N-氨甲酰-L-谷氨酸

Name: N-氨甲酰-L-谷氨酸
Brand: 济南圣和化工有限公司

CAS 1188-38-1C6H10N2O5MW 190.15

济南圣和化工有限公司现供应有机化学品——N-氨甲酰-L-谷氨酸（CAS 1188-38-1），分子式 C6H10N2O5，分子量 190.15。本页理化参数仅供参考，实际常规纯度按批次COA提供(不公开发布)，以批次 COA 及订单确认为准，支持批量采购与长期供货协议。

产品概览

CAS号	1188-38-1
分子式	C6H10N2O5
分子量	190.15
LogP	-1.097
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	有机化学品
类别	有机化学品

应用领域

有机化学品

该产品的下游应用集中在有机化学品。不同客户工艺差异较大，我们支持按需提供样品与小批量试用。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供应说明：N-氨甲酰-L-谷氨酸常规包装为按订单/批次确认(不公开发布)，储存时应密封置于阴凉干燥处，避免与氧化剂混放。济南圣和化工有限公司支持国内物流发货，大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

济南圣和化工有限公司位于山东济南，主营化工原料供应，精选产品 3,000+ 种，覆盖有机化学品、无机化学品、食品添加剂、医药中间体等 12 大分类。我们随货提供 COA 分析证书，一个工作日内回复报价，欢迎国内外采购方长期合作。

常见问题

N-氨甲酰-L-谷氨酸的 CAS 号是多少？

N-氨甲酰-L-谷氨酸的 CAS 号为 1188-38-1。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

N-氨甲酰-L-谷氨酸有什么用途？

主要应用于有机化学品。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

N-carbamyl-L-glutamic acid · CAS 1188-38-1 · C6H10N2O5. UNII 5L0HB4V1EW. LogP: -1.097.

Identification

CAS Registry Number	1188-38-1
PubChem CID	121396
Molecular formula	C6H10N2O5
IUPAC name	(2S)-2-(carbamoylamino)pentanedioic acid
UNII (FDA)	5L0HB4V1EW

Computed Descriptors

Molecular Weight	190.15
XLogP3	-2.4
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	190.05897142
Monoisotopic Mass	190.05897142
Topological Polar Surface Area	130
Heavy Atom Count	13
Formal Charge	0

Physical & Chemical Properties

LogP	-1.097

Physical description & handling notes

Solid
The median Tmax of Carbaglu was 3 hours (range: 2-4). The daily dose of carglumic acid ranges from 100 to 250 mg/kg and this does are normally adjusted to maintain normal plasma levels of ammonia.

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (100%), H319 (100%), H335 (100%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

For the treatment of acute and chronic hyperammonaemia in patients with N-acetylglutamate synthase (NAGS) deficiency. This enzyme is an important component of the urea cycle to prevent build up of neurotoxic ammonium in the blood.
Carglumic acid is an orphan drug and a derivative of N-acetylglutamate that activates the first enzyme in the urea cycle that is responsible for removal and detoxification of ammonia, making this drug a valuable agent for therapy of hyperammonemia caused by rare forms of urea cycle defects. Clinical experience with carglumic acid is limited, but it has not been linked to significant serum enzyme elevations during therapy or to instances of clinically apparent acute liver injury.
Take before a meal. Take carglumic acid right before eating.
Take with plain water. Carglumic acid tablets are dispersed in water to produce an oral suspension and should not be swallowed whole.
Established Pharmacologic Class [EPC] - Carbamoyl Phosphate Synthetase 1 Activator
Mechanisms of Action [MoA] - Carbamoyl Phosphate Synthetase 1 Activators

Synonyms

Carglumic acid; 1188-38-1; N-Carbamyl-L-glutamic acid; Carbaglu; N-Carbamoyl-L-glutamic acid; (2S)-2-(carbamoylamino)pentanedioic acid; Ureidoglutaric acid; Carbamylglutamic acid; Carbamino-L-glutamic acid; L-N-Carbamoylglutamic acid; acido carglumico; acide carglumique; L-Glutamic acid, N-(aminocarbonyl)-; DTXSID7046706; acidum carglumicum; 5L0HB4V1EW

Frequently Asked Questions

What are the CAS number and molecular formula of N-carbamyl-L-glutamic acid?

CAS 1188-38-1; molecular formula C6H10N2O5; molecular weight — g/mol.

What other names is N-carbamyl-L-glutamic acid known by?

Carglumic acid, 1188-38-1, N-Carbamyl-L-glutamic acid, Carbaglu, N-Carbamoyl-L-glutamic acid, (2S)-2-(carbamoylamino)pentanedioic acid.

Is N-carbamyl-L-glutamic acid classified as hazardous?

Hazard statements reported: H302, H315, H319, H335.

What are the key physical properties of N-carbamyl-L-glutamic acid?

LogP: -1.097.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.