacturing, Construction, Furniture and Related Product Manufacturing, Plastics Product Manufacturing, Electrical Equipment, Appliance, and Component Manufacturing, Transportation Equipment Manufacturing, N-dimethyl-: ACTIVE.

Technical Profile

What this product is

N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) is a carbon-based organic compound with CAS registry number 3033-62-3 and molecular formula C8H20N2O (molecular weight 160.26), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 3033-62-3

Its molecular formula C8H20N2O comprises 8 C, 20 H, 2 N, 1 O atoms.

Also known as: N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) · bis(dimethylaminoethyl) ether

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine)?

The CAS registry number of N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) is 3033-62-3.

What is the molecular formula and molecular weight of N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine)?

Molecular formula C8H20N2O, molecular weight 160.26.

What other names is N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) known by?

It is also registered under: N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine), bis(dimethylaminoethyl) ether.

What are the documented applications of N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine)?

Recorded applications: Uses: A component (5%) of NIAX Catalyst ESN, along with dimethylaminopropionitrile (95%), used in the past as a catalyst in the manufacture of flexible polyurethane foams, [NIOSH], See Appendix C in NIOSH Pocket Guide. The neurotoxicity was apparently due to DMAPN (dimethylaminopropionitrile). See NIOSHTIC Record # 57566. CIB 26 published by NIOSH & OSHA in 1978., DMAEE is used primarily as a catalyst in the manufacturing of polyurethane foams., Lewis base, Industry Uses: Plasticizer, Catalyst, Intermediate, Propellants, non-motive (blowing agents), Chemical reaction regulator, Consumer Uses: Catalyst, Not Known or Reasonably Ascertainable, Household Products: Information on 2 consumer products that contain Bis(2-(dimethylamino)ethyl) ether in the following categories is provided:, • Home Maintenance, • Inside the Home, Formulations, Preparations: NIAX Catalyst ESN, its components, dimethylaminopropionitrile and bis(2-(dimethylamino)ethyl)ether, U.S. Production: 2023: 4, 000, 000 - <5, 500, 000 lb, 2022: 4, 2021: 5, 000 - <7, 2020: 5, Ethanamine, 2, 2'-oxybis[N, N-dimethyl- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438).[EPA, Office of Pollution Prevention and Toxics, High Production Volume (HPV) Challenge Program. Ethanamine, 2'-oxybis, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7734], [US EPA, Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Ethanamine, Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Ethanamine, N-dimethyl-. Aggregated National Production Volume: 1 to < 10 million lbs.[US EPA, Non-Confidential 2006 Inventory Update Reporting. National Chemical Information. Ethanamine, General Manufacturing Information: All Other Basic Organic Chemical Manufacturing, Textiles, apparel, and leather manufacturing, Construction, Furniture and Related Product Manufacturing, Plastics Product Manufacturing, Electrical Equipment, Appliance, and Component Manufacturing, Transportation Equipment Manufacturing, N-dimethyl-: ACTIVE.

Which category does N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) belong to?

Category: Organic Chemicals.

PubChem Public Data

Independent reference data for N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) (CAS 3033-62-3), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number3033-62-3
PubChem CID18204
Molecular formulaC8H20N2O
IUPAC name2-[2-(dimethylamino)ethoxy]-N,N-dimethylethanamine
UNII (FDA)NL66Q36V7L

Computed descriptors

Molecular Weight160.26
XLogP30.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count6
Exact Mass160.157563266
Monoisotopic Mass160.157563266
Topological Polar Surface Area15.7
Heavy Atom Count11

Physicochemical values on record

Boiling Point372 °F at 760 mmHg (NIOSH, 2024)
Boiling Point80 °C at 15 mm Hg
Boiling Point372 °F
Flash Point79.4 °C (Open cup)

Documented uses on record

    A component (5%) of NIAX Catalyst ESN, along with dimethylaminopropionitrile (95%); used in the past as a catalyst in the manufacture of flexible polyurethane foams; [NIOSH]See Appendix C in NIOSH Pocket Guide. The neurotoxicity was apparently due to DMAPN (dimethylaminopropionitrile). See NIOSHTIC Record # 57566. CIB 26 published by NIOSH & OSHA in 1978.

    Synonyms and trade names

    3033-62-3; BIS(2-DIMETHYLAMINOETHYL) ETHER; Bis(2-dimethylaminoethyl)ether; Kalpur PC; Niax A 1; Toyocat ET; Toyocat ETS; Dabco BL 11; Texacat ZF 20; Dabco BL 19I; Dabco BL 19; Niax A 4; Niax A 99; A 99 (Amine); Bis(2-(dimethylamino)ethyl)ether; Bis(2-(dimethylamino)ethyl) ether

    GHS hazard classification

    Reported hazard statementsH302 (95.7%), H311 (99.4%), H314 (99.4%), H318 (78.1%), H332 (86.2%), H412 (25.1%), H227, H330

    H302 (95.7%): Harmful if swallowed [Warning Acute toxicity, oral]

    H311 (99.4%): Toxic in contact with skin [Danger Acute toxicity, dermal]

    What the public record says

    N,N,N',N'-tetramethyl-2,2'-oxybis(ethylamine) · CAS 3033-62-3 · C8H20N2O. UNII NL66Q36V7L. Boiling Point: 372 °F at 760 mmHg (NIOSH, 2024); Boiling Point: 80 °C at 15 mm Hg; Boiling Point: 372 °F.

    Physical description and handling notes

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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