n-Butyl-p-Aminobenzoate (CAS 94-25-7) — formula C11H15NO2, molecular weight 193.24; category organic chemicals.
| CAS Number | 94-25-7 |
|---|---|
| Molecular Formula | C11H15NO2 |
| Molecular Weight | 193.24 |
| Melting Point | 136 °F (NTP, 1992) |
| Boiling Point | 343 to 345 °F at 8 mmHg (NTP, 1992) |
| LogP | 2.87 |
| Applications | Uses: Used as a local anesthetic and in burn treatment ointments and suntan preparations, [Hawley] Used essentially 100% as a local anesthetic, [HSDB], MEDICATION, MEDICATION (VET), Methods of Manufacturing: ESTERIFICATION OF P-NITROBENZOIC ACID WITH N-BUTYL ALCOHOL FOLLOWED BY REDUCTION WITH IRON FILINGS AND HYDROCHLORIC ACID, PREPARED BY ESTERIFYING P-NITROBENZOIC ACID WITH N-BUTYL ALCOHOL & REDUCING NITRO GROUP TO AMINO GROUP WITH IRON FILINGS & HCL., Prepn: Brill, J. Am. Chem. Soic. 43, 1322 (1921), Adams, Volwiler, U.S. pat 1, 440, 652 (1923 to Abbott), Brit. pat. 252, 870, C.A. 17, 1243 (1923), C.A. 21, 2478 (1927)., Produced by the esterification of 4-nitrobenzoyl chloride with n-butanol and reduction of the resulting nitroester., Formulations, Preparations: ... MAY BE APPLIED AS DUSTING POWDERS, UNDIL OR DIL WITH STERILE TALC. THEY ARE SOL IN OIL & MAY BE INC IN OILY SOLN, OINTMENTS, & SUPPOSITORIES., ANESTHETICS OF LOW SOLUBILITY, Grade: NF, Consumption Patterns: ESSENTIALLY 100% AS AN ANESTHETIC, U.S. Production: (1978) GREATER THAN 1.36X10+6 G (INCL PICRATE), (1979) GREATER THAN 1.36X10+6 G (INCL PICRATE), U.S. Imports: (1977) No Data, (1979) No Data, U.S. Exports: (1977) No Data, General Manufacturing Information: Benzoic acid, 4-amino-, butyl ester: ACTIVE, Available in the United States as a surface anesthetic in the form of a picrate. |
| Category | Organic Chemicals |
Documented applications: Uses: Used as a local anesthetic and in burn treatment ointments and suntan preparations, [Hawley] Used essentially 100% as a local anesthetic, [HSDB], MEDICATION, MEDICATION (VET), Methods of Manufacturing: ESTERIFICATION OF P-NITROBENZOIC ACID WITH N-BUTYL ALCOHOL FOLLOWED BY REDUCTION WITH IRON FILINGS AND HYDROCHLORIC ACID, PREPARED BY ESTERIFYING P-NITROBENZOIC ACID WITH N-BUTYL ALCOHOL & REDUCING NITRO GROUP TO AMINO GROUP WITH IRON FILINGS & HCL., Prepn: Brill, J. Am. Chem. Soic. 43, 1322 (1921), Adams, Volwiler, U.S. pat 1, 440, 652 (1923 to Abbott), Brit. pat. 252, 870, C.A. 17, 1243 (1923), C.A. 21, 2478 (1927)., Produced by the esterification of 4-nitrobenzoyl chloride with n-butanol and reduction of the resulting nitroester., Formulations, Preparations: ... MAY BE APPLIED AS DUSTING POWDERS, UNDIL OR DIL WITH STERILE TALC. THEY ARE SOL IN OIL & MAY BE INC IN OILY SOLN, OINTMENTS, & SUPPOSITORIES., ANESTHETICS OF LOW SOLUBILITY, Grade: NF, Consumption Patterns: ESSENTIALLY 100% AS AN ANESTHETIC, U.S. Production: (1978) GREATER THAN 1.36X10+6 G (INCL PICRATE), (1979) GREATER THAN 1.36X10+6 G (INCL PICRATE), U.S. Imports: (1977) No Data, (1979) No Data, U.S. Exports: (1977) No Data, General Manufacturing Information: Benzoic acid, 4-amino-, butyl ester: ACTIVE, Available in the United States as a surface anesthetic in the form of a picrate..
n-Butyl-p-Aminobenzoate is a carbon-based organic compound with CAS registry number 94-25-7 and molecular formula C11H15NO2 (molecular weight 193.24), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 94-25-7
Its molecular formula C11H15NO2 comprises 11 C, 15 H, 1 N, 2 O atoms.
Also known as: n-Butyl-p-Aminobenzoate · 对氨基苯甲酸正丁酯
Category: organic chemicals
The CAS registry number of n-Butyl-p-Aminobenzoate is 94-25-7.
Molecular formula C11H15NO2, molecular weight 193.24.
It is also registered under: n-Butyl-p-Aminobenzoate, 对氨基苯甲酸正丁酯.
Recorded applications: Uses: Used as a local anesthetic and in burn treatment ointments and suntan preparations, [Hawley] Used essentially 100% as a local anesthetic, [HSDB], MEDICATION, MEDICATION (VET), Methods of Manufacturing: ESTERIFICATION OF P-NITROBENZOIC ACID WITH N-BUTYL ALCOHOL FOLLOWED BY REDUCTION WITH IRON FILINGS AND HYDROCHLORIC ACID, PREPARED BY ESTERIFYING P-NITROBENZOIC ACID WITH N-BUTYL ALCOHOL & REDUCING NITRO GROUP TO AMINO GROUP WITH IRON FILINGS & HCL., Prepn: Brill, J. Am. Chem. Soic. 43, 1322 (1921), Adams, Volwiler, U.S. pat 1, 440, 652 (1923 to Abbott), Brit. pat. 252, 870, C.A. 17, 1243 (1923), C.A. 21, 2478 (1927)., Produced by the esterification of 4-nitrobenzoyl chloride with n-butanol and reduction of the resulting nitroester., Formulations, Preparations: ... MAY BE APPLIED AS DUSTING POWDERS, UNDIL OR DIL WITH STERILE TALC. THEY ARE SOL IN OIL & MAY BE INC IN OILY SOLN, OINTMENTS, & SUPPOSITORIES., ANESTHETICS OF LOW SOLUBILITY, Grade: NF, Consumption Patterns: ESSENTIALLY 100% AS AN ANESTHETIC, U.S. Production: (1978) GREATER THAN 1.36X10+6 G (INCL PICRATE), (1979) GREATER THAN 1.36X10+6 G (INCL PICRATE), U.S. Imports: (1977) No Data, (1979) No Data, U.S. Exports: (1977) No Data, General Manufacturing Information: Benzoic acid, 4-amino-, butyl ester: ACTIVE, Available in the United States as a surface anesthetic in the form of a picrate..
Category: Organic Chemicals.
Independent reference data for n-Butyl-p-Aminobenzoate (CAS 94-25-7), compiled from public chemistry databases.
| CAS Registry Number | 94-25-7 |
|---|---|
| PubChem CID | 2482 |
| Molecular formula | C11H15NO2 |
| IUPAC name | butyl 4-aminobenzoate |
| UNII (FDA) | EFW857872Q |
| Molecular Weight | 193.24 |
|---|---|
| XLogP3 | 2.9 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 5 |
| Exact Mass | 193.110278721 |
| Monoisotopic Mass | 193.110278721 |
| Topological Polar Surface Area | 52.3 |
| Heavy Atom Count | 14 |
| Boiling Point | 343 to 345 °F at 8 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | 173.5 |
| Boiling Point | 173-174 °C @ 8 mm Hg |
| Melting Point | 136 °F (NTP, 1992) |
| Melting Point | 58 |
| Melting Point | 58 °C |
| Solubility | 140 |
| Solubility | In water, 3.35X10+2 mg/l @ 25 °C |
| Vapor Pressure | 0.000299 [mmHg] |
| LogP | 2.87 |
Butyl 4-aminobenzoate; butamben; 94-25-7; Butesine; Butoform; Butyl aminobenzoate; Butylcaine; Planoform; Scuroform; Scuroforme; 4-(Butoxycarbonyl)aniline; Butyl keloform; Benzoic acid, 4-amino-, butyl ester; N-Butyl p-aminobenzoate; p-Aminobenzoic acid butyl ester; 4-Aminobenzoic acid butyl ester
| Reported hazard statements | H315 (100%), H317 (95.3%), H319 (100%), H335 (95.3%) |
|---|
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H317 (95.3%): May cause an allergic skin reaction [Warning Sensitization, Skin]
n-Butyl-p-Aminobenzoate · CAS 94-25-7 · C11H15NO2. UNII EFW857872Q. Boiling Point: 343 to 345 °F at 8 mmHg (NTP, 1992); Boiling Point: 173.5; Boiling Point: 173-174 °C @ 8 mm Hg.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 对氨基苯甲酸正丁酯